Anterograde transsynaptic tracing in the murine somatosensory system using Pseudorabies virus (PrV): A "live-cell"-tracing tool for analysis of identified neurons in vitro

Journal of NeuroVirology

Volumn 13, Issue 6, 2007, Pages 579-585

  Rothermel, Markus ^a   Schöbel, Nicole ^a   Damann, Nils ^a   Klupp, Barbara G ^b   Mettenleiter, Thomas C ^b   Hatt, Hanns ^a   Wetzel, Christian H ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

Mice; Nasal mucosa; Patch clamp; Pseudorabies virus; Trigeminal system

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CELL FUNCTION; CELL LABELING; CONTROLLED STUDY; DISEASE COURSE; FUNCTIONAL ASSESSMENT; HERPES VIRUS INFECTION; IN VITRO STUDY; MOUSE; NERVE CELL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NONHUMAN; PRIORITY JOURNAL; PSEUDORABIES HERPETOVIRUS; SOMATOSENSORY SYSTEM; SYNAPSE; VIRUS CELL INTERACTION; VIRUS STRAIN; VIRUS VIRULENCE;

ANIMALS; CENTRAL NERVOUS SYSTEM; HERPESVIRUS 1, SUID; MICE; NEURONS; PSEUDORABIES; SYNAPSES; SYNAPTIC TRANSMISSION;

MAMMALIA; MURINAE; MUS; SUID HERPESVIRUS 1;

EID: 37549038190     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.1080/13550280701586419     Document Type: Article

References (25)

