-
1
-
-
0025978216
-
A phase I clinical, plasma, and cellular pharmacology study of gemcitabine
-
Abbruzzese JL, Grunewald R, Weeks EA, et al: A phase I clinical, plasma, and cellular pharmacology study of gemcitabine. J Clin Oncol 9:491-498, 1991
-
(1991)
J Clin Oncol
, vol.9
, pp. 491-498
-
-
Abbruzzese, J.L.1
Grunewald, R.2
Weeks, E.A.3
-
2
-
-
0029963324
-
Phase I dose-escalation trial of gemcitabine and cisplatin for advanced non-small-cell lung cancer: Usefulness of mathematic modeling to determine maximum-tolerable dose
-
Shepherd FA, Burkes R, Cormier Y, et al: Phase I dose-escalation trial of gemcitabine and cisplatin for advanced non-small-cell lung cancer: Usefulness of mathematic modeling to determine maximum-tolerable dose. J Clin Oncol 14:1656-1662, 1996
-
(1996)
J Clin Oncol
, vol.14
, pp. 1656-1662
-
-
Shepherd, F.A.1
Burkes, R.2
Cormier, Y.3
-
3
-
-
0029809541
-
Gemcitabine: Preclinical pharmacology and mechanisms of action
-
5 suppl 10
-
Plunkett W, Huang P, Searcy CE, et al: Gemcitabine: Preclinical pharmacology and mechanisms of action. Semin Oncol 23:3-15, 1996 (5 suppl 10)
-
(1996)
Semin Oncol
, vol.23
, pp. 3-15
-
-
Plunkett, W.1
Huang, P.2
Searcy, C.E.3
-
4
-
-
0026550270
-
Gemcitabine in leukemia: A phase I clinical, plasma, and cellular pharmacology study
-
Grunewald R, Kantarjian H, Du M, et al: Gemcitabine in leukemia: A phase I clinical, plasma, and cellular pharmacology study. J Clin Oncol 10:406-413, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 406-413
-
-
Grunewald, R.1
Kantarjian, H.2
Du, M.3
-
5
-
-
0038578348
-
Gemcitabine pharmacokinetics and interaction with paclitaxel in patients with advanced non-small-cell lung cancer
-
Shord SS, Faucette SR, Gillenwater HH, et al: Gemcitabine pharmacokinetics and interaction with paclitaxel in patients with advanced non-small-cell lung cancer. Cancer Chemother Pharmacol 51:328-336, 2003
-
(2003)
Cancer Chemother Pharmacol
, vol.51
, pp. 328-336
-
-
Shord, S.S.1
Faucette, S.R.2
Gillenwater, H.H.3
-
6
-
-
0142121290
-
Randomized phase II comparison of doseintense gemcitabine: Thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma
-
Tempero M, Plunkett W, Ruiz Van Haperen V, et al: Randomized phase II comparison of doseintense gemcitabine: Thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma. J Clin Oncol 21:3402-3408, 2003
-
(2003)
J Clin Oncol
, vol.21
, pp. 3402-3408
-
-
Tempero, M.1
Plunkett, W.2
Ruiz Van Haperen, V.3
-
7
-
-
84871471913
-
-
Poplin E, Levy DE, Berlin J, et al: Phase III trial of gemcitabine (30-minute infusion) versus gemcitabine (fixed-dose-rate infusion [FDR]) versus gemcitabine + oxaliplatin (GEMOX) in patients with advanced pancreatic cancer (E6201). J Clin Oncol 24:LBA4004, 2006
-
Poplin E, Levy DE, Berlin J, et al: Phase III trial of gemcitabine (30-minute infusion) versus gemcitabine (fixed-dose-rate infusion [FDR]) versus gemcitabine + oxaliplatin (GEMOX) in patients with advanced pancreatic cancer (E6201). J Clin Oncol 24:LBA4004, 2006
-
-
-
-
8
-
-
0028962811
-
Validated assays for the determination of gemcitabine in human plasma and urine using highperformance liquid chromatography with ultraviolet detection
-
Freeman KB, Anliker S, Hamilton M, et al: Validated assays for the determination of gemcitabine in human plasma and urine using highperformance liquid chromatography with ultraviolet detection. J Chromatogr B Biomed Appl 665:171-181, 1995
-
(1995)
J Chromatogr B Biomed Appl
, vol.665
, pp. 171-181
-
-
Freeman, K.B.1
Anliker, S.2
Hamilton, M.3
-
9
-
-
33747780795
-
A randomized phase II trial evaluating standard (50 mg/min) versus low (10 mg/min) infusion duration of gemcitabine as first-line treatment in advanced non-small-cell lung cancer patients who are not eligible for platinum-based chemotherapy
-
Cappuzzo F, Novello S, De Marinis F, et al: A randomized phase II trial evaluating standard (50 mg/min) versus low (10 mg/min) infusion duration of gemcitabine as first-line treatment in advanced non-small-cell lung cancer patients who are not eligible for platinum-based chemotherapy. Lung Cancer 52:319-325, 2006
-
(2006)
Lung Cancer
, vol.52
, pp. 319-325
-
-
