메뉴 건너뛰기




Volumn 16, Issue 4, 2006, Pages 367-377

Targeting the Epigenome for the Treatment of Thoracic Malignancies

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; FLAVOPIRIDOL; FR 901228; HISTONE DEACETYLASE INHIBITOR;

EID: 37849189063     PISSN: 15474127     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thorsurg.2006.07.005     Document Type: Review
Times cited : (5)

References (67)
  • 2
    • 34247583482 scopus 로고    scopus 로고
    • Nonsmall cell lung cancer
    • DeVita V.T., Hellman S., and Rosenberg S.A. (Eds), Lippincott Williams & Wilkins, Philadelphia
    • Schrump D.S., Altorki N.K., Henschke C.I., et al. Nonsmall cell lung cancer. In: DeVita V.T., Hellman S., and Rosenberg S.A. (Eds). Cancer: principles & practice of oncology. 7th edition (2005), Lippincott Williams & Wilkins, Philadelphia 753-810
    • (2005) Cancer: principles & practice of oncology. 7th edition , pp. 753-810
    • Schrump, D.S.1    Altorki, N.K.2    Henschke, C.I.3
  • 3
    • 37949024411 scopus 로고    scopus 로고
    • Peto R. Influence of dose and duration of smoking on lung cancer rates. In: Zaridze D, Peto R, editors. Tobacco: a major international health hazard. Proceedings of an internal meeting, Moscow, USSR, June 4-6, 1985. International Agency for Research on Cancer Science Publication No. 74. Lyon (France): World Health Organization, International Agency for Research on Cancer; 1986. p. 23-33.
  • 4
    • 0034609239 scopus 로고    scopus 로고
    • Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of national statistics with two case-control studies
    • Peto R., Darby S., Deo H., et al. Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of national statistics with two case-control studies. BMJ 321 (2000) 323-329
    • (2000) BMJ , vol.321 , pp. 323-329
    • Peto, R.1    Darby, S.2    Deo, H.3
  • 5
    • 19844373387 scopus 로고    scopus 로고
    • Epidemiology of lung cancer: looking to the future
    • Alberg A.J., Brock M.V., and Samet J.M. Epidemiology of lung cancer: looking to the future. J Clin Oncol 23 (2005) 3175-3185
    • (2005) J Clin Oncol , vol.23 , pp. 3175-3185
    • Alberg, A.J.1    Brock, M.V.2    Samet, J.M.3
  • 6
    • 19844380785 scopus 로고    scopus 로고
    • New developments in lung cancer screening
    • Mulshine J.L. New developments in lung cancer screening. J Clin Oncol 23 (2005) 3198-3202
    • (2005) J Clin Oncol , vol.23 , pp. 3198-3202
    • Mulshine, J.L.1
  • 7
    • 19844371226 scopus 로고    scopus 로고
    • Advances in the biology of lung cancer chemoprevention
    • Hirsch F.R., and Lippman S.M. Advances in the biology of lung cancer chemoprevention. J Clin Oncol 23 (2005) 3186-3197
    • (2005) J Clin Oncol , vol.23 , pp. 3186-3197
    • Hirsch, F.R.1    Lippman, S.M.2
  • 8
    • 19844380235 scopus 로고    scopus 로고
    • Genomic and proteomic profiling of lung cancers: lung cancer classification in the age of targeted therapy
    • Meyerson M., and Carbone D. Genomic and proteomic profiling of lung cancers: lung cancer classification in the age of targeted therapy. J Clin Oncol 23 (2005) 3219-3226
    • (2005) J Clin Oncol , vol.23 , pp. 3219-3226
    • Meyerson, M.1    Carbone, D.2
  • 9
    • 0035045178 scopus 로고    scopus 로고
    • Targets for molecular intervention in multistep pulmonary carcinogenesis
    • Schrump D.S., and Nguyen D.M. Targets for molecular intervention in multistep pulmonary carcinogenesis. World J Surg 25 (2001) 174-183
    • (2001) World J Surg , vol.25 , pp. 174-183
    • Schrump, D.S.1    Nguyen, D.M.2
  • 10
    • 31444437920 scopus 로고    scopus 로고
