-
3
-
-
1442355642
-
Primer on medical genomics. Part XII: Pharmacogenomics-general principles with cancer as a model
-
Goetz MP, Ames MM and Weinshilboum RM: Primer on medical genomics. Part XII: Pharmacogenomics-general principles with cancer as a model. Mayo Clin Proc 79: 376-384, 2004.
-
(2004)
Mayo Clin Proc
, vol.79
, pp. 376-384
-
-
Goetz, M.P.1
Ames, M.M.2
Weinshilboum, R.M.3
-
5
-
-
0032143631
-
Characterization of the human dihydropyrimidine dehydrogenase gene
-
Wei X, Elizondo G, Sapone A, McLeod HL, Raunio H, Fernandez-Salguero P and Gonzalez FJ: Characterization of the human dihydropyrimidine dehydrogenase gene. Genomics 51: 391-400, 1998.
-
(1998)
Genomics
, vol.51
, pp. 391-400
-
-
Wei, X.1
Elizondo, G.2
Sapone, A.3
McLeod, H.L.4
Raunio, H.5
Fernandez-Salguero, P.6
Gonzalez, F.J.7
-
6
-
-
0032974922
-
Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency
-
van Kuilenburg AB, Vreken P, Abeling NG, Bakker HD, Meinsma R, Van Lenthe H, De Abreu RA, Smeitink JA, Kayserili H, Apak MY, Christensen E, Holopainen I, Pulkki K, Riva D, Botteon G, Holme E, Tulinius M, Kleijer WJ, Beemer FA, Duran M, Niezen-Koning KE, Smit GP, Jakobs C, Smit LM, van Gennip AH et al: Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency. Hum Genet 104: 1-9, 1999.
-
(1999)
Hum Genet
, vol.104
, pp. 1-9
-
-
van Kuilenburg, A.B.1
Vreken, P.2
Abeling, N.G.3
Bakker, H.D.4
Meinsma, R.5
Van Lenthe, H.6
De Abreu, R.A.7
Smeitink, J.A.8
Kayserili, H.9
Apak, M.Y.10
Christensen, E.11
Holopainen, I.12
Pulkki, K.13
Riva, D.14
Botteon, G.15
Holme, E.16
Tulinius, M.17
Kleijer, W.J.18
Beemer, F.A.19
Duran, M.20
Niezen-Koning, K.E.21
Smit, G.P.22
Jakobs, C.23
Smit, L.M.24
van Gennip, A.H.25
more..
-
7
-
-
0032408978
-
Nomenclature for human DPYD alleles
-
McLeod HL, Collie-Duguid ES, Vreken P, Johnson MR, Wei X, Sapone A, Diasio RB, Fernandez-Salguero P, van Kuilenberg AB, van Gennip AH and Gonzalez FJ: Nomenclature for human DPYD alleles. Pharmacogenetics 8: 455-459, 1998.
-
(1998)
Pharmacogenetics
, vol.8
, pp. 455-459
-
-
McLeod, H.L.1
Collie-Duguid, E.S.2
Vreken, P.3
Johnson, M.R.4
Wei, X.5
Sapone, A.6
Diasio, R.B.7
Fernandez-Salguero, P.8
van Kuilenberg, A.B.9
van Gennip, A.H.10
Gonzalez, F.J.11
-
8
-
-
7344249042
-
Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects
-
Ridge SA, Sludden J, Brown O, Robertson L, Wei X, Sapone A, Fernandez-Salguero PM, Gonzalez FJ, Vreken P, van Kuilenburg AB, van Gennip AH and McLeod HL: Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects. Br J Clin Pharmacol 46: 151-156, 1998.
-
(1998)
Br J Clin Pharmacol
, vol.46
, pp. 151-156
-
-
Ridge, S.A.1
Sludden, J.2
Brown, O.3
Robertson, L.4
Wei, X.5
Sapone, A.6
Fernandez-Salguero, P.M.7
Gonzalez, F.J.8
Vreken, P.9
van Kuilenburg, A.B.10
van Gennip, A.H.11
McLeod, H.L.12
-
9
-
-
0028813120
-
Human polymorphism in drug metabolism: Mutation in the dihydropyrimidine dehydrogenase gene results in exon skipping and thymine uracilurea
-
Meinsma R, Fernandez-Salguero P, van Kuilenburg AB, van Gennip AH and Gonzalez FJ: Human polymorphism in drug metabolism: mutation in the dihydropyrimidine dehydrogenase gene results in exon skipping and thymine uracilurea. DNA Cell Biol 14: 1-6, 1995.
-
(1995)
DNA Cell Biol
, vol.14
, pp. 1-6
-
-
Meinsma, R.1
Fernandez-Salguero, P.2
van Kuilenburg, A.B.3
van Gennip, A.H.4
Gonzalez, F.J.5
-
10
-
-
1942453306
-
Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil
-
van Kuilenburg AB: Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil. Eur J Cancer 40: 939-950, 2004.
-
(2004)
Eur J Cancer
, vol.40
, pp. 939-950
-
-
van Kuilenburg, A.B.1
-
11
-
-
0036252486
-
Dihydropyrimidine dehydrogenase enzyme deficiency: Clinical and genetic assessment of prevalence in Turkish cancer patients
-
Celik I, Kars A, Guc D, Tekuzman G and Ruacan S: Dihydropyrimidine dehydrogenase enzyme deficiency: clinical and genetic assessment of prevalence in Turkish cancer patients. Cancer Invest 20: 333-339, 2002.
-
(2002)
Cancer Invest
, vol.20
, pp. 333-339
-
-
Celik, I.1
Kars, A.2
Guc, D.3
Tekuzman, G.4
Ruacan, S.5
-
12
-
-
33845686211
-
Prospective study of dihydropyrimidine dehydrogenase (DPD) activity and DPYD IVS14+1G > A mutation in patients developing FU-related toxicities: An updated analysis based on a ten-year recruitment across multiple French institutions
-
Magne N, Renee N, Formento JL, Etienne-Grimaldi MC, Francoual M and Milano G: Prospective study of dihydropyrimidine dehydrogenase (DPD) activity and DPYD IVS14+1G > A mutation in patients developing FU-related toxicities: An updated analysis based on a ten-year recruitment across multiple French institutions. J Clin Oncol (Meeting Abstracts) 23: 16S, 2005.
-
(2005)
J Clin Oncol (Meeting Abstracts)
, vol.23
-
-
Magne, N.1
Renee, N.2
Formento, J.L.3
Etienne-Grimaldi, M.C.4
Francoual, M.5
Milano, G.6
-
13
-
-
34447321898
-
Dihydropyrimidine dehydrogenase activity and the IVS14+1G > A mutation in patients developing 5FU-related toxicity
-
Magne N, Etienne-Grimaldi MC, Cals L, Renee N, Formento JL, Francoual M and Milano G: Dihydropyrimidine dehydrogenase activity and the IVS14+1G > A mutation in patients developing 5FU-related toxicity. Br J Clin Pharmacol 64: 237-240, 2007.
-
(2007)
Br J Clin Pharmacol
, vol.64
, pp. 237-240
-
-
Magne, N.1
Etienne-Grimaldi, M.C.2
Cals, L.3
Renee, N.4
Formento, J.L.5
Francoual, M.6
Milano, G.7
-
14
-
-
0034901306
-
Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: Frequency of the common IVS14+1G > A mutation causing DPD deficiency
-
van Kuilenburg AB, Muller EW, Haasjes J, Meinsma R, Zoetekouw L, Waterham HR, Baas F, Richel DJ and van Gennip AH: Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G > A mutation causing DPD deficiency. Clin Cancer Res 7: 1149-1153, 2001.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1149-1153
-
-
van Kuilenburg, A.B.1
Muller, E.W.2
Haasjes, J.3
Meinsma, R.4
Zoetekouw, L.5
Waterham, H.R.6
Baas, F.7
Richel, D.J.8
van Gennip, A.H.9
-
15
-
-
0034808681
-
Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls
-
Raida M, Schwabe W, Hausler P, van Kuilenburg AB, van Gennip AH, Behnke D and Hoffken K: Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls. Clin Cancer Res 7: 2832-2839, 2001.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2832-2839
-
-
Raida, M.1
Schwabe, W.2
Hausler, P.3
van Kuilenburg, A.B.4
van Gennip, A.H.5
Behnke, D.6
Hoffken, K.7
-
16
-
-
11144355814
-
Mutations in exon 14 of dihydropyrimidine dehydrogenase and 5-fluorouracil toxicity in Portuguese colorectal cancer patients
-
Salgueiro N, Veiga I, Fragoso M, Sousa O, Costa N, Pellon ML, Sanches E, dos Santos JG, Teixeira MR and Castedo S: Mutations in exon 14 of dihydropyrimidine dehydrogenase and 5-fluorouracil toxicity in Portuguese colorectal cancer patients. Genet Med 6: 102-107, 2004.
-
(2004)
Genet Med
, vol.6
, pp. 102-107
-
-
Salgueiro, N.1
Veiga, I.2
Fragoso, M.3
Sousa, O.4
Costa, N.5
Pellon, M.L.6
Sanches, E.7
dos Santos, J.G.8
Teixeira, M.R.9
Castedo, S.10
-
17
-
-
29144493773
-
TYMS and DPYD polymorphisms in a Turkish population
-
Suzen HS, Yuce N, Guvenc G, Duydu Y and Erke T: TYMS and DPYD polymorphisms in a Turkish population. Eur J Clin Pharmacol 61: 881-885, 2005.
