Attenuation of muscle metaboreflex in chronic obstructive pulmonary disease

Medicine and Science in Sports and Exercise

Volumn 40, Issue 1, 2008, Pages 9-14

  Roseguini, Bruno T ^a   Alves, Cristiano N ^a   Chiappa, Gaspar R ^a   Stein, Ricardo ^a   Knorst, Marli M ^a,b   Ribeiro, Jorge P ^a,b,c  

^a Hospital of Clinics of Porto Alegre   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Blood flow; Hemodynamic control; Metaboreceptors; Static exercise

Indexed keywords

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD FLOW; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; EXERCISE; FEMALE; HAND GRIP; HEART RATE; HUMAN; HYPOTHESIS; LEG BLOOD FLOW; LUNG HEMODYNAMICS; MALE; MEAN ARTERIAL PRESSURE; MUSCLE CONTRACTION; MUSCLE EXCITATION; MUSCLE EXERCISE; MUSCLE FUNCTION; MUSCLE METABOLISM; MUSCLE REFLEX; MUSCLE SPINDLE AFFERENT NERVE; PATHOLOGICAL REFLEX; REFLEX; SKELETAL MUSCLE; STATIC EXERCISE; VASCULAR RESISTANCE;

BLOOD PRESSURE; CASE-CONTROL STUDIES; EXERCISE TEST; FEMALE; HEART RATE; HEMODYNAMICS; HUMANS; LEG; MALE; METABOLIC DISEASES; MIDDLE AGED; PERFUSION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY FUNCTION TESTS; SICKNESS IMPACT PROFILE;

EID: 38049009430     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/mss.0b013e3181590bd9     Document Type: Article

References (34)

