Pregnancy in carriers of haemophilia

Haemophilia

Volumn 14, Issue 1, 2008, Pages 56-64

  Chi, C ^a   Lee, C A ^a   Shiltagh, N ^a   Khan, A ^a   Pollard, D ^a   Kadir, R A ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

Carriers of haemophilia; Postpartum haemorrhage; Prenatal diagnosis

Indexed keywords

ANTIBIOTIC AGENT; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; CARBOPROST; OXYTOCIN; RECOMBINANT BLOOD CLOTTING FACTOR 8; RECOMBINANT BLOOD CLOTTING FACTOR 9; TRANEXAMIC ACID; VITAMIN K GROUP;

CESAREAN SECTION; CHILDBIRTH; CHROMOSOME ABERRATION; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE CARRIER; FEMALE; HEMOPHILIA A; HEMOPHILIA B; HUMAN; INCIDENCE; INFANT; INSTRUMENTAL DELIVERY; INTRAPARTUM CARE; LIVE BIRTH; MAJOR CLINICAL STUDY; MALE; MANAGED CARE; NEONATAL HEMORRHAGE; OBSTETRIC CARE; POSTPARTUM HEMORRHAGE; PREGNANCY OUTCOME; PREGNANCY TERMINATION; PRENATAL SCREENING; PRIORITY JOURNAL; PUERPERAL INFECTION; RETROSPECTIVE STUDY; REVIEW; RISK ASSESSMENT; SEX DETERMINATION; SPONTANEOUS ABORTION; UNITED KINGDOM;

COHORT STUDIES; FEMALE; HEMOPHILIA A; HEMORRHAGE; HETEROZYGOTE; HUMANS; INFANT, NEWBORN; MALE; PRACTICE GUIDELINES AS TOPIC; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PREGNANCY OUTCOME; PRENATAL DIAGNOSIS; RETROSPECTIVE STUDIES;

EID: 37749037035     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/j.1365-2516.2007.01561.x     Document Type: Review

References (23)

1. Plug I, Mauser-Bunschoten EP, Brocker-Vriends AHJ et.al. Bleeding in carriers of hemophilia. Blood 2006; 108: 52-6.
2. Lyon MF. Sex chromatin and gene action in the mammalian X-chromosome. Am J Hum Genet 1962; 14: 135-48.
3. Lusher JM, McMillan CW. Severe factor VIII and factor IX deficiency in females. Am J Med 1978; 65: 637-48.
4. Kadir RA, Economides DL, Braithwaite J, Goldman E, Lee CA. The obstetric experience of carriers of haemophilia. BJOG 1997; 104: 803-10.
5. Chi C, Hyett JA, Finning KM, Lee CA, Kadir RA. Non-invasive first trimester determination of fetal gender: A new approach for prenatal diagnosis of haemophilia. BJOG 2006; 113: 239-42.
6. Clark P. Changes of hemostasis variables during pregnancy. Semin Vasc Med 2003; 3: 13-24.
7. Varekamp I, Suurmeijer TP, Brocker-Vriends AH et.al. Carrier testing and prenatal diagnosis for hemophilia; experiences and attitudes of 549 potential and obligate carriers. Am J Med Genet 1990; 37: 147-54.
8. Tedgard U, Ljung R, McNeil TF. Reproductive choices of haemophilia carriers. Br J Haematol 1999; 106: 421-6.
9. Beller FK, Ebert C. The coagulation and fibrinolytic enzyme system in pregnancy and in the puerperium. Eur J Obstet Gynecol Reprod Biol 1982; 13: 177-97.
10. Lee CA, Chi C, Pavord SR et.al. The obstetric and gynaecological management of women with inherited bleeding disorders -review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors'Organization. Haemophilia 2006; 12: 301-36.
11. Juul J, Lie B, Friberg Nielsen S. Epidural analgesia vs. general anesthesia for cesarean section. Acta Obstet Gynecol Scand 1998; 67: 203-6.
12. Lie B, Juul J. Effect of epidural vs. general anesthesia on breastfeeding. Acta Obstet Gynecol Scand 1988; 67: 207-9.
13. Evans CM, Murphy JF, Gray OP, Rosen M. Epidural versus general anaesthesia for elective caesarean section. Effect on Apgar score and acid-base status of the newborn. Anaesthesia 1989; 44: 778-82.
14. Dhar P, Abramovitz S, DiMichele D, Gibb CB, Gadalla F. Management of pregnancy in a patient with severe haemophilia A. Br J Anaesth 2003; 91: 432-5.
15. Abramovitz S, Beilin Y. Thrombocytopenia, low molecular weight heparin, and obstetric anesthesia. Anesth Clin N Am 2003; 21: 99-109.
16. Kulkarni R, Lusher J. Perinatal management of newborns with haemophilia. Br J Haematol 2001; 112: 264-74.
17. Klinge J, Auberger K, Auerswald G, Brackmann HH, Mauz-Korholz Ch, Kreuz W and The paediatric group of the German Society of Thrombosis and Haemostasis. Prevalence and outcome of intracranial haemorrhage in haemophiliacs -a survey of the paediatric group of the German Society of Thrombosis and Haemostasis (GTH). Eur J Pediatr 1999; 158 (Suppl. 3): S162-5.
18. Kulkarni R, Lusher JM. Intracranial and extracranial hemorrhages in newborns with haemophilia: A review of the literatures. J Pediatr Hematol Oncol 1999; 21: 289-95.
19. Ljung R, Lindgren AC, Petrini P, Tengborn L. Normal vaginal delivery is to be recommended for haemophilia carrier gravidae. Acta Paediatr 1994; 83: 609-11.
20. Michaud JL, Rivard GE, Chessex P. Intracranial hemorrhage in a newborn with hemophilia following elective cesarean section. Am J Pediatr Hematol Oncol 1991; 13: 473-5.
21. Van der Bom JG, Mauser-Bunschoten EP, Fischer K, Van den Berg HM. Age at first treatment and immune tolerance to factor VIII in severe hemophilia. Thromb Haemost 2003; 89: 475-9.
22. Royal College of Obstetricians and Gynaecologists Clinical Effectiveness Support Unit. National Sentinel Audit Report. London: RCOG Press, 2001.
23. Read MD, Anderton JM. Radioisotope dilution technique for measurement of blood loss associated with lower segment caesarean section. Br J Obstet Gynaecol 1977; 84: 859-61.