Effects of Panax notoginseng saponins on long-term potentiation in the CA1 region of the rat hippocampus

Yaoxue Xuebao

Volumn 42, Issue 11, 2007, Pages 1137-1141

  Zhou, Yan ^a   Song, Hui ^a   Ning, Zong ^b   Tian, Lei ^b   Xu, Lin ^c   Mo, Ning ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

^c KUNMING INSTITUTE OF ZOOLOGY   (China)

Author keywords

Excitatory postsynaptic current; Hippocampus; Long term potentiation; Panax notoginseng; Synaptic plasticity

Indexed keywords

GINSENOSIDE;

ANIMAL; ARTICLE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; ISOLATION AND PURIFICATION; LONG TERM POTENTIATION; NERVE CELL; PANAX NOTOGINSENG; PHYSIOLOGY; PYRAMIDAL NERVE CELL; RAT; WISTAR RAT;

ANIMALS; EXCITATORY POSTSYNAPTIC POTENTIALS; GINSENOSIDES; HIPPOCAMPUS; LONG-TERM POTENTIATION; NEURONS; PANAX NOTOGINSENG; PYRAMIDAL CELLS; RATS; RATS, WISTAR;

EID: 37549067012     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Ma LY, Xiao PG. Effects of PNS on synaptosomal glutamate release and on its specific binding to glutamatic receptor [J]. Chin Pharmacol Bull, 1998,14:311-314.
2. Wu LO, Wu P, Lu J, et al. Study of Sanchi Saponin Rg1 on chemical memory-disturbance [J]. Yunnan J Tradit Chin Med Mater Med, 2002,23: 36-38.
3. Qao P, Yang GZ. Study of learning and memory function in D-galactose model mice improved by Sanchi Saponin Rg1 and its participating factors [J]. Chin J Immunol, 2003,19:772-774.
4. Guo CJ, Wu JX, Li RX. The effects of PNS on Alzheimer's disease model of mouse and mechanism of the effects [J]. J China Pharm, 2004,15: 598-600.
5. Wang XY, Chen J, Zhang JT. Effects of ginsenoside Rg1 on learning and memory impairment induced by β-amyloid peptide (25-35) and its mechanism of action [J]. Acta Pharm Sin, 2001,36:1-4.
6. Nalbantoglu J, Tirado-Santiago G, Lahsaini A, et al. Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein [J]. Nature, 1997,387:500-505.
7. Rao Y, Lai SL, Hu JQ, et al. Effects of BuShenYiZhi Prescription on long-term potentiation of aged rat with senile dementia [J]. J Guangzhou Univ Tradit Chin Med, 2000,17:109-112.
8. Sun XH, Zhang JC, Li HB, et al. Propofol effects on excitatory synaptic efficacy in the CA1 region of the developing hippocampus [J]. Dev Brain Res, 2005, 157:1-7.
9. Wang JH, Ko GY, Kelly PT. Cellular and molecular hases of memory: synaptic and neuronal plasticity [J]. J Clin Neurophysiol, 1997,14:264-293.
10. Morris RG. Elements of a neurobiologieal theory of hippocampal function: the role of synaptic plasticity, synaptic tagging and schemas [J]. Eur J Neurosci, 2006,23:2829-2846.
11. Mei ZT. Learning and memory [M]//Han JS. Principle in Neuroscience. 2nd ed. Beijing: Peking Union Medical College and Beijing Medical University Press, 1999:916-935.
12. Bliss TV, Collingridge GL. A synaptic model of memory: long-term potentiation in the hippocampus [J]. Nature, 1993,361:31-39.
13. Malenka RC, Nicoll RA. Long-term potentiation - a decade of progress? [J]. Science, 1999,285:1870-1874.
14. Martin SJ, Grimwood PD, Morris RG. Synaptic plasticity and memory: an evaluation of the hypothesis [J]. Annu Rev Neurosci, 2000,23:649-711.
15. Xu SF. Neurobiology [M]. 2nd ed. Shanghai: Shanghai Medical University Press, 1999: 389-397.
16. Zhang JT. Diference of biological activities between Rg1 and Rb1 [J]. Basic Med Sci Clin, 2000,20:4-6.
17. Zhang JT. Nootropic mechanisms of ginsenoside Rg1 influence on neuronal plasticity and neurogenesis [J]. Acta Pharm Sin, 2005,40:385-388.