Synthesis of 4-alkynylpyrrolo[2,3-d]pyrimidines by palladium-catalyzed cross-coupling reactions

Synthesis

Volumn , Issue 24, 2007, Pages 3815-3820

  Tumkevicius, Sigitas ^a   Masevicius, Viktoras ^a  

^a VILNIUS UNIVERSITY   (Lithuania)

Author keywords

Alkyne; Catalysis; Cyclization; Heterocycle; Palladium; Pyrrolopyrimidine

Indexed keywords

CROSS COUPLING REACTIONS; HETEROCYCLES; PYRROLOPYRIMIDINES; TERMINAL ALKYNES;

CATALYSIS; CYCLIZATION; PALLADIUM; REACTION KINETICS; SYNTHESIS (CHEMICAL);

AMINO ACIDS;

2 ETHYNYL N MESYLANILINE; 4 (INDOL 2 YL)PYRROLO[2,3 D]PYRIMIDINE DERIVATIVE; 4 IODOPYRROLOPYRIMIDINE; ANILINE DERIVATIVE; COPPER; METHYL 5 AMINO 4 (1H INDOL 2 YL) 7 METHYL 2 (METHYLSULFANYL) 7H PYRROLO[2,3 D]PYRIMIDINE 6 CARBOXYLATE; METHYL 5 AMINO 4 (3 HYDROXYPROP 1 YNYL) 7 METHYL 2 (METHYLSULFANYL) 7H PYRROLO[2,3 D]PYRIMIDINE 6 CARBOXYLATE; METHYL 5 AMINO 4 [(2 AMINOPHENYL)ETHYNYL] 7 METHYL 2 (METHYLSULFANYL) 7H PYRROLO[2,3 D]PYRIMIDINE 6 CARBOXYLATE; METHYL 5 AMINO 4 [(4 FLUOROPHENYL)ETHYNYL] 7 METHYL 2 (METHYLSULFANYL) 7H PYRROLO[2,3 D]PYRIMIDINE 6 CARBOXYLATE; METHYL 5 AMINO 4 [[2 (ETHOXYCARBONYLAMINO)PHENYL]ETHYNYL] 7 METHYL 2 (METHYLSULFANYL) 7H PYRROLO[2,3 D]PYRIMIDINE 6 CARBOXYLATE; METHYL 5 AMINO 4 ETHYNYL 7 METHYL 2 (METHYLSULFANYL) 7H PYRROLO[2,3 D]PYRIMIDINE 6 CARBOXYLATE; METHYL 5 AMINO 4 HEX 1 YNYL 7 METHYL 2 (METHYLSULFANYL) 7H PYRROLO[2,3 D]PYRIMIDINE 6 CARBOXYLATE; METHYL 5 AMINO 7 METHYL 2 (METHYLSULFANYL) 4 (PHENYLETHYNYL) 7H PYRROLO[2,3 D]PYRIMIDINE 6 CARBOXYLATE; METHYL 5 AMINO 7 METHYL 2 (METHYLSULFANYL) 4 [(TRIMETHYLSILYL)ETHYNYL] 7H PYRROLO[2,3 D]PYRIMIDINE 6 CARBOXYLATE; METHYL 5 AMINO 7 METHYL 4 [(4 METHYLPHENYL)ETHYNYL] 2 (METHYLSULFANYL) 7H PYRROLO[2,3 D]PYRIMIDINE 6 CARBOXYLATE; PALLADIUM; PYRIMIDINE DERIVATIVE; PYRROLOPYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CROSS COUPLING REACTION; CYCLIZATION; SONOGASHIRA REACTION; SYNTHESIS;

EID: 37549022976     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-990882     Document Type: Article

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