Potency of novel oximes to reactivate sarin inhibited human cholinesterases

Drug and Chemical Toxicology

Volumn 31, Issue 1, 2008, Pages 1-9

  Jun, Daniel ^a,b   Kuca, Kamil ^a,b   Picha, Jan ^c   Koleckar, Vit ^a   Marek, Jan ^d  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b UNIVERSITY OF DEFENCE   (Czech Republic)

^c INSTITUTE OF CHEMICAL TECHNOLOGY   (Czech Republic)

^d Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

Antidote; Cholinesterase; Nerve Agent; Reactivation; Sarin

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 4 PYRIDINEALDOXIME METHOSULFATE; CHOLINESTERASE REACTIVATOR; K 119; K 120; K 121; K 122; K 123; K 124; K 125; K 126; OBIDOXIME; OXIME; PRALIDOXIME; PYRIDINIUM DERIVATIVE; SARIN; UNCLASSIFIED DRUG;

ARTICLE; BRAIN HOMOGENATE; CHOLINESTERASE INHIBITION; DRUG POTENCY; HUMAN; HUMAN TISSUE; IN VITRO STUDY;

ACETYLCHOLINESTERASE; ANTIDOTES; BRAIN; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; HUMANS; MOLECULAR STRUCTURE; OBIDOXIME CHLORIDE; OXIMES; PRALIDOXIME COMPOUNDS; PYRIDINIUM COMPOUNDS; SARIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 37649006683     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.1080/01480540701688238     Document Type: Article

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