    • Epigenetics provides a new generation of oncogenes and tumour-suppressor genes
    • Esteller M. Epigenetics provides a new generation of oncogenes and tumour-suppressor genes. Br J Cancer 94 (2006) 179-183
    • (2006) Br J Cancer , vol.94 , pp. 179-183
    • Esteller, M.1
  • 11
    • 33746091748 scopus 로고    scopus 로고
    • Epigenetics: the science of change
    • Weinhold B. Epigenetics: the science of change. Environ Health Perspect 114 (2006) A160-A167
    • (2006) Environ Health Perspect , vol.114
    • Weinhold, B.1
  • 12
    • 0036733675 scopus 로고    scopus 로고
    • Chromatin modification and epigenetic reprogramming in mammalian development
    • Li E. Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet 3 (2002) 662-673
    • (2002) Nat Rev Genet , vol.3 , pp. 662-673
    • Li, E.1
  • 13
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
    • Jaenisch R., and Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 33 (2003) 245-254
    • (2003) Nat Genet , vol.33 , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 14
    • 23644436275 scopus 로고    scopus 로고
    • Histone modifications as key regulators of transcription
    • Khan A.U., and Krishnamurthy S. Histone modifications as key regulators of transcription. Front Biosci 10 (2005) 866-872
    • (2005) Front Biosci , vol.10 , pp. 866-872
    • Khan, A.U.1    Krishnamurthy, S.2
  • 15
    • 9744251005 scopus 로고    scopus 로고
    • Biochemistry and biology of mammalian DNA methyltransferases
    • Hermann A., Gowher H., and Jeltsch A. Biochemistry and biology of mammalian DNA methyltransferases. Cell Mol Life Sci 61 (2004) 2571-2587
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2571-2587
    • Hermann, A.1    Gowher, H.2    Jeltsch, A.3
  • 16
    • 0032890965 scopus 로고    scopus 로고
    • The DNA methylation paradox
    • Jones P.A. The DNA methylation paradox. Trends Genet 15 (1999) 34-37
    • (1999) Trends Genet , vol.15 , pp. 34-37
    • Jones, P.A.1
  • 17
    • 24344466882 scopus 로고    scopus 로고
    • DNA methylation and histone modifications: teaming up to silence genes
    • Fuks F. DNA methylation and histone modifications: teaming up to silence genes. Curr Opin Genet Dev 15 (2005) 490-495
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 490-495
    • Fuks, F.1
  • 18
    • 23044500926 scopus 로고    scopus 로고
    • Linking covalent histone modifications to epigenetics: the rigidity and plasticity of the marks
    • Wang Y., Wysocka J., Perlin J.R., et al. Linking covalent histone modifications to epigenetics: the rigidity and plasticity of the marks. Cold Spring Harb Symp Quant Biol 69 (2004) 161-169
    • (2004) Cold Spring Harb Symp Quant Biol , vol.69 , pp. 161-169
    • Wang, Y.1    Wysocka, J.2    Perlin, J.R.3
  • 19
    • 0042568929 scopus 로고    scopus 로고
    • Wellcome Trust Award Lecture. Chromatin-modifying enzymes in transcription and cancer
    • Kouzarides T. Wellcome Trust Award Lecture. Chromatin-modifying enzymes in transcription and cancer. Biochem Soc Trans 31 (2003) 741-743
    • (2003) Biochem Soc Trans , vol.31 , pp. 741-743
    • Kouzarides, T.1
  • 20
    • 0035839057 scopus 로고    scopus 로고
    • The role of DNA methylation in mammalian epigenetics
    • Jones P.A., and Takai D. The role of DNA methylation in mammalian epigenetics. Science 293 (2001) 1068-1070
    • (2001) Science , vol.293 , pp. 1068-1070
    • Jones, P.A.1    Takai, D.2
  • 21
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
    • Cameron E.E., Bachman K.E., Myohanen S., et al. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 21 (1999) 103-107
    • (1999) Nat Genet , vol.21 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3
