Does the panel of cytokeratin 20 and androgen receptor antibodies differentiate desmoplastic trichoepithelioma from morpheaform/infiltrative basal cell carcinoma?

Journal of Cutaneous Pathology

Volumn 35, Issue 2, 2008, Pages 174-179

  Katona, Terrence M ^a   Perkins, Susan M ^a   Billings, Steven D ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANTIBODY; CYTOKERATIN 20;

ARTICLE; BASAL CELL CARCINOMA; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; IMMUNOREACTIVITY; MERKEL CELL; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY; TRICHOEPITHELIOMA;

CARCINOMA, BASAL CELL; DIAGNOSIS, DIFFERENTIAL; HUMANS; IMMUNOHISTOCHEMISTRY; KERATIN-20; NEOPLASMS, BASAL CELL; RECEPTORS, ANDROGEN; SKIN NEOPLASMS;

EID: 37849006377     PISSN: 03036987     EISSN: 16000560     Source Type: Journal    
DOI: 10.1111/j.1600-0560.2007.00783.x     Document Type: Article

References (16)

1. Brownstein MH, Shapiro L. Desmoplastic trichoepithelioma. Cancer 1977 40 : 2979.
2. Wang S-H, Tsai R-Y, Chi C-C. Familial desmoplastic trichoepithelioma. Int J Dermatol 2006 45 : 756.
3. Thewes M, Worret W-I, Engst R, Ring J. Stromelysin-3: a potent marker for histopathologic differentiation between desmoplastic trichoepithelioma and morhealike basal cell carcinoma. Am J Dermatopathol 1998 20 : 140.
4. Abesamis-Cubillan E, Shabrawi-Cailen L, LeBoit PE. Merkel cells and sclerosing epithelial neoplasms. Am J Dermatopathol 2000 22 : 311.
5. Bayer-Garner I, Givens V, Smoller B. Immunohistochemical staining for androgen receptors: a sensitive marker of sebaceous differentiation. Am J Dermatopathol 1999 21 : 426.
6. Gao W, Bohl C, Dalton J. Chemistry and structural biology of androgen receptor. Chem Rev 2005 105 : 3352.
7. Izikson L, Bhan A, Zembowicz A. Androgen receptor expression helps to differentiate basal cell carcinoma from benign trichoblastic tumors. Am J Dermatopathol 2005 27 : 91.
8. Katona TM, Ravis SM, Perkins SM, Moores WB, Billings SD. Expression of androgen receptor by fibroepithelioma of Pinkus - evidence supporting classification as a basal cell carcinoma variant? Am J Dermatopathol 2007 29 : 7.
9. Hartschuh W, Schulz T. Merkel cells are integral constituents of desmoplastic trichoepithelioma: an immunohistochemical and electron microscopic study. Am J Dermatopathol 1995 21 : 8.
10. Mahmoodi M, Asad H, Salim S, Kantor G, Minimo C. Anti-cytokeratin 20 staining of Merkel cells helps differentiate basaloid proliferations overlying dermatofibromas from basal cell carcinoma. J Cutan Pathol 2005 32 : 491.
11. Schulz T, Hartscuh W. Merkel cells are absent in basal cell carcinomas but frequently found in trichoblastomas. An immunohistochemical study. J Cutan Pathol 1997 24 : 14.
12. McNiff J, Eisen R, Glusac E. Immunohistochemical comparison of cutaneous lymphadenoma, trichoblastoma, and basal cell carcinoma: support for classification of lymphadenoma as a variant of trichoblastoma. J Cutan Pathol 1999 26 : 119.
13. Katona TM, Billings SD, Montironi R, Lopez-Beltran A, Cheng L. Expression of OCT4 transcription factor in cutaneous neoplasia. Appl Immunohistochem Mol Morphol 2006 in press.
14. Katona TM, Neubauer BL, Iversen PD, Zhang S, Baldridge LA, Cheng L. Elevated expression of angiogenin in prostate cancer and its precursors. Clin Cancer Res 2005 11 : 8358.
15. Cheng L, Zincke H, Blute M, Bergstralh E, Scherer B, Bostwick D. Risk of prostate carcinoma death in patients with lymph node metastasis. Cancer 2001 91 : 66.
16. Takei Y, Fukushiro S, Ackerman AB. Criteria for histologic differentiation of desmoplastic trichoepithelioma (sclerosing epithelial hamartoma) from morphea-like basal-cell carcinoma. Am J Dermatopathol 1985 7 : 207.