Chemical modulators of heat shock protein 70 (Hsp70) by sequential, microwave-accelerated reactions on solid phase

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 1, 2008, Pages 60-65

  Wisén, Susanne ^a   Androsavich, John ^a   Evans, Christopher G ^a   Chang, Lyra ^a   Gestwicki, Jason E ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Peptide; Biginelli; Cancer; Chaperone; Dihydropyrimidine; Neurodegenerative disease

Indexed keywords

15 DEOXYSPERGUALIN; ADENOSINE TRIPHOSPHATASE; CHAPERONE; GELDANAMYCIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; MAL 3 101; MAL 3 90; N TETRADECANOYL (4 AMINOMETHYLBENZOYL)ISOLEUCINE; NSC 630668; PROTEIN DNAK; PYRIMIDINE DERIVATIVE; SW 02; TANESPIMYCIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIGINELLI REACTION; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; MICROWAVE IRRADIATION; SOLID PHASE SYNTHESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACIDS; ANIMALS; FLUORENES; HSP70 HEAT-SHOCK PROTEINS; MICROWAVES; OLIGOPEPTIDES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS);

EID: 37549046818     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.11.027     Document Type: Article

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