Role of minor histocompatibility antigens in renal transplantation

American Journal of Transplantation

Volumn 8, Issue 1, 2008, Pages 95-102

  Heinold, A ^a   Opelz, G ^a   Scherer, S ^a   Ruhenstroth, A ^a   Laux, G ^a   Doehler, B ^a   Tran, T H ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Genetic polymorphism; Kidney graft survival

Indexed keywords

DNA; HLA A ANTIGEN; HLA B ANTIGEN; HLA DR ANTIGEN; MINOR HISTOCOMPATIBILITY ANTIGEN;

ANTIGEN DETECTION; ARTICLE; CONTROLLED STUDY; GENE FREQUENCY; GRAFT SURVIVAL; HISTOCOMPATIBILITY; HLA TYPING; HUMAN; HUMAN TISSUE; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

GENE FREQUENCY; GRAFT SURVIVAL; GRAFT VS HOST DISEASE; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; IMMUNOPHENOTYPING; KIDNEY TRANSPLANTATION; MINOR HISTOCOMPATIBILITY ANTIGENS; RETROSPECTIVE STUDIES;

EID: 37549020749     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2007.02042.x     Document Type: Article

References (43)

1. Opelz G for the Collaborative Transplant Study. Non-HLA transplantation immunity revealed by lymphocytotoxic antibodies. Lancet 2005 365 : 1570 1576.
2. Terasaki PI. Deduction of the fraction of immunologic and non-immunologic failure in cadaver donor transplants. In : Cecka JM, Terasaki PI, eds. Clinical transplants. Los Angeles, CA : UCLA Tissue Typing Laboratory, 2003 : 449 452.
3. Wallny HJ, Rammensee HG. Identification of classical minor histocompatibility antigen as cell-derived peptide. Nature 1990 343 : 275 278.
4. Loveland B, Wang CR, Yonekawa H, Hermel E, Lindahl KF. Maternally transmitted histocompatibility antigen of mice: A hydrophobic peptide of a mitochondrially encoded protein. Cell 1990 60 : 971 980.
5. Rotzschke O, Falk K, Wallny HJ, Faath S, Rammensee HG. Characterization of naturally occurring minor histocompatibility peptides including H-4 and H-Y. Science 1990 249 : 283 287.
6. Falk K, Rotzschke O, Rammensee HG. Cellular peptide composition governed by major histocompatibility complex class I molecules. Nature 1990 348 : 248 251.
7. Spierings E, Brickner AG, Caldwell JA et al. The minor histocompatibility antigen HA-3 arises from differential proteasome-mediated cleavage of the lymphoid blast crisis (Lbc) oncoprotein. Blood 2003 102 : 621 629.
8. den Haan JM, Meadows LM, Wang W et al. The minor histocompatibility antigen HA-1: A diallelic gene with a single amino acid polymorphism. Science 1998 279 : 1054 1057.
9. den Haan JM, Sherman NE, Blokland E et al. Identification of a graft versus host disease-associated human minor histocompatibility antigen. Science 1995 268 : 1476 1480.
10. Brickner AG, Warren EH, Caldwell JA et al. The immunogenicity of a new human minor histocompatibility antigen results from differential antigen processing. J Exp Med 2001 193 : 195 206.
11. Akatsuka Y, Nishida T, Kondo E et al. Identification of a polymorphic gene, BCL2A1, encoding two novel hematopoietic lineage-specific minor histocompatibility antigens. J Exp Med 2003 197 : 1489 1500.
12. Dolstra H, Fredrix H, Maas F et al. A human minor histocompatibility antigen specific for B cell acute lymphoblastic leukemia. J Exp Med 1999 189 : 301 308.
13. Murata M, Warren EH, Riddell SR. A human minor histocompatibility antigen resulting from differential expression due to a gene deletion. J Exp Med 2003 197 : 1279 1289.
14. Krishnan NS, Higgins RM, Lam FT et al. HA-1 mismatch has significant effect in chronic allograft nephropathy in clinical renal transplantation. Transplant Proc 2007 39 : 1439 1445.
15. Goulmy E, Gratama JW, Blokland E, Zwaan FE, van Rood JJ. A minor transplantation antigen detected by MHC-restricted cytotoxic T lymphocytes during graft-versus-host disease. Nature 1983 302 : 159 161.
16. Goulmy E, Schipper R, Pool J et al. Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host disease after bone marrow transplantation. N Engl J Med 1996 334 : 323 324.
17. Goulmy E, Termijtelen A, Bradley BA, van Rood JJ. Alloimmunity to human H-Y. Lancet 1976 2 : 1206.
18. Marijt WA, Heemskerk MH, Kloosterboer FM et al. Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemia. Proc Natl Acad Sci USA 2003 100 : 2742 2747.
19. Koulack J, McAlister VC, MacAulay MA, Bitter-Suermann H, MacDonald AS, Lee TD. Importance of minor histocompatibility antigens in the development of allograft arteriosclerosis. Clin Immunol Immunopathol 1996 80 : 273 277.
20. Yang J, Jaramillo A, Liu W et al. Chronic rejection of murine cardiac allografts discordant at the H13 minor histocompatibility antigen correlates with the generation of the H13-specific CD8+ cytotoxic T cells. Transplantation 2003 15 76 : 84 91.
21. Poindexter N, Shenoy S, Howard T, Flye MW, Mohanakumar T. Allograft infiltrating cytotoxic T lymphocytes recognize kidney-specific human minor histocompatibility antigens. Clin Transplant 1997 11 : 174 177.
22. Bonneville M, Moreau JF, Blokland E et al. lymphocyte cloning from rejected human kidney allograft. Recognition repertoire of alloreactive T cell clones. J Immunol 1988 141 : 4187 4195.
23. Pfeffer PF, Thorsby E. HLA-restricted cytotoxicity against male-specific (H-Y) antigen after acute rejection of an HLA-identical sibling kidney: Clonal distribution of the cytotoxic cells. Transplantation 1982 33 : 52 56.
24. Cai J, Lee J, Jankowska-Gan E et al. Minor H antigen HA-1-specific regulator and effector CD8+ T cells, and HA-1 microchimerism, in allograft tolerance. J Exp Med 2004 199 : 1017 1023.
25. Graham DE. The isolation of high molecular weight DNA from whole organisms or large tissue masses. Anal Biochem 1978 85 : 609 613.
26. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988 16 : 1215.
27. Goulmy E, Schipper R, Pool J et al. Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host disease after bone marrow transplantation. N Engl J Med 1996 334 : 281 285.
28. Nishida T, Akatsuka Y, Morishima Y et al. Clinical relevance of a newly identified HLA-A24-restricted minor histocompatibility antigen epitope derived from BCL2A1, ACC-1, in patients receiving HLA genotypically matched unrelated bone marrow transplant. Br J Haematol 2004 124 : 629 635.
29. Akatsuka Y, Warren EH, Gooley TA et al. Disparity for a newly identified minor histocompatibility antigen, HA-8, correlates with acute graft-versus-host disease after haematopoietic stem cell transplantation from an HLA-identical sibling. Br J Haematol 2003 123 : 671 675.
30. Perez-Garcia A, De la Camara R, Torres A, Gonzalez M, Jimenez A, Gallardo D. Minor histocompatibility antigen HA-8 mismatch and clinical outcome after HLA-identical sibling donor allogeneic stem cell transplantation. Haematologica 2005 90 : 1723 1724.
31. Tseng LH, Lin MT, Hansen JA et al. Correlation between disparity for the minor histocompatibility antigen HA-1 and the development of acute graft-versus-host disease after allogeneic marrow transplantation. Blood 1999 94 : 2911 2914.
32. Gallardo D, Arostegui JI, Balas A et al. Disparity for the minor histocompatibility antigen HA-1 is associated with an increased risk of acute graft-versus-host disease (GvHD) but it does not affect chronic GvHD incidence, disease-free survival or overall survival after allogeneic human leucocyte antigen-identical sibling donor transplantation. Br J Haematol 2001 114 : 931 936.
33. Spierings E, Goulmy E. Expanding the immunotherapeutic potential of minor histocompatibility antigens. J Clin Invest 2005 115 : 3397 3400.
34. Cao K, Hollenbach J, Shi X, Shi W, Chopek M, Fernandez-Vina MA. Analysis of the frequencies of HLA-A,B,C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations. Hum Immunol 2001 62 : 109 130.
35. Sidney J, Grey HM, Kubo RT, Sette A. Practical, biochemical and evolutionary implications of the discovery of HLA class I supermotifs. Immunol Today 1996 17 : 261 266.
36. Sette A, Sidney J. HLA supertypes and supermotifs: A functional perspective on HLA polymorphism. Curr Opin Immunol 1998 10 : 478 482.
37. Sette A, Sidney J. Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism. Immunogenetics 1999 50 : 201 212.
38. Sidney J, Southwood S, Sette A. Classification of A1- and A24-supertype molecules by analysis of their MHC-peptide binding repertoires. Immunogenetics 2005 57 : 393 408.
39. del Guercio MF, Sidney J, Hermanson G et al. Binding of a peptide antigen to multiple HLA alleles allows definition of an A2-like supertype. J Immunol 1995 154 : 685 693.
40. Torikai H, Akatsuka Y, Miyauchi H et al. The HLA-A(*)0201- restricted minor histocompatibility antigen HA-1(H) peptide can also be presented by another HLA-A2 subtype, A(*)0206. Bone Marrow Transplant 2007 40 : 165 174.
41. Voogt PJ, