Determination of cytotoxicity of nephrotoxins on murine and human kidney cell lines

Journal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes

Volumn 43, Issue 1, 2008, Pages 71-74

  Park, Eun Kee ^a,b   Mak, Sally K ^a   Kültz, Dietmar ^a   Hammock, Bruce D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Research and Education Unit   (Australia)

Author keywords

HEK293 cells; Hyperosmolality; MIMCD3 cells; Paraquat

Indexed keywords

BIOLOGICAL ORGANS; CELLS;

HUMAN EMBRYONIC KIDNEY CELLS (HEK293); MIMCD3 CELLS; NEPHROTOXIC COMPOUNDS;

CYTOTOXICITY;

CISPLATIN; IBUPROFEN; PARAQUAT;

CELL ORGANELLE; TOXIC SUBSTANCE; TOXICITY; TOXIN;

ANIMAL; ARTICLE; CELL LINE; CELL SURVIVAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; HUMAN; KIDNEY; KIDNEY COLLECTING TUBULE; KIDNEY MEDULLA; LD 50; MOUSE; OSMOLARITY;

ANIMALS; CELL LINE; CELL SURVIVAL; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IBUPROFEN; KIDNEY; KIDNEY MEDULLA; KIDNEY TUBULES, COLLECTING; LETHAL DOSE 50; MICE; OSMOLAR CONCENTRATION; PARAQUAT;

MURINAE;

EID: 37649015339     PISSN: 03601234     EISSN: 15324109     Source Type: Journal    
DOI: 10.1080/03601230701735110     Document Type: Article

References (23)

1. Kintzel, P.E. Anticancer drug-induced kidney disorders. Drug Saf. 2001, 24 (1), 19-38.
2. Arany, I.; Safirstein, R.L. Cisplatin nephrotoxicity. Semin. Nephrol. 2003, 23 (5), 460-464.
3. Perazella, M.A. Drug-induced renal failure: Update on new medications and unique mechanisms of nephrotoxicity. Am. J. Med. Sci. 2003, 325 (6), 349-362.
4. Barbier, O.; Jacquillet, G.; Tauc, M.; Cougnon, M.; Poujeol, P. Effect of heavy metals on, and handling by, the kidney. Nephron Physiol. 2005, 99 (4), 105-110.
5. Rahman, A.; White, R.M. Cytotoxic anticancer agents and renal impairment study: The challenge remains. J. Clin. Oncol. 2006, 24 (4), 533-536.
6. Burg, M.B. Response of renal inner medullary epithelial cells to osmotic stress. Comp. Biochem. Physiol. Part A. Mol. Integr. Physiol. 2002, 133 (3), 661-666.
7. Lee, W.Y.; Jang, S.B.; Cha, S.H.; Lee, J.H.; Lee, K.H.; Kim, J.; Jo, Y.H.; Endou, H. Different sensitivity to nephrotoxic agents and osmotic stress in proximal tubular and collecting duct cell lines derived from transgenic mice. Toxicol. In Vitro 2002, 16 (1), 55-62.
8. Rocha, G.M.; Michea, L.F.; Peters, E.M.; Kirby, M.; Xu, Y.; Ferguson, D.R.; Burg, M.B. Direct toxicity of nonsteroidal antinflammatory drugs for renal medullary cells. Proc. Natl. Acad. Sci. USA 2001, 98 (9), 5317-5322.
9. Houze, P.; Baud, F.J.; Mouy, R.; Bismuth, C.; Bourdon, R.; Scherrmann, J.M. Toxicokinetics of paraquat in Humans. Human Exp. Toxicol. 1990, 9 (1), 5-12.
10. Mollman, J.E.; Glover, D.J.; Hogan, W.M.; Furman, R.E. Cisplatin neuropathy. Risk factors, prognosis, and protection by WR-2721. Cancer 1988, 61 (11), 2192-2195.
11. Gogas, H.; Shapiro, F.; Aghajanian, C.; Fennelly, D.; Almadrones, L.; Hoskins, W.J.; Spriggs, D.R. The impact of diabetes mellitus on the toxicity of therapy for advanced ovarian cancer. Gynecol. Oncol. 1996, 61 (1), 22-26.
12. Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65 (1-2), 55-63.
13. Carmichael, J.; Mitchell, J.B.; Degraff, W.G.; Gamson, J.; Gazdar, A.F.; Johnson, B.E.; Glatstein, E.; Minna, J.D. Chemosensitivity testing of human lung cancer cell lines using the MTT assay. Br. J. Cancer 1988, 57 (6), 540-547.
14. Arnould, R.; Dubios, J.; Abikhalil, F.; Libert, A.; Ghanem, G.; Atassi, G.; Hanoco, M.; Lejeune, F.J. Comparison of two cytotoxicity assays - tetrazolium derivate reduction (MTT) and tritiated thymidine uptake - on three malignant mouse cell lines using chemotherapeutic agents and investigational drugs. Anticancer Res. 1990, 10 (1), 145-154.
15. Schaaf, A.; Sagi, S.; Langbein, S.; Trojan, L.; Alken, P.; Michel, M.S. Cytotoxicity of cisplatin in bladder cancer is significantly enhanced by application of bcl-2 antisense oligonucleotides. Urol. Oncol. 2004, 22 (3), 188-192.
16. Chu, G. Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair. J. Biol. Chem. 1994, 269 (2), 787-790.
17. Safirstein, R.; Winston, J.; Goldstein, M.; Moel, D.; Dikman, S.; Guttenplan, J. Cisplatin nephrotoxicity. Am. J. Kidney Dis. 1986, 8 (5), 356-367.
18. Safirstein, R.; Winston, J.; Moel, D.; Dikman, S.; Guttenplan, J. Cisplatin nephrotoxicity: Insights into mechanism. Int. J. Androl. 1987, 10 (1), 325-346.
19. Suntres, Z.E. Role of antioxidants in paraquat toxicity. Toxicology 2002, 180 (1), 65-77.
20. Thadhani, R.; Pascual, M.; Bonventre, J.V. Acute renal failure. N. Engl. J. Med. 1996, 334 (22), 1448-1460.
21. Chan, B.S.; Lazzaro, V.A.; Seale, J.P.; Duggin, G.G. The renal excretory mechanisms and the role of organic cations in modulating the renal handling of paraquat. Pharmacol. Ther. 1998, 79 (3), 193-203.
22. Santos, B.C.; Chevaile, A.; Hebert, M.J.; Zagajeski, J.; Gullans, S.R. A combination of NaCl and urea enhances survival of IMCD cells to hyperosmolality. Am. J. Physiol. 1998, 274 (6), F1167-F1173.
23. Michea, L.; Ferguson, D.R.; Peters, E.M.; Andrews, P.M.; Kirby, M.R.; Burg, M.B. Cell cycle delay and apoptosis are induced by high salt and urea in renal medullary cells. Am. J. Physiol. Renal Physiol. 2000, 278 (2), F209-F218.