How to manage elderly patients with chronic renal failure: Conservative management versus dialysis

Blood Purification

Volumn 26, Issue 1, 2008, Pages 36-40

  Brunori, Giuliano ^a   Viola, Battista Fabio ^a   Maiorca, Paolo ^a   Cancarini, Giovanni ^a  

^a SPEDALI CIVILI   (Italy)

Author keywords

Chronic kidney disease; Dialysis; Elderly; Low protein diet; Uremia

Indexed keywords

AGED; CHRONIC KIDNEY FAILURE; COMORBIDITY; CONFERENCE PAPER; CONSERVATIVE TREATMENT; DIALYSIS; FINANCIAL MANAGEMENT; HOSPITALIZATION; HUMAN; ISCHEMIC HEART DISEASE; LIFE EXPECTANCY; LIFESTYLE MODIFICATION; MEDICAL DECISION MAKING; MORBIDITY; MORTALITY; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN RESTRICTION; QUALITY OF LIFE;

AGED; DIET, PROTEIN-RESTRICTED; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY FAILURE, CHRONIC; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RENAL DIALYSIS; UREMIA;

EID: 38049040858     PISSN: 02535068     EISSN: None     Source Type: Journal    
DOI: 10.1159/000110561     Document Type: Conference Paper

References (24)

1. Krishnan M, Lok CE, Jassal SV: Epidemiology and demographic aspects of treated endstage renal disease in the elderly. Semin Dial 2002;15(suppl 2):79-83.
2. Kurella M, Covinsky KE, Collins AJ, Chertow GM: Octogenarians and nonagenarians starting dialysis in the United States. Ann Intern Med 2007;146:177-183.
3. Lamping DL, Constantinovici N, Roderick P, Normand C, Henderson L, Harris S, Brown E, Gruen R, Victor C: Clinical outcomes, quality of life, and costs in the North Thames Dialysis Study of elderly people on dialysis: a prospective cohort study. Lancet 2000;356:1543-1550.
4. Rayner HC, Pisoni RL, Bommer J, Canaud B, Hecking E, Locatelli F, Piera L, Bragg-Gresham JL, Feldman HI, Goodkin DA, Gillespie B, Wolfe RA, Held PJ, Port FK: Mortality and hospitalization in hemodialysis patients in five European countries: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol Dial Transplant 2004;19:108-120.
5. Chandna SM, Schulz J, Lawrence C, Greenwood R, Farrington K: Is there a rationale for rationing chronic dialysis? A hospital-based cohort study of factors affecting survival and morbidity. BMJ 1999;318:217-223.
6. Kee F, Patterson CC, Wilson EA, McConnell JM, Wheeler SM, Watson JD: Stewardship or clinical freedom? Variations in dialysis decision-making. Nephrol Dial Transplant 2000;15(suppl 10):1647-1657.
7. Joly D, Anglicheau D, Alberti C, Nguyen AT, Touam M, Grünfeld JP, Jungers P: Octogenarians reaching end-stage renal disease: cohort study of decision-making and clinical outcomes. J Am Soc Nephrol 2003;14:1012-1021.
8. Smith C, Silva-Gane M, Chandna S, Warwicher P, Greenwood R, Farrington K: Choosing to not dialyse: evaluation of planned non-dialytic management in a cohort of patients with end-stage renal failure. Nephron Clin Pract 2003;95:c40-c46.
9. Ronsberg F, Isles C, Simpson K, Prescott G: Renal replacement therapy in the over-80s. Age Aging 2005;34(suppl 2)148-152.
10. Schaefer K, Rohrich B: The dilemma of renal replacement therapy in patients over 80 years of age. Dialysis should not be withheld. Nephrol Dial Transplant 1999;14(suppl 1):148-152.
11. Munshi SK, Vijayakumur N, Taub NA, Bhullar H, Lo TC, Warwick G: Outcome of renal replacement therapy in the very elderly. Nephrol Dial Transplant 2001;16(suppl 1):128-133.
12. Chauveau P, Combe C, Laville M, Fouque D, Azar R, Cano N, Canaud B, Roth H, Leverve X, Aparicio M: French Study Group for Nutrition in Dialysis. Factors influencing survival in hemodialysis patients aged older than 75 years: 2.5-year outcome study. Am J Kidney Dis 2001;37(suppl 5):997-1003.
13. Wright LF: Survival in patients with endstage renal disease. Am J Kidney Dis 1991;17(suppl 1):25-28.
14. Fukuhara S, Lopes AA, Bragg-Gresham JL, Kurokawa K, Mapes DL, Akizawa T, Bommer J, Canaud BJ, Port FK, Held PJ: Worldwide Dialysis Outcomes and Practice Patterns Study. Health-related quality of life among dialysis patients on three continents: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Kidney Int 2003;64(suppl 5):1903-1910.
15. Loos C, Briancon S, Frimat L, Hanesse B, Kessler M: Effect of end-stage renal disease on the quality of life of older patients. J Am Geriatr Soc 2003;51(suppl 2):229-233.
16. Weisbord SD, Carmody SS, Bruns FJ, Rotondi AJ, Cohen LM, Zeidel ML, Arnold RM: Symptom burden, quality of life, advance care planning and the potential value of palliative care in severely ill hemodialysis patients. Nephrol Dial Transplant 2003;18 (suppl 7):1345-1352.
17. Murtagh FEM, Marsh JE, Donohoe P, Ekbal NJ, Sheerin NS, Harris FE: Dialysis or not? A comparative survival study of patients over 75 years with chronic kidney disease stage 5. Nephrol Dial Transplant 2007;22:1955-1962.
18. Brunori G, Viola BF, Parrinello G, De Biase V, Como G, Franco V, Garibotto G, Zubani R, Cancarini GC: Efficacy and safety of a very low protein diet when postponing dialysis in the elderly: a prospective randomized multicenter controlled study. Am J Kidney Dis 2007;49:569-580.
19. National Kidney Foundation: KDOQI Clinical Practice Guidelines. I. Initiation of dialysis. Am J Kidney Dis 1997;30:S70-S73.
20. European Best Practice Guidelines Expert Group on Hemodialysis, European Renal Association: Section I. Measurement of renal function, when to refer and when to start dialysis. Nephrol Dial Transplant 2002;17 (suppl 7):7-15.
21. Davies SJ, Phillips L, Naish PF, Russell GI: Quantifying comorbidity in peritoneal dialysis patients and its relationship to other predictors of survival. Nephrol Dial Transplant 2002;17(suppl 6):1085-1092.
22. Klahr S, Levey AS, Beck GJ, Caggiula AW, Hunsicker L, Kusek JW, Striker G: The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of Diet in Renal Disease Study Group. N Engl J Med 1994;330:877-884.
23. Kopple JD, Levey AS, Greene T, Chumlea WC, Gassman JJ, Hollinger DL, Maroni BJ, Merrill D, Scherch LK, Schulman G, Wang SR, Zimmer GS: Effect of dietary protein restriction on nutritional status in the Modification of Diet in Renal Disease Study. Kidney Int 1997;52:778-791.
24. Di Iorio BR, Minutolo R, De Nicola L, Bellizzi V, Catapano F, Iodice C, Rubino R, Conte G: Supplemented very low protein diet ameliorates responsiveness to erythropoietin in chronic renal failure. Kidney Int 2003;64:1822-1828.