  • 22
    • 24744456138 scopus 로고    scopus 로고
    • Targeting the epigenome for the treatment and prevention of lung cancer
    • Schrump D.S., and Nguyen D.M. Targeting the epigenome for the treatment and prevention of lung cancer. Semin Oncol 32 (2005) 488-502
    • (2005) Semin Oncol , vol.32 , pp. 488-502
    • Schrump, D.S.1    Nguyen, D.M.2
  • 23
    • 26444573127 scopus 로고    scopus 로고
    • Towards the human cancer epigenome: a first draft of histone modifications
    • Fraga M.F., and Esteller M. Towards the human cancer epigenome: a first draft of histone modifications. Cell Cycle 4 (2005) 1377-1381
    • (2005) Cell Cycle , vol.4 , pp. 1377-1381
    • Fraga, M.F.1    Esteller, M.2
  • 24
    • 13844320649 scopus 로고    scopus 로고
    • Aberrant DNA methylation as a cancer-inducing mechanism
    • Esteller M. Aberrant DNA methylation as a cancer-inducing mechanism. Annu Rev Pharmacol Toxicol 45 (2005) 629-656
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 629-656
    • Esteller, M.1
  • 25
    • 24744448032 scopus 로고    scopus 로고
    • Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells
    • Hong J.A., Kang Y., Abdullaev Z., et al. Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells. Cancer Res 65 (2005) 7763-7774
    • (2005) Cancer Res , vol.65 , pp. 7763-7774
    • Hong, J.A.1    Kang, Y.2    Abdullaev, Z.3
  • 26
    • 24744440159 scopus 로고    scopus 로고
    • Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes
    • Vatolin S., Abdullaev Z., Pack S.D., et al. Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes. Cancer Res 65 (2005) 7751-7762
    • (2005) Cancer Res , vol.65 , pp. 7751-7762
    • Vatolin, S.1    Abdullaev, Z.2    Pack, S.D.3
  • 27
    • 33645786274 scopus 로고    scopus 로고
    • Cancer testis antigens-their importance in immunotherapy and in the early detection of cancer
    • Suri A. Cancer testis antigens-their importance in immunotherapy and in the early detection of cancer. Expert Opin Biol Ther 6 (2006) 379-389
    • (2006) Expert Opin Biol Ther , vol.6 , pp. 379-389
    • Suri, A.1
  • 28
    • 2442562190 scopus 로고    scopus 로고
    • Epigenetics in lung cancer: focus on progression and early lesions
    • Herman J.G. Epigenetics in lung cancer: focus on progression and early lesions. Chest 125 (2004) 119S-122S
    • (2004) Chest , vol.125
    • Herman, J.G.1
  • 29
    • 0037427808 scopus 로고    scopus 로고
    • Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer
    • Toyooka S., Maruyama R., Toyooka K.O., et al. Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer. Int J Cancer 103 (2003) 153-160
    • (2003) Int J Cancer , vol.103 , pp. 153-160
    • Toyooka, S.1    Maruyama, R.2    Toyooka, K.O.3
  • 30
    • 25844506345 scopus 로고    scopus 로고
    • Modulation of DNA methylation for the treatment and prevention of cCancer
    • Kelloff G.J., Hawk E., and Sigman C. (Eds), Humana Press, Totowa (NJ)
    • Schrump D.S. Modulation of DNA methylation for the treatment and prevention of cCancer. In: Kelloff G.J., Hawk E., and Sigman C. (Eds). Cancer chemoprevention, vol. 1: Promising cancer chemoprevention agents (2004), Humana Press, Totowa (NJ) 643-658
    • (2004) Cancer chemoprevention, vol. 1: Promising cancer chemoprevention agents , pp. 643-658
    • Schrump, D.S.1
  • 31
    • 27144509196 scopus 로고    scopus 로고
    • DNA methyltransferase inhibitors and the development of epigenetic cancer therapies
    • Lyko F., and Brown R. DNA methyltransferase inhibitors and the development of epigenetic cancer therapies. J Natl Cancer Inst 97 (2005) 1498-1506
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1498-1506
    • Lyko, F.1    Brown, R.2
  • 32
    • 22144461094 scopus 로고    scopus 로고
    • Mechanism of inhibition of DNA methyltransfers by cytidine analogs in cancer therapy
    • Gowher H., and Jeltsch A. Mechanism of inhibition of DNA methyltransfers by cytidine analogs in cancer therapy. Cancer Biol Ther 3 (2004) 1062-1068
    • (2004) Cancer Biol Ther , vol.3 , pp. 1062-1068
    • Gowher, H.1    Jeltsch, A.2
  • 33
    • 20144388727 scopus 로고    scopus 로고
    • Sequential 5-Aza 2'-deoxycytidine/depsipeptide FK228 treatment induces tissue factor pathway inhibitor 2 (TFPI-2) expression in cancer cells
    • Steiner F., Hong J., Fischette M., et al. Sequential 5-Aza 2'-deoxycytidine/depsipeptide FK228 treatment induces tissue factor pathway inhibitor 2 (TFPI-2) expression in cancer cells. Oncogene 24 (2005) 2386-2397
    • (2005) Oncogene , vol.24 , pp. 2386-2397
    • Steiner, F.1    Hong, J.2    Fischette, M.3
  • 34
    • 10744229438 scopus 로고    scopus 로고
    • Vaccine-induced CD4 + T cell responses to MAGE-3 protein in lung cancer patients
    • Atanackovic D., Altorki N.K., Stockert E., et al. Vaccine-induced CD4 + T cell responses to MAGE-3 protein in lung cancer patients. J Immunol 172 (2004) 3289-3296
    • (2004) J Immunol , vol.172 , pp. 3289-3296
    • Atanackovic, D.1    Altorki, N.K.2    Stockert, E.3
  • 35
    • 7444253937 scopus 로고    scopus 로고
    • *04 patients with metastatic melanoma using epitopes from the NY-ESO-1 antigen
    • *04 patients with metastatic melanoma using epitopes from the NY-ESO-1 antigen. J Immunother 27 (2004) 472-477
    • (2004) J Immunother , vol.27 , pp. 472-477
    • Khong, H.T.1    Yang, J.C.2    Topalian, S.L.3
  • 36
    • 2642673605 scopus 로고    scopus 로고
    • A survey of the humoral immune response of cancer patients to a panel of human tumor antigens
    • Stockert E., Jäger E., Chen Y.-T., et al. A survey of the humoral immune response of cancer patients to a panel of human tumor antigens. J Exp Med 187 (1998) 1349-1354
    • (1998) J Exp Med , vol.187 , pp. 1349-1354
    • Stockert, E.1    Jäger, E.2    Chen, Y.-T.3
  • 37
    • 0037343236 scopus 로고    scopus 로고
    • Tumor cyclooxygenase 2-dependent suppression of dendritic cell function
    • Sharma S., Stolina M., Yang S.C., et al. Tumor cyclooxygenase 2-dependent suppression of dendritic cell function. Clin Cancer Res 9 (2003) 961-968
    • (2003) Clin Cancer Res , vol.9 , pp. 961-968
    • Sharma, S.1    Stolina, M.2    Yang, S.C.3
  • 38
    • 0037312480 scopus 로고    scopus 로고
    • Increase of regulatory T cells in the peripheral blood of cancer patients
    • Wolf A.M., Wolf D., Steurer M., et al. Increase of regulatory T cells in the peripheral blood of cancer patients. Clin Cancer Res 9 (2003) 606-612
    • (2003) Clin Cancer Res , vol.9 , pp. 606-612
    • Wolf, A.M.1    Wolf, D.2    Steurer, M.3
  • 39
    • 23444454047 scopus 로고    scopus 로고
    • The epigenetic breakdown of cancer cells: from DNA methylation to histone modifications
    • Ballestar E., and Esteller M. The epigenetic breakdown of cancer cells: from DNA methylation to histone modifications. Prog Mol. Subcell Biol 38 (2005) 169-181
    • (2005) Prog Mol. Subcell Biol , vol.38 , pp. 169-181
    • Ballestar, E.1    Esteller, M.2
  • 40
    • 0029094704 scopus 로고
    • INK4 gene mediated by an adenovirus vector
    • INK4 gene mediated by an adenovirus vector. Cancer Res 55 (1995) 3250-3253
    • (1995) Cancer Res , vol.55 , pp. 3250-3253
    • Jin, X.1    Nguyen, D.2    Zhang, W.-W.3
  • 41