Cappuzzo, F.1
Novello, S.2
De Marinis, F.3
-
10
-
-
0038007345
-
Prolonged gemcitabine infusion in advanced non-small cell lung carcinoma: A randomized phase II study of two different schedules in combination with cisplatin
-
Ceribelli A, Gridelli C, De Marinis F, et al: Prolonged gemcitabine infusion in advanced non-small cell lung carcinoma: A randomized phase II study of two different schedules in combination with cisplatin. Cancer 98:337-343, 2003
-
(2003)
Cancer
, vol.98
, pp. 337-343
-
-
Ceribelli, A.1
Gridelli, C.2
De Marinis, F.3
-
11
-
-
33745601697
-
A multicentre randomised phase II study of carboplatin in combination with gemcitabine at standard rate or fixed dose rate infusion in patients with advanced stage non-small-cell lung cancer
-
Soo RA, Wang LZ, Tham LS, et al: A multicentre randomised phase II study of carboplatin in combination with gemcitabine at standard rate or fixed dose rate infusion in patients with advanced stage non-small-cell lung cancer. Ann Oncol 17:1128-1133, 2006
-
(2006)
Ann Oncol
, vol.17
, pp. 1128-1133
-
-
Soo, R.A.1
Wang, L.Z.2
Tham, L.S.3
-
12
-
-
84871467405
-
Gemcitabine (G) plasma and intracellular pharmacokinetics in E6201: Greater metabolite levels using fixed dosing rate (FDR) delivery
-
Liebes L, Levy DE, Poplin E, et al: Gemcitabine (G) plasma and intracellular pharmacokinetics in E6201: Greater metabolite levels using fixed dosing rate (FDR) delivery. J Clin Oncol 24:2024, 2006
-
(2006)
J Clin Oncol
, vol.24
, pp. 2024
-
-
Liebes, L.1
Levy, D.E.2
Poplin, E.3
-
13
-
-
0035863027
-
Activation of deoxycytidine kinase by inhibition of DNA synthesis in human lymphocytes
-
Csapo Z, Sasvari-Szekely M, Spasokoukotskaja T, et al: Activation of deoxycytidine kinase by inhibition of DNA synthesis in human lymphocytes. Biochem Pharmacol 61:191-197, 2001
-
(2001)
Biochem Pharmacol
, vol.61
, pp. 191-197
-
-
Csapo, Z.1
Sasvari-Szekely, M.2
Spasokoukotskaja, T.3
-
14
-
-
0025978611
-
Induction of deoxycytidine kinase by 5-azacytidine in an HL-60 cell line resistant to arabinosylcytosine
-
Kong XB, Tong WP, Chou TC: Induction of deoxycytidine kinase by 5-azacytidine in an HL-60 cell line resistant to arabinosylcytosine. Mol Pharmacol 39:250-257, 1991
-
(1991)
Mol Pharmacol
, vol.39
, pp. 250-257
-
-
Kong, X.B.1
Tong, W.P.2
Chou, T.C.3
-
15
-
-
0002831066
-
Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity
-
Kroep JR, Loves WJ, van der Wilt CL, et al: Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity. Mol Cancer Ther 1:371-376, 2002
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 371-376
-
-
Kroep, J.R.1
Loves, W.J.2
van der Wilt, C.L.3
-
16
-
-
12144285914
-
Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients
-
Rosell R, Danenberg KD, Alberola V, et al: Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Clin Cancer Res 10:1318-1325, 2004
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1318-1325
-
-
Rosell, R.1
Danenberg, K.D.2
Alberola, V.3
-
17
-
-
19944429421
-
Ribonucleotide reductase M1 gene promoter activity, polymorphisms, population frequencies, and clinical relevance
-
Bepler G, Zheng Z, Gautam A, et al: Ribonucleotide reductase M1 gene promoter activity, polymorphisms, population frequencies, and clinical relevance. Lung Cancer 47:183-192, 2005
-
(2005)
Lung Cancer
, vol.47
, pp. 183-192
-
-
Bepler, G.1
Zheng, Z.2
Gautam, A.3
-
18
-
-
9244234326
-
Association between single nucleotide polymorphisms in deoxycytidine kinase and treatment response among acute myeloid leukaemia patients
-
Shi JY, Shi ZZ, Zhang SJ, et al: Association between single nucleotide polymorphisms in deoxycytidine kinase and treatment response among acute myeloid leukaemia patients. Pharmacogenetics 14:759-768, 2004
-
(2004)
Pharmacogenetics
, vol.14
, pp. 759-768
-
-
Shi, J.Y.1
Shi, Z.Z.2
Zhang, S.J.3
-
19
-
-
0037245970
-
A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity
-
Yue L, Saikawa Y, Ota K, et al: A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity. Pharmacogenetics 13:29-38, 2003
-
(2003)
Pharmacogenetics
, vol.13
, pp. 29-38
-
-
Yue, L.1
Saikawa, Y.2
Ota, K.3
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