EWSR1-CREB1 and EWSR1-ATF1 fusion genes in angiomatoid fibrous histiocytoma

Clinical Cancer Research

Volumn 13, Issue 24, 2007, Pages 7322-7328

  Rossi, Sabrina ^a   Szuhai, Kàroly ^b   Ijszenga, Marije ^b   Tanke, Hans J ^b   Zanatta, Lucia ^a   Sciot, Raf ^c   Fletcher, Christopher D M ^d   DeiTos, Angelo P ^a   Hogendoorn, Pancras C W ^b  

^a Regional Hospital   (Italy)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ANGIOMATOID FIBROUS HISTIOCYTOMA; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DERMATOFIBROMA; EWSR1 ATF1 GENE; EWSR1 CREB1 GENE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FUSION GENE; GENE REARRANGEMENT; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; MALE; MOLECULAR PROBE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE SECTION;

ADOLESCENT; ADULT; BASE SEQUENCE; CHILD; CHILD, PRESCHOOL; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FEMALE; HISTIOCYTOMA, MALIGNANT FIBROUS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; ONCOGENE PROTEINS, FUSION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SOFT TISSUE NEOPLASMS; TRANSCRIPTION FACTORS;

EID: 37549038654     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-07-1744     Document Type: Article

References (26)

1. Fanburg-Smith JC, Dal Cin P. Angiomatoid fibrous histiocytoma. Fletcher CDM, Unni KK, Mertens F. WHO classification of tumours. Pathology and genetics of tumours of soft tissue and bone. 194-5. IARC Press. Lyon, 2002.
2. Fletcher CD. Angiomatoid "malignant fibrous histiocytoma": an immunohistochemical study indicative of myoid differentiation. Hum Pathol 1991;22:563-68.
3. Fanburg-Smith JC, Miettinen M. Angiomatoid "malignant" fibrous histiocytoma: a clinicopathologic study of 158 cases and further exploration of the myoid phenotype. Hum Pathol 1999;30:1336-43.
4. Waters BL, Panagopoulos I, and Allen EF. Genetic characterization of angiomatoid fibrous histiocytoma identifies fusion of the FUS and ATF-1 genes induced by a chromosomal translocation involving bands 12q13 and 16p11. Cancer Genet Cytogenet 2000;121:109-16.
5. Hallor KH, Mertens F, Jin Y, Meis-Kindblom JM, Kindblom LG, Behrendtz M, et al. Fusion of the EWSR1 and ATF1 genes without expression of the MITF-M transcript in angiomatoid fibrous histiocytoma. Genes Chromosomes Cancer 2005;44:97-102.
6. Raddaoui E, Donner LR, Panagopoulos I. Fusion of the FUS and ATF1 genes in a large, deep-seated angiomatoid fibrous histiocytoma. Diagn Mol Pathol 2002;11:157-62.
7. Hallor KH, Micci F, Meis-Kindblom JM, et al. Fusion genes in angiomatoid fibrous histiocytoma. Cancer Lett 2007;25:158-63.
8. Law WJ, Cann KL, Hicks GG. TLS, EWS, and TAF15: a model for transcriptional integration of gene expression. Brief Funct Genomic Proteomic 2006;5:8-14.
9. Persengiev SP, Green MR. The role of ATF/CREB family members in cell growth, survival and apoptosis. Apoptosis 2003;8:225-8.
10. Shing DC, McMullan DJ, Roberts P, et al. FUS/ERG gene fusions in Ewing's tumors. Cancer Res 2003;63:4568-76.
11. Kaneko Y, Kobayashi H, Handa M, Satake N, Maseki N. EWS-ERG fusion transcript produced by chromosomal insertion in a Ewing sarcoma. Genes Chromosomes Cancer 1997;18:228-31.
12. Crozat A, Aman P, Mandahl N, Ron D. Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma. Nature 1993;363:640-4.
13. Panagopoulos I, Höglund M, Mertens F, Mandahl N, Mitelman F, Aman P. Fusion of the EWS and CHOP genes in myxoid liposarcoma. Oncogene 1996;12:489-94.
14. Panagopoulos I, Mertens F, Debiec-Rychter M, et al. Molecular genetic characterization of the EWS/ATF1 fusion gene in clear cell sarcoma of tendons and aponeuroses. Int J Cancer 2002;99:560-7.
15. Antonescu CR, Tschernyavsky SJ, Woodruff JM, Jungbluth AA, Brennan MF, Ladanyi M. Molecular diagnosis of clear cell sarcoma: detection of EWS-ATF1 and MITF-M transcripts and histopathological and ultrastructural analysis of 12 cases. J Mol Diagn 2002;4:44-52.
16. Antonescu CR, Nafa K, Segal NH, Dal Cin P, Ladanyi M. EWS-CREB1: a recurrent variant fusion in clear cell sarcoma-association with gastrointestinal location and absence of melanocytic differentiation. Clin Cancer Res 2006;12:5356-62.
17. Terra SBSP, Folpe AL, Weiss SW, et al. Frequency and characterization of ATF1 - fusion genes in angiomatoid fibrous histiocytoma [abstract 76]. Mod Pathol 2007;20.
18. Antonescu CR, Dal Cin P, Nafa K, Teot LA, Fletcher CDM, Ladanyi M. EWS-CREB1 is the predominant gene fusion in so-called angiomatoid fibrous histiocytoma [abstract 31]. Mod Pathol 2007;20.
19. Antonescu CR, Dal Cin P, Nafa K, et al. EWSR1-1 is the predominant gene fusion in angiomatoid fibrous histiocytoma. Genes Chromosomes Cancer 2007;46:1051-60.
20. Baelde HJ, Cleton-Jansen AM, van Beerendonk H, Namba M, Bovee JV, Hogendoorn PC. High quality RNA isolation from tumours with low cellularity and high extracellular matrix component for cDNA microarrays: application to chondrosarcoma. J Clin Pathol 2001;54:778-82.
21. Helman LJ, Meltzer P. Mechanisms of sarcoma development. Nat Rev Cancer 2003;3:685-94.
22. Stenman G. Fusion oncogenes and tumor type specificity - insights from salivary gland tumors. Semin Cancer Biol 2005;15:224-35.
23. Lannon CL, Sorensen PH. ETV6-3: a chimeric protein tyrosine kinase with transformation activity in multiple cell lineages. Semin Cancer Biol 2005;15:215-23.
24. Greaves MF, Maia AT, Wiemels JL, Ford AM. Leukemia in twins: lessons in natural history. Blood 2003;102:2321-33.
25. Davis IJ, Kim JJ, Ozsolak F, et al. Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers. Cancer Cell 2006;9:473-84.
26. Li KK, Goodall J, Goding CR, et al. The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma. Br J Cancer 2003;89:1072-8.