Microwave assisted ring-opening of epoxides with N-biaryl sulfonamides in the synthesis of matrix metalloproteinase-9 inhibitors

Tetrahedron Letters

Volumn 49, Issue 5, 2008, Pages 835-839

  Yang, Shyh Ming ^a   Murray, William V ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Epoxide; Matrix metalloproteinase; Microwave; MMP; Ring opening; Sulfonamide

Indexed keywords

ALKANESULFONAMIDE DERIVATIVE; EPOXIDE; GELATINASE B; GELATINASE INHIBITOR; SULFONAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICROWAVE RADIATION; RING OPENING; STRUCTURE ACTIVITY RELATION;

EID: 37649025655     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.11.184     Document Type: Article

References (17)

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