Association of the IFIH1-GCA-KCNH7 chromosomal region with rheumatoid arthritis [4]

Annals of the Rheumatic Diseases

Volumn 67, Issue 1, 2008, Pages 137-138

  Martinez A ^a   Varade J ^a   Lamas, J R ^a   Fernandez Arquero M ^a   Jover, J A ^a   De La Concha, E G ^a   Fernandez Gutierrez B ^a   Urcelay, Elena ^a  

^a HOSPITAL CLÍNICO SAN CARLOS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

VOLTAGE GATED POTASSIUM CHANNEL;

ADULT; AUTOIMMUNE DISEASE; CHROMOSOME; CONTROLLED STUDY; DISEASE COURSE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENOTYPE; HUMAN; LETTER; MELANOMA; ONSET AGE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ARTHRITIS, RHEUMATOID; CALCIUM-BINDING PROTEINS; CASE-CONTROL STUDIES; DEAD-BOX RNA HELICASES; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 37749001088     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2007.073213     Document Type: Letter

References (10)

1. Smyth DJ, Cooper JD, Bailey R, Field S, Burren O, Smink LJ, et al. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat Genet 2006;38:617-19.
2. Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, et al. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 2005;175:2851-8.
3. Saal JG, Steidle M, Einsele H, Mullet CA, Fritz P, Zacher J. Persistence of B19 parvovirus in synovial membranes of patients with rheumatoid arthritis. Rheumatol Int 1992;12:147-51.
4. Newkirk MM, Watanabe Duffy KN, Leclerc J, Lambert N, Shiroky JB. Detection of cytomegalovirus, Epstein-Barr virus and herpes virus-6 in patients with rheumatoid arthritis with or without Sjogren's syndrome. Rr J Rheumatol 1994;33:317-22.
5. Ollier W. Rheumatoid arthritis and Epstein-Barr virus: a case of living with the enemy? Ann Rheum Dis 2000;59:497-9.
6. Boyhan A, Casimir CM, French JK, Teahan CG, Segal AW. Molecular cloning and characterization of grancalcin, a novel EF-hand calcium-binding protein abundant in neutrophils and monocytes. J Biol Chem 1992;267:2928-33.
7. Liu F, Shinomiya H, Kirikae T, Hirata H, Asano Y. Characterization of murine grancalcin specifically expressed in leukocytes and its possible role in host defense against bacterial infection. Biosci Biotechnol Biochem 2004;68:894-902.
8. Roes J, Choi BK, Power D, Xu P, Segal AW. Granulocyte function in grancalcin-deficient mice. Mol Cell Biol 2003;23:826-30.
9. Cahalan MD, Wulff H, Chandy KG. Molecular properties and physiological roles of ion channels in the immune system. J Clin Immunol 2001;21:235-52.
10. Beeton C, Wulff H, Standifer NE, Azam P, Mullen KM, Pennington MW, et al. Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases. Proc Natl Acad Sci USA 2006;103:17414-19.