1. Billig, I., Foris, J. M., Enquist, L. W., Card, J. P. and Yates, B. J. (2000) Definition of neuronal circuitry controlling the activity of phrenic and abdominal motoneurons in the ferret using recombinant strains of pseudorabies virus. J Neurosci, 20, pp. 7446-7454.
2. Cano, G., Sved, A. F., Rinaman, L., Rabin, B. S. and Card, J. P. (2001) Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing. J Comp Neurol, 439, pp. 1-18.
3. Damann, N., Rothermel, M., Klupp, B. G., Mettenleiter, T. C., Hatt, H. and Wetzel, C. H. (2006) Chemosensory properties of murine nasal and cutaneous trigeminal neurons identified by viral tracing. BMC Neurosci, 7, p. 46.
4. Damann, N., Klopfleisch, R., Rothermel, M., Doerner, J. F., Mettenleiter, T. C., Hatt, H. and Wetzel, C. H. (2006) Neuronal pathways of viral invasion in mice after intranasal inoculation of pseudorabies virus PrV-9112C2 expressing bovine herpesvirus 1 glycoprotein B. J Neurovirol, 12, pp. 60-64.
5. Darian-Smith, I., Johnson, K. O. and Dykes, R. (1973) "Cold" fiber population innervating palmar and digital skin of the monkey: responses to cooling pulses. J Neurophysiol, 36, pp. 325-346.
6. DeFalco, J., Tomishima, M., Liu, H., Zhao, C., Cai, X., Marth, J. D., Enquist, L. and Friedman, J. M. (2001) Virus-assisted mapping of neural inputs to a feeding center in the hypothalamus. Science, 291, pp. 2608-2613.
7. Enquist, L. W. (1994) Infection of the mammalian nervous system by pseudorabies virus (PrV). Semin Virol, 5, pp. 221-231.
8. Enquist, L. W. (2002) Exploiting circuit-specific spread of pseudorabies virus in the central nervous system: Insights to pathogenesis and circuit tracers. J Infect Dis, 186, pp. S209-S214.
9. Horvath, M., Ribari, O., Repassy, G., Toth, I. E., Boldogkoi, Z. and Palkovits, M. (2003) Intracochlear injection of pseudorabies virus labels descending auditory and monoaminerg projections to olivocochlear cells in guinea pig. Eur J Neurosci, 18, pp. 1439-1447.
10. Irnaten, M., Neff, R. A., Wang, J., Loewy, A. D., Mettenleiter, T. C. and Mendelowitz, D. (2001) Activity of cardiorespiratory networks revealed by transsynaptic virus expressing GFP. J Neurophysiol, 85, pp. 435-438.
11. Jansen, A. S., Hoffman, J. L. and Loewy, A. D. (1997) CNS sites involved in sympathetic and parasympathetic control of the pancreas: A viral tracing study. Brain Res, 766, pp. 29-38.
12. Jansen, A. S., Nguyen, X. V., Karpitskiy, V., Mettenleiter, T. C. and Loewy, A. D. (1995) Central command neurons of the sympathetic nervous system: Basis of the fight-or-flight response. Science, 270, pp. 644-646.
13. Jansen, A. S., Hoffman, J. L. and Loewy, A. D. (1997) CNS sites involved in sympathetic and parasympathetic control of the pancreas: A viral tracing study. Brain Res, 766, pp. 29-38.
14. Jasmin, L., Burkey, A. R., Card, J. P. and Basbaum, A. I. (1997) Transneuronal labeling of a nociceptive pathway, the spino-(trigemino-)parabrachio-amygdaloid, in the rat. J Neurosci, 17, pp. 3751-3765.
15. Krout, K. E., Mettenleiter, T. C. and Loewy, A. D. (2003) Single CNS neurons link both central motor and cardiosympathetic systems: A double-virus tracing study. Neuroscience, 118, pp. 853-866.
16. Lo, F. S., Guido, W. and Erzurumlu, R. S. (1999) Electrophysiological properties and synaptic responses of cells in the trigeminal principal sensory nucleus of postnatal rats. J Neurophysiol, 82, pp. 2765-2775.
17. Mayer, M. L., James, M. H., Russell, R. J., Kelly, J. S. and Pasternak, C. A. (1986) Changes in excitability induced by herpes simplex viruses in rat dorsal root ganglion neurons. J Neurosci, 6, pp. 391-402.
18. Mettenleiter, T. C. (1994) Pseudorabies (Aujeszky's disease) virus: state of the art. August 1993. Acta Vet Hung, 42, pp. 153-177.
19. Patapoutian, A., Peier, A. M., Story, G. M. and Viswanath, V. (2003) ThermoTRP channels and beyond: Mechanisms of temperature sensation. Nat Rev Neurosci, 4, pp. 529-539.
20. Pensaert, M. and Kluge, J. (1989) Pseudorabies virus (Aujeszky's disease), pp. 39-64. Elsevier Science, St. Louis
21. Sabin, A. B. (1938) Progression of different nasally instilled viruses along different nervous pathways in the same host. Proc Soc Exp Biol Med, 38, pp. 270-275.
22. Smith, B. N., Banfield, B. W., Smeraski, C. A., Wilcox, C. L., Dudek, F. E., Enquist, L. W. and Pickard, G. E. (2000) Pseudorabies virus expressing enhanced green fluorescent protein: A tool for in vitro electrophysiological analysis of transsynaptically labeled neurons in identified central nervous system circuits. Proc Natl Acad Sci U S A, 97, pp. 9264-9269.
23. Song, C. K., Enquist, L. W. and Bartness, T. J. (2005) New developments in tracing neural circuits with herpesviruses. Virus Res, 111, pp. 235-249.
24. Storey, N., Latchman, D. and Bevan, S. (2002) Selective internalization of sodium channels in rat dorsal root ganglion neurons infected with herpes simplex virus-1. J Cell Biol, 158, pp. 1251-1262.
25. van, D En, Top, M., Nolan, M. F., Lee, K., Richardson, P. J., Buijs, R. M., Davies, C. H. and Spanswick, D. (2003) Orexins induce increased excitability and synchronisation of rat sympathetic preganglionic neurones. J Physiol, 549, pp. 809-821.