    • 0035126974 scopus 로고    scopus 로고
    • Sequential 5-Aza-2 deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1
    • Weiser T.S., Guo Z.S., Ohnmacht G.A., et al. Sequential 5-Aza-2 deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1. J Immunother 24 (2001) 151-161
    • (2001) J Immunother , vol.24 , pp. 151-161
    • Weiser, T.S.1    Guo, Z.S.2    Ohnmacht, G.A.3
  • 42
    • 0035132573 scopus 로고    scopus 로고
    • Induction of MAGE-3 expression in lung and esophageal cancer cells
    • Weiser T.S., Ohnmacht G.A., Guo Z.S., et al. Induction of MAGE-3 expression in lung and esophageal cancer cells. Ann Thorac Surg 71 (2001) 295-301
    • (2001) Ann Thorac Surg , vol.71 , pp. 295-301
    • Weiser, T.S.1    Ohnmacht, G.A.2    Guo, Z.S.3
  • 43
    • 0027478361 scopus 로고
    • Identification of human cancers deficient in antigen processing
    • Restifo N.P., Esquivel F., Kawakami Y., et al. Identification of human cancers deficient in antigen processing. J Exp Med 177 (1993) 265-272
    • (1993) J Exp Med , vol.177 , pp. 265-272
    • Restifo, N.P.1    Esquivel, F.2    Kawakami, Y.3
  • 44
    • 31544432509 scopus 로고    scopus 로고
    • De novo iInduction of a cancer/testis antigen by 5-Aza-2'-deoxycytidine augments adoptive immunotherapy in a murine tumor model
    • Guo Z.S., Hong J.A., Irvine K.R., et al. De novo iInduction of a cancer/testis antigen by 5-Aza-2'-deoxycytidine augments adoptive immunotherapy in a murine tumor model. Cancer Res 66 (2006) 1105-1113
    • (2006) Cancer Res , vol.66 , pp. 1105-1113
    • Guo, Z.S.1    Hong, J.A.2    Irvine, K.R.3
  • 45
    • 0031767121 scopus 로고    scopus 로고
    • The shared tumor-specific antigen encoded by mouse gene P1A is a target not only for cytolytic T lymphocytes but also for tumor rejection
    • Brandle D., Bilsborough J., Rulicke T., et al. The shared tumor-specific antigen encoded by mouse gene P1A is a target not only for cytolytic T lymphocytes but also for tumor rejection. Eur J Immunol 28 (1998) 4010-4019
    • (1998) Eur J Immunol , vol.28 , pp. 4010-4019
    • Brandle, D.1    Bilsborough, J.2    Rulicke, T.3
  • 46
    • 31044451642 scopus 로고    scopus 로고
    • Depletion of DNA methyltransferase (DNMT)1, and/or DNMT3b mediates growth arrest and apoptosis in cultured thoracic malignancies
    • Kassis E.M., Zhao M., Hong J.A., et al. Depletion of DNA methyltransferase (DNMT)1, and/or DNMT3b mediates growth arrest and apoptosis in cultured thoracic malignancies. J Thorac Cardiovasc Surg 131 (2006) 298-306
    • (2006) J Thorac Cardiovasc Surg , vol.131 , pp. 298-306
    • Kassis, E.M.1    Zhao, M.2    Hong, J.A.3
  • 47
    • 0038341137 scopus 로고    scopus 로고
    • Epigenomic stress response. Knockdown of DNA methyltransferase 1 triggers an intra-S-phase arrest of DNA replication and induction of stress response genes
    • Milutinovic S., Zhuang Q., Niveleau A., et al. Epigenomic stress response. Knockdown of DNA methyltransferase 1 triggers an intra-S-phase arrest of DNA replication and induction of stress response genes. J Biol Chem 278 (2003) 14985-14995
    • (2003) J Biol Chem , vol.278 , pp. 14985-14995
    • Milutinovic, S.1    Zhuang, Q.2    Niveleau, A.3
  • 48
    • 0028151343 scopus 로고
    • Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
    • Juttermann R., Li E., and Jaenisch R. Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc Natl Acad Sci USA 91 (1994) 11797-11801
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11797-11801
    • Juttermann, R.1    Li, E.2    Jaenisch, R.3
  • 49
    • 1842481018 scopus 로고    scopus 로고