-
(2005)
Eur J Clin Pharmacol
, vol.61
, pp. 881-885
-
-
Suzen, H.S.1
Yuce, N.2
Guvenc, G.3
Duydu, Y.4
Erke, T.5
-
18
-
-
33749828072
-
A rapid and inexpensive method for anticipating severe toxicity to fluorouracil and fluorouracil-based chemotherapy
-
Ciccolini J, Mercier C, Evrard A, Dahan L, Boyer JC, Duffaud F, Richard K, Blanquicett C, Milano G, Blesius A, Durand A, Seitz JF, Favre R and Lacarelle B: A rapid and inexpensive method for anticipating severe toxicity to fluorouracil and fluorouracil-based chemotherapy. Ther Drug Monit 28: 678-685, 2006.
-
(2006)
Ther Drug Monit
, vol.28
, pp. 678-685
-
-
Ciccolini, J.1
Mercier, C.2
Evrard, A.3
Dahan, L.4
Boyer, J.C.5
Duffaud, F.6
Richard, K.7
Blanquicett, C.8
Milano, G.9
Blesius, A.10
Durand, A.11
Seitz, J.F.12
Favre, R.13
Lacarelle, B.14
-
19
-
-
34248157706
-
Thymidylate synthase (TYMS) and dihydropyrimidine dehydrogenase (DPYD) polymorphisms in the Korean population for prediction of 5-fluorouracil-associated toxicity
-
Cho HJ, Park YS, Kang WK, Kim JW and Lee SY: Thymidylate synthase (TYMS) and dihydropyrimidine dehydrogenase (DPYD) polymorphisms in the Korean population for prediction of 5-fluorouracil-associated toxicity. Ther Drug Monit 29: 190-196, 2007.
-
(2007)
Ther Drug Monit
, vol.29
, pp. 190-196
-
-
Cho, H.J.1
Park, Y.S.2
Kang, W.K.3
Kim, J.W.4
Lee, S.Y.5
-
20
-
-
2142653547
-
Dihydropyrimidine dehydrogenase pharmacogenetics in the Taiwanese population
-
Hsiao HH, Yang MY, Chang JG, Liu YC, Liu TC, Chang CS, Chen TP and Lin SF: Dihydropyrimidine dehydrogenase pharmacogenetics in the Taiwanese population. Cancer Chemother Pharmacol 53: 445-451, 2004.
-
(2004)
Cancer Chemother Pharmacol
, vol.53
, pp. 445-451
-
-
Hsiao, H.H.1
Yang, M.Y.2
Chang, J.G.3
Liu, Y.C.4
Liu, T.C.5
Chang, C.S.6
Chen, T.P.7
Lin, S.F.8
-
21
-
-
0035987174
-
Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian population
-
Hamdy SI, Hiratsuka M, Narahara K, El-Enany M, Moursi N, Ahmed MS and Mizugaki M: Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian population. Br J Clin Pharmacol 53: 596-603, 2002.
-
(2002)
Br J Clin Pharmacol
, vol.53
, pp. 596-603
-
-
Hamdy, S.I.1
Hiratsuka, M.2
Narahara, K.3
El-Enany, M.4
Moursi, N.5
Ahmed, M.S.6
Mizugaki, M.7
-
22
-
-
0141615759
-
Use of pyrosequencing to detect clinically relevant polymorphisms in dihydropyrimidine dehydrogenase
-
Ahluwalia R, Freimuth R, McLeod HL and Marsh S: Use of pyrosequencing to detect clinically relevant polymorphisms in dihydropyrimidine dehydrogenase. Clin Chem 49: 1661-1664, 2003.
-
(2003)
Clin Chem
, vol.49
, pp. 1661-1664
-
-
Ahluwalia, R.1
Freimuth, R.2
McLeod, H.L.3
Marsh, S.4
-
23
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
Miller SA, Dykes DD and Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16: 1215, 1998.
-
(1998)
Nucleic Acids Res
, vol.16
, pp. 1215
-
-
Miller, S.A.1
Dykes, D.D.2
Polesky, H.F.3
-
24
-
-
0034488052
-
Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: Identification of new mutations in the DPD gene
-
van Kuilenburg AB, Haasjes J, Richel DJ, Zoetekouw L, Van Lenthe H, De Abreu RA, Maring JG, Vreken P and van Gennip AH: Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene. Clin Cancer Res 6: 4705-4712, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4705-4712
-
-
van Kuilenburg, A.B.1
Haasjes, J.2
Richel, D.J.3
Zoetekouw, L.4
Van Lenthe, H.5
De Abreu, R.A.6
Maring, J.G.7
Vreken, P.8
van Gennip, A.H.9
|