Alpha-ketoglutarate and N-acetyl cysteine protect PC12 cells from cyanide-induced cytotoxicity and altered energy metabolism

NeuroToxicology

Volumn 29, Issue 1, 2008, Pages 170-178

  Satpute, R M ^a   Hariharakrishnan, J ^a   Bhattacharya, R ^a  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

Author keywords

Alpha ketoglutarate; Cyanide; Cytotoxicity; Energy metabolism; N Acetylcysteine; PC12 cells; Protection

Indexed keywords

2 OXOGLUTARIC ACID; ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; CALCIUM; CYANIDE; LACTIC ACID; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CELL PROTECTION; CELL RESPIRATION; CELL STRAIN; CHROMOSOME PAIRING; CONTROLLED STUDY; CYANIDE POISONING; CYTOTOXICITY; ENERGY METABOLISM; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

ACETYLCYSTEINE; ANIMALS; CALCIUM; CELL SURVIVAL; CYANATES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENERGY METABOLISM; FREE RADICAL SCAVENGERS; KETOGLUTARIC ACIDS; LACTIC ACID; PC12 CELLS; PEROXIDES; RATS; TIME FACTORS;

RATTUS;

EID: 37849013880     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2007.10.009     Document Type: Article

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