    • Abrogation of p21 expression by flavopiridol enhances depsipeptide-mediated apoptosis in malignant pleural mesothelioma cells
    • Nguyen D.M., Schrump W.D., Chen G.A., et al. Abrogation of p21 expression by flavopiridol enhances depsipeptide-mediated apoptosis in malignant pleural mesothelioma cells. Clin Cancer Res 10 (2004) 1813-1825
    • (2004) Clin Cancer Res , vol.10 , pp. 1813-1825
    • Nguyen, D.M.1    Schrump, W.D.2    Chen, G.A.3
  • 50
    • 0037012344 scopus 로고    scopus 로고
    • Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228
    • Yu X., Guo Z.S., Marcu M.G., et al. Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228. J Natl Cancer Inst 94 (2002) 504-513
    • (2002) J Natl Cancer Inst , vol.94 , pp. 504-513
    • Yu, X.1    Guo, Z.S.2    Marcu, M.G.3
  • 51
    • 0033502429 scopus 로고    scopus 로고
    • Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity
    • Neckers L., Schulte T.W., and Mimnaugh E. Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity. Invest New Drugs 17 (1999) 361-373
    • (1999) Invest New Drugs , vol.17 , pp. 361-373
    • Neckers, L.1    Schulte, T.W.2    Mimnaugh, E.3
  • 52
    • 37949004101 scopus 로고    scopus 로고
    • Yu X, Yang Y, Chen GA, et al. Apoptosis induced by depsipeptide FK228 coincides with inhibition of EGFR-mediated survival signaling in lung cancer cells. Lung Cancer, in press.
  • 53
    • 0031725137 scopus 로고    scopus 로고
    • Flavopiridol mediates cell cycle arrest and apoptosis in esophageal cancer cells
    • Schrump D.S., Matthews W., Chen G.A., et al. Flavopiridol mediates cell cycle arrest and apoptosis in esophageal cancer cells. Clin Cancer Res 4 (1998) 2885-2890
    • (1998) Clin Cancer Res , vol.4 , pp. 2885-2890
    • Schrump, D.S.1    Matthews, W.2    Chen, G.A.3
  • 54
    • 0035108978 scopus 로고    scopus 로고
    • Strategies to circumvent SV40 oncoprotein expression in malignant pleural mesotheliomas
    • Schrump D.S., and Waheed I. Strategies to circumvent SV40 oncoprotein expression in malignant pleural mesotheliomas. Semin Cancer Biol 11 (2001) 73-80
    • (2001) Semin Cancer Biol , vol.11 , pp. 73-80
    • Schrump, D.S.1    Waheed, I.2
  • 55
    • 0033371777 scopus 로고    scopus 로고
    • Strategies for molecular intervention in esophageal cancers and their precursor lesions
    • Schrump D.S., and Nguyen D.M. Strategies for molecular intervention in esophageal cancers and their precursor lesions. Dis Esophagus 12 (1999) 181-185
    • (1999) Dis Esophagus , vol.12 , pp. 181-185
    • Schrump, D.S.1    Nguyen, D.M.2
  • 56
    • 0037674946 scopus 로고    scopus 로고
    • Enhancement of depsipeptide-mediated apoptosis of lung or esophageal cancer cells by flavopiridol: activation of the mitochondria-dependent death-signaling pathway
    • Nguyen D.M., Schrump W.D., Tsai W.S., et al. Enhancement of depsipeptide-mediated apoptosis of lung or esophageal cancer cells by flavopiridol: activation of the mitochondria-dependent death-signaling pathway. J Thorac Cardiovasc Surg 125 (2003) 1132-1142
    • (2003) J Thorac Cardiovasc Surg , vol.125 , pp. 1132-1142
    • Nguyen, D.M.1    Schrump, W.D.2    Tsai, W.S.3
  • 57
    • 0036594890 scopus 로고    scopus 로고
    • The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
    • Gartel A.L., and Tyner A.L. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol Cancer Ther 1 (2002) 639-649
    • (2002) Mol Cancer Ther , vol.1 , pp. 639-649
    • Gartel, A.L.1    Tyner, A.L.2
  • 58
    • 37949056575 scopus 로고    scopus 로고
    • Rebbaa A, Zheng X, Chu F, et al. The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis. Cell Death Differ, in press.