1. Allaire J, Maltais F, Doyon JF, et al. Peripheral muscle endurance and the oxidative profile of the quadriceps in patients with COPD. Thorax. 2004;59:673-8.
2. American Thoracic Society. Standardization of spirometry (update). Am Rev Resp Dis. 1997;136:1285-98.
3. American Thoracic Society/European Respiratory Society. Skeletal muscle dysfunction in chronic obstructive pulmonary disease. Am J Resp Crit Care Med. 1999;159(Suppl):S1-40.
4. Andreas S, Anker SD, Scalon PD, Somers VK. Neurohumoral activation as a link to systemic manifestations of chronic lung disease. Chest. 2005;128:3618-24.
5. Casanova C, Hernandez MC, Sanchez A, et al. Twenty-four hour ambulatory oximetry monitoring in COPD patients with moderate hypoxemia. Respir Care. 2006;51:1416-23.
6. Claassen DE, Morgan DA, Hirai T, Kenney MJ. Nonuniform sympathetic nerve responses after sustained elevation in arterial pressure. Am J Physiol. 1996;271:R1264-9.
7. Coney AM, Bishay M, Marshall JM. Influence of endogenous nitric oxide on sympathetic vasoconstriction in normoxia, acute and chronic systemic hypoxia in the rat. J Physiol. 2004;555:793-804.
8. Crisafulli A, Salis E, Tocco F, et al. Impaired central hemodynamic control and exaggerated vasoconstriction during muscle metaboreflex activation in heart failure patients. Am J Physiol Heart Circ Physiol. 2007;292:H2988-96.
9. Dempsey JA, Sheel AW, Haverkamp HC, Babcock MA, Harms CA. Pulmonary system limitations in health. Can J Appl Physiol. 2003;28(Suppl.):S2-24.
10. Doyle MP, Walker BR. Attenuation of systemic vasoreactivity in chronically hypoxic rats. Am J Physiol. 1991;260:R1114-22.
11. 2- adrenoceptors and neuropeptide Y1 receptors in rats with heart failure. Acta Physiol Scand. 1999;166:285-91.
12. Hansen J, Thomas GD, Jacobsen TN, Victor RG. Muscle metaboreflex triggers parallel sympathetic activation in exercising and resting human skeletal muscle. Am J Physiol. 1994;266:H2508-14.
13. Heindl S, Lehnert M, Criée CP, Hasenfuss G, Andreas S. Marked sympathetic activation in patients with chronic respiratory failure. Am J Resp Crit Care Med. 2001;164:597-601.
14. Heistad DD, Abboud FM, Mark AL, Schmid PG. Impaired reflex vasoconstriction in chronically hypoxemic patients. J Clin Invest. 1972;51:331-7.
15. Hirai T, Musch T, Morgan D, et al. Differential sympathetic nerve responses to nitric oxide synthase inhibition in anesthetized rats. Am J Physiol. 1995;269:R807-13.
16. Jakobsson PL, Jordfeldt L, Brunden A. Skeketal muscle metabolities and fiber types in patients with advanced chronic obstructive pulmonary disease (COPD), with and without chronic respiratory failure. Eur Respir J. 1990;3:192-6.
17. Knudson RJ, Slatin RC, Lebowitz MD, Burrows B. The maximal expiratory flow-volume curve. Normal standards, variability, and effects of age. Am Rev Respir Dis. 1976;113:587-600.
18. Kon H, Nakamura M, Arakawa N, Hiramori K. Muscle metaboreflex is blunted with reduced vascular resistance response of nonexercised limb in patients with chronic heart failure. J Card Fail. 2004;10:503-10.
19. 31P-NMR study of skeletal muscle metabolism in patients with chronic respiratory impairment. Am Rev Resp Dis. 1992;146:1019-24.
20. Maltais F, Simard A, Simard C, Jobin J, Desganés P, Leblanc P. Oxidative capacity of the skeletal muscle and lactic acid kinetics during exercise in normal subjects and in patients with COPD. Am J Resp Crit Care Med. 1996;153:288-93.
21. Mattson JP, Poole DC. Pulmonary emphysema decreases hamster skeletal muscle oxidative enzyme capacity. J Appl Physiol. 1998;85:210-4.
22. Meyer T, Georg T, Becker C, Kindermann W. Reliability of gas exchange measurement from two different spiroergometry systems. Int J Sports Med. 2001;22:593-7.
23. Middlekauff HR, Nitzsche EU, Hoh CK, Hamilton MA, Hage A, Moriguchi JD. Exaggerated renal vasoconstriction during exercise in heart failure patients. Circulation. 2000;101:784-9.
24. Negrão CE, Rondin MU, Tinucci T, et al. Abnormal neurovascular control during exercise is linked to heart failure severity. Am J Physiol. 2001;208:H1286-92.
25. Rabe KF, Hurd S, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of COPD - 2006 update. Am J Respir Crit Care Med. 2007;176:532-55.
26. Roseguini BT, Alvez CN, Chiappa GR, Stein R, Ribeiro JP. Muscle metaboreflex contribution to resting limb haemodynamic control is preserved in older subjects. Clin Physiol Funct Imaging. 2007;27:335-9.
27. Rowell LB, O'Leary DS. Reflex control of the circulation during exercise: chemoreflexes and mechanoreflexes. J Appl Physiol. 1990;69:407-18.
28. Seals DR. Sympathetic neural discharge and vascular resistance during exercise in humans. J Appl Physiol. 1989;66:2472-8.
29. Seals DR, Dinenno FA. Collateral damage: cardiovascular consequences of chronic sympathetic activation with human aging. Am J Physiol. 2004;287:H1895-905.
30. Sheriff DD, Augstyniak RA, O'Leary DS. Muscle chemoreflexinduced increases in right atrial pressure. Am J Physiol. 1998;275:H767-75.
31. Sinoway L, Prophet S, Gorman I, et al. Muscle acidosis during static exercise is associated with calf vasoconstriction. J Appl Physiol. 1989;66:429-36.
32. Tahawi Z, Orolinova N, Joshua IG, Bader M, Fletcher EC. Altered vascular reactivity in arterioles of chronic intermittent hypoxic rats. J Appl Physiol. 2001;90:2007-13.
33. Thijssen DH, Bleeker MWK, Smits P, Hopman MTE. Reproducibility of blood flow and pos-reactive hyperemia as measured by venous occlusion plethismography. Clin Sci. 2005;108:151-7.
34. Van Helvoort H, Van De Pol M, Heijdra Y, Dekhuijzen PN. Systemic inflammatory response to exhaustive exercise in patients with chronic obstructive pulmonary disease. Respir Med. 2005;99:1555-67.