Characterization of carbadox-induced mutagenesis using a shuttle vector pSP189 in mammalian cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 638, Issue 1-2, 2008, Pages 11-16

  Chen, Qian ^a   Chen, Yiqiang ^a   Qi, Yitao ^a   Hao, Lihua ^a   Tang, Shusheng ^a   Xiao, Xilong ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Carbadox; Mutagenicity; Shuttle vector plasmid pSP189; Vero cells

Indexed keywords

CARBADOX; PLASMID DNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; DOSE RESPONSE; DRUG EFFECT; ESCHERICHIA COLI; GENE AMPLIFICATION; GENE FREQUENCY; GENE MUTATION; GENE REPLICATION; GENE SEQUENCE; GENE TARGETING; IN VITRO STUDY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; SHUTTLE VECTOR; SUPF GENE; SUPPRESSOR GENE;

ANIMALS; ANTI-INFECTIVE AGENTS; BASE SEQUENCE; CARBADOX; CERCOPITHECUS AETHIOPS; GENES, SUPPRESSOR; GENETIC VECTORS; MOLECULAR SEQUENCE DATA; MUTAGENICITY TESTS; MUTAGENS; RNA, TRANSFER; TRANSFECTION; VERO CELLS;

ANIMALIA; ESCHERICHIA COLI; MAMMALIA;

EID: 37849028998     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2007.08.006     Document Type: Article

References (22)

1. Yoshimura H., Nakmura M., and Koeda T. Mutagenicities of carbadox and olaquindox: growth promoters for pigs. Mutat. Res. 90 (1981) 49-55
2. Oud J.L., Reutlinger A.H., and Branger J. An investigation into the cytogenetic damage induced by the coccidiostatic agents amprolium, carbadox, dimetridazole and ronidazole. Mutat. Res. 68 (1979) 179-182
3. Cihak R., and Vontorkova M. Cytogenetic effects of quinoxaline-1,4-dioxide-type growth-promoting agents. II. Metaphase analysis in mice. Mutat. Res. 117 (1983) 311-316
4. Yoshimura H. Teratogenic assessment of carbadox in rats. Toxicol. Lett. 129 (2002) 115-118
5. Scheutwinkel-Reich M., and Vd Hude W. Sister-chromatid exchange in Chinese hamster V79 cells exposed to quindoxin, carbadox and olaquindox. Mutat. Res. 139 (1984) 199-202
6. Ohta T., Moriya M., Kaneda Y., et al. Mutagenicity screening of feed additives in the microbial system. Mutat. Res. 77 (1980) 21-30
7. Tucker M.J. Carcinogenic action of quinoxaline 1,4-dioxide in rat. J. Natl. Cancer Inst. 55 1 (1975) 137-140
8. Nabuurs M.J.A., Van Der Molen E.J., De Graaf G.J., et al. Clinical signs and performance of pigs treated with different levels of carbadox, cyadox and olaquindox. J. Vet. Med. 37 (1989) 209-217
9. Commission of the European Communities, Commission Regulation 2788/98, Off. J. Eur. Communities: Legis. L347 (1998), p. 32.
10. Botsoglou N.A., and Fletouris D.J. Drug Residues in Foods: Pharmacology, Food Safety and Analysis (2001), Marcel Dekker, New York (chapter 6)
11. Seidman M.M., Dixon K., and Razzaque A. A shuttle vector plasmid for string carcinogen-induced point mutations in mammalian cells. Gene 38 (1985) 233-238
12. Mudipalli A., Nadadur S.S., and Maccubbin A.E. Mutations induced by decarbazine activated with cytochrome P-450. Mutat. Res. 327 (1995) 113-120
13. Murata-Kamiya N., Kamiyab H., Kajia H., et al. Methylglyoxal induces G:C to C:G and G:C to T:A transversions in the supF gene on a shuttle vector plasmid replicated in mammalian cells. Mutat. Res. 468 (2000) 173-182
14. Rossman T.G., Meyer L.W., Butler J.P., and Daisey J.M. Use of the microscreen assay for airborne particulate organic matter. In: Waters M.D., Sandhu S.S., Lewtas J., Claxton L., Strauss G., and Nesnows S. (Eds). Short-Term Bioassays in Analysis of Complex Environmental Mixtures IV (1985), Plenum, NewYork 9-23
15. Hao L.H., Chen Q., and Xiao X.L. Molecular mechanism of mutagenesis induced by olaquindox using a shuttle vector pSP189/mammalian cell system. Mutat. Res. 599 (2006) 21-25
16. Nakano T., Okaichi K., Harada K., et al. Mutations of a shuttle vector plasmid, pZ189, in Escherichia coli induced by boron neutron captured beam (BNCB) containing alpha-particles. Mutat. Res. 336 (1995) 153-159
17. Juedes M.J., and Wogan G.N. Peroxynitrite-induced mutation spectra of pSP189 following replication in bacteria and in human cells. Mutat. Res. 349 (1996) 51-61
18. Tan X.Z.H., Li S.H.D., Luo X.Y., et al. Establishment of shuttle vector pSP189/vero E6 cell system and its application in the screening of mycotoxin mutagenicity. J. Hyg. Res. 25 6 (1996) 365-367
19. Canella K.A., and Seidman M.M. Mutation spectra in supF: approaches to elucidating sequence context effects. Mutat. Res. 450 (2000) 61-73
20. Czerny C., Eder E., and Rünger T.M. Genotoxicity and mutagenicity of the alpha, beta-unsaturated carbonyl compound crotonaldehyde (butenal) on a plasmid shuttle vector. Mutat. Res. 407 (1998) 125-134
21. Gaskell M., McLuckie K.I., and Farmer P.B. Comparison of the mutagenic activity of the benzene metabolites, hydroquinone and para-benzoquinone in the supF forward mutation assay: a role for minor DNA adducts formed from hydroquinone in benzene mutagenicity. Mutat. Res. 554 (2004) 387-398
22. Sram R.J., Fernandez Rodriquez S.F., and Kocisova J. Effect of long-term oral administration of cyadox and olaquindox on the frequency of dominant lethal mutations and sperm abnormalities in mice. Biol. Chem. Vet. (Prague) 22 (1986) 37-45