Electron crystallography of biomolecules: mysterious membranes and missing cones

Trends in Biochemical Sciences

Volumn 33, Issue 1, 2008, Pages 38-43

  Ford, Robert C ^a   Holzenburg, Andreas ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN; MEMBRANE PROTEIN;

BETA SHEET; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ELECTRON CRYSTALLOGRAPHY; IMAGE ANALYSIS; IMAGE DISPLAY; IMAGE QUALITY; LIPID BILAYER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ISOLATION; REVIEW; THREE DIMENSIONAL IMAGING; TRANSMISSION ELECTRON MICROSCOPY; X RAY CRYSTALLOGRAPHY;

ATP-BINDING CASSETTE TRANSPORTERS; CRYSTALLOGRAPHY; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI PROTEINS; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON; MICROSCOPY, ELECTRON, TRANSMISSION;

EID: 37749008623     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2007.10.002     Document Type: Review

References (24)

1. Gyobu N., et al. Improved specimen preparation for cryo-electron microscopy using a symmetric carbon sandwich technique. J. Struct. Biol. 146 (2004) 325-333
2. Gonen T., et al. Lipid-protein interactions in double-layered two-dimensional AQP0 crystals. Nature 438 (2005) 633-638
3. Drory O., and Nelson N. The emerging structure of vacuolar ATPases. Physiology (Bethesda) 21 (2006) 317-325
4. Clare D.K., et al. An expanded and flexible form of the vacuolar ATPase membrane sector. Structure 14 (2006) 1149-1156
5. Ziegler C., et al. Projection structure and oligomeric state of the osmoregulated sodium/glycine betaine symporter BetP of Corynebacterium glutamicum. J. Mol. Biol. 337 (2004) 1137-1147
6. Ubarretxena-Belandia I., et al. Three-dimensional structure of the bacterial multidrug transporter EmrE shows it is an asymmetric homodimer. EMBO J. 22 (2003) 6175-6181
7. Heymann J.A., et al. Projection structure of the bacterial oxalate transporter OxlT at 3.4A resolution. J. Struct. Biol. 144 (2003) 320-326
8. Purhonen P., et al. Three-dimensional structure of the sugar symporter melibiose permease from cryo-electron microscopy. J. Struct. Biol. 152 (2005) 76-83
9. Yin C.C., et al. Two-dimensional crystallization of the ryanodine receptor Ca2+ release channel on lipid membranes. J. Struct. Biol. 149 (2005) 219-224
10. Kunji E.R., and Harding M. Projection structure of the atractyloside-inhibited mitochondrial ADP/ATP carrier of Saccharomyces cerevisiae. J. Biol. Chem. 278 (2003) 36985-36988
11. Stuart M.C., et al. Mechanism of formation of multilayered 2D crystals of the enzyme IIC-mannitol transporter. Biochim. Biophys. Acta 1663 (2004) 108-116
12. Rosenberg M.F., et al. Three-dimensional structure of P-glycoprotein: the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state. J. Biol. Chem. 280 (2005) 2857-2862
13. Schmidt-Krey I., et al. Two-dimensional crystallization of human vitamin K-dependent gamma-glutamyl carboxylase. J. Struct. Biol. 157 (2007) 437-442
14. Vainshtein B.K. Structure Analysis by Electron Diffraction (1964), Pergamon Press
15. Hoppe W., and Hegerl R. Three-dimensional structure determination by electron microscopy (nonperiodic specimens). In: Hawkes P.W. (Ed). Computer Processing of Electron Microscope Images (1980), Springer 127-185
16. Amos L.A., et al. Three-dimensional structure determination by electron microscopy of two-dimensional crystals. Prog. Biophys. Mol. Biol. 39 (1982) 183-231
17. Glaeser R.M., et al. Three-dimensional reconstructions from incomplete data: interpretability of density maps at 'atomic' resolution. Ultramicroscopy 27 (1989) 307-318
18. Barth M., et al. Estimation of missing cone data in three-dimensional electron microscopy. Scanning Microsc. Suppl. 2 (1988) 277-284
19. Dorset D.L. Filling the missing cone in protein electron crystallography. Microsc. Res. Tech. 46 (1999) 98-103
20. Dorset D.L., and McCourt M.P. Electron crystallographic analysis of a polysaccharide structure-direct phase determination and model refinement for mannan I. J. Struct. Biol. 111 (1993) 118-124
21. Kimura Y., et al. Surface of bacteriorhodopsin revealed by high-resolution electron crystallography. Nature 389 (1997) 206-211
22. Dorset D.L., et al. Electron crystallography of zeolites - the MWW family as a test of direct 3D structure determination. Acta Crystallogr. A61 (2005) 516-527
23. Downing K.H. Automatic focus correction for spot-scan imaging of tilted specimens. Ultramicroscopy 46 (1992) 199-206
24. Locher K.P., et al. The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism. Science 296 (2002) 1091-1098