  • 59
    • 0034900178 scopus 로고    scopus 로고
    • A phase II trial of the cyclin-dependent kinase inhibitor flavopiridol in patients with previously untreated stage IV non-small cell lung cancer
    • Shapiro G.I., Supko J.G., Patterson A., et al. A phase II trial of the cyclin-dependent kinase inhibitor flavopiridol in patients with previously untreated stage IV non-small cell lung cancer. Clin Cancer Res 7 (2001) 1590-1599
    • (2001) Clin Cancer Res , vol.7 , pp. 1590-1599
    • Shapiro, G.I.1    Supko, J.G.2    Patterson, A.3
  • 60
    • 22244467085 scopus 로고    scopus 로고
    • Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner
    • Krysan K., Reckamp K.L., Dalwadi H., et al. Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. Cancer Res 65 (2005) 6275-6281
    • (2005) Cancer Res , vol.65 , pp. 6275-6281
    • Krysan, K.1    Reckamp, K.L.2    Dalwadi, H.3
  • 61
    • 0346368096 scopus 로고    scopus 로고
    • Targeting cyclooxygenase-2 in human neoplasia: rationale and promise
    • Dannenberg A.J., and Subbaramaiah K. Targeting cyclooxygenase-2 in human neoplasia: rationale and promise. Cancer Cell 4 (2003) 431-436
    • (2003) Cancer Cell , vol.4 , pp. 431-436
    • Dannenberg, A.J.1    Subbaramaiah, K.2
  • 62
    • 3543050046 scopus 로고    scopus 로고
    • Multifaceted roles of cyclooxygenase-2 in lung cancer
    • Riedl K., Krysan K., Pold M., et al. Multifaceted roles of cyclooxygenase-2 in lung cancer. Drug Resist Updat 7 (2004) 169-184
    • (2004) Drug Resist Updat , vol.7 , pp. 169-184
    • Riedl, K.1    Krysan, K.2    Pold, M.3
  • 63
    • 0042631411 scopus 로고    scopus 로고
    • Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer
    • Altorki N.K., Keresztes R.S., Port J.L., et al. Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer. J Clin Oncol 21 (2003) 2645-2650
    • (2003) J Clin Oncol , vol.21 , pp. 2645-2650
    • Altorki, N.K.1    Keresztes, R.S.2    Port, J.L.3
  • 64
    • 20444464066 scopus 로고    scopus 로고
    • Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4 + CD25 + T regulatory cell activities in lung cancer
    • Sharma S., Yang S.C., Zhu L., et al. Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4 + CD25 + T regulatory cell activities in lung cancer. Cancer Res 65 (2005) 5211-5220
    • (2005) Cancer Res , vol.65 , pp. 5211-5220
    • Sharma, S.1    Yang, S.C.2    Zhu, L.3
  • 65
    • 23244437041 scopus 로고    scopus 로고
    • Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses
    • Sharma S., Zhu L., Yang S.C., et al. Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses. J Immunol 175 (2005) 813-819
    • (2005) J Immunol , vol.175 , pp. 813-819
    • Sharma, S.1    Zhu, L.2    Yang, S.C.3
  • 66
    • 2442686929 scopus 로고    scopus 로고
    • Combination of a poxvirus-based vaccine with a cyclooxygenase-2 inhibitor (celecoxib) elicits antitumor immunity and long-term survival in CEA.Tg/MIN mice
    • Zeytin H.E., Patel A.C., Rogers C.J., et al. Combination of a poxvirus-based vaccine with a cyclooxygenase-2 inhibitor (celecoxib) elicits antitumor immunity and long-term survival in CEA.Tg/MIN mice. Cancer Res 64 (2004) 3668-3678
    • (2004) Cancer Res , vol.64 , pp. 3668-3678
    • Zeytin, H.E.1    Patel, A.C.2    Rogers, C.J.3
  • 67
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
    • Albert M.L., Sauter B., and Bhardwaj N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392 (1998) 86-89
    • (1998) Nature , vol.392 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.