Generation of natural killer cells from serum-free, expanded human umbilical cord blood CD34+ cells

Stem Cells and Development

Volumn 16, Issue 6, 2007, Pages 1043-1051

  Kao, I Ting ^a   Yao, Chao Ling ^a   Kong, Zwe Ling ^b   Wu, Mei Ling ^a   Chuang, Tzu Lin ^a   Hwang, Shiaw Min ^a  

^a FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE   (Taiwan)

^b NATIONAL TAIWAN OCEAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; GAMMA INTERFERON; GROWTH FACTOR; LACTATE DEHYDROGENASE; MESSENGER RNA;

ARTICLE; CELL DENSITY; CELL GROWTH; CELL STRAIN K 562; CYTOKINE RELEASE; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; UMBILICAL CORD BLOOD;

ANTIGENS, CD34; CELL DIFFERENTIATION; CELL SURVIVAL; CULTURE MEDIA; FEMALE; FETAL BLOOD; HEMATOPOIETIC STEM CELLS; HUMANS; KILLER CELLS, NATURAL; PREGNANCY; UMBILICAL CORD;

EID: 37549024529     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2007.0033     Document Type: Article

References (32)

1. Farag SS, TA Fehniger, L Ruggeri, A Velardi and MA Caligiuri. (2002). Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effect. Blood 100:1935-1947.
2. Vujanovic NL, P Basse, RB Herberman and TL Whiteside. (1996). Antitumor functions of natural killer cells and control of metastases. Methods 9:394-408.
3. Wallin RPA, V Screpanti, J Michaëlsson, A Grandien and H Ljunggren. (2003). Regulation of perforin-independent NK cell-mediated cytotoxicity. Eur J Immunol 33:2727-2735.
4. Screpanti V, RPA Wallin, A Grandien and H Ljunggren. (2005). Impact of FasL-induced apoptosis in the elimination of tumor cells by NK cells. Mol Immunol 42:495-499.
5. Smyth MJ, E Cretney, JM Kelly, JA Westwood, SEA Street, H Yagita, K Takeda, ALH van Dommelen, MA Degli-Esposti and Y Hayakawa. (2005). Activation of NK cell cytotoxicity. Mol Immunol 42:501-510.
6. Roggeri L, M Capanni, E Urbani, K Perruccio, WD Shlomchik, A Tosti, S Posati, D Rogaia, F Frassoni, F Aversa, MF Martelli and A Velardi. (2002). Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 295:2097-2100.
7. Whiteside TL and RB Herberman. (1995). The role of natural killer cells in immune surveillance. Curr Opin Immunol 7:704-710.
8. Carson W and M Caligiuri. (1996). Natural killer cell subsets and development. Methods 9:327-343.
9. Colucci F, MA Caligiuri and JP Di Santo. (2003). What does it take to make a natural killer. Nature Rev Immunol 3:413-425.
10. Gluckman E. (2000). Current status of umbilical cord blood hematopoietic stem cell transplantation. Exp Hematol 28:1197-1205.
11. Grewal SS, JN Barker, SM Davies and JE Wagner. (2003). Unrelated donor hematopoietic cell transplantation: marrow or umbilical cord blood. Blood 101:4233-4244.
12. - primitive progenitors in long-term bone marrow culture. Blood 80:2182-2187.
13. + hematopoietic progenitor cells. Blood 87:2632-2640.
14. + human natural killer cell progenitor that responds to interleukin-15. Blood 92:3647-3657.
15. Giarratana MC, V Verge, C Schmitt, JM Bertho, L Kobari, C Barret and Douay L. (2000). Presence of primitive lymphoid progenitors with NK or B potential in ex vivo expanded bone marrow cell cultures. Exp Hematol 28:46-54.
16. + cord blood cells. Exp Hematol 28:1470-1480.
17. + cell-derived NK cell cytotoxicity by dendritic cells. J Immunol 166:1590-1600.
18. + cell precursors towards NK cells and acquisition of surface killer Ig-like receptors. Eur J Immunol 33:3439-3447.
19. Nagamura-Inoue T, Y Mori, Z Yizhou, N Watanabe and TA Takahashi. (2004). Differential expansion of umbilical cord blood mononuclear cell-derived natural killer cells dependent on the dose of interleukin-15 with Flt3L. Exp Hematol 32:202-209.
20. Cavazzana-Calvo M, S Hacein-Bey, G De Saint Basile, C De Coene, F Selz, F Le Deist and A Fischer. (1996). Role of interleukin-2 (IL-2), IL-7, and IL-15 in natural killer cell differentiation from cord blood hematopoietic progenitor cells and from γc transduced severe combined immunodeficiency X1 bone marrow cells. Blood 88:3901-3909.
21. Fehniger TA and MA Caligiuri. (2001). Interleukin 15: biology and relevance to human disease. Blood 97:14-32.
22. Nguyen QH, RL Roberts, BJ Ank, SJ Lin, EK Thomas and ER Stiehm. (1998). Interleukin (IL)-15 enhances antibody-dependent cellular cytotoxicity and natural killer activity in neonatal cells. Cell Immunol 185:83-92.
23. Yao CL, CH Liu, IM Chu, TB Hsieh and SM Hwang. (2003). Factorial designs combined with the steepest ascent method to optimize serum-free media for ex vivo expansion of human hematopoietic progenitor cells. Enzyme Microb Technol 33:343-352.
24. Yao CL, IM Chu, TB Hsieh and SM Hwang. (2004). A systematic strategy to optimize ex vivo expansion medium for human hematopoietic stem cells derived from umbilical cord blood mononuclear cells. Exp Hematol 32:720-727.
25. + cells. Stem Cells Dev 15:70-78.
26. + cell determination by flow cytometry. J Hematother 5:231-239.
27. Cooper MA, TA Fehniger and MA Caligiuri. (2001). The biology of human natural killer-cell subsets. Trends Immunol 22:633-640.
28. + natural killer cells after bone marrow transplantation. Blood 79:3239-3244.
29. Carayol G, C Robin, J Bourhis, A Bennaceur-Griscelli, S Chouaib, L Coulombel and A Caignard. (1998). NK cells differentiated from bone marrow, cord blood and peripheral blood stem cells exhibit similar phenotype and functions. Eur J Immunol 28:1991-2002.
30. Perez SA, PA Sotiropoulou, DG Gkika, LG Mahaira, DK Niarchos, AD Gritzapis, YG Kavalakis, AI Antsaklis, CN Baxevanis and M Papamichail. (2003). A novel myeloid-like NK cell progenitor in umbilical cord blood. Blood 101:3444-3450.
31. Muench MO, L Humeau, B Peak, T Ohkubo, LL Lanier, CT Albanese and A Bárcena. (2000). Differential effects of interleukin-3, interleukin-7, interleukin-15, and granulocyte-macrophage colony-stimulating factor in the generation of natural killer and B cells from primitive human fetal liver progenitors. Exp Hematol 28:961-973.
32. + cells with antiproliferative effects on tumor cell lines. J Transl Med 3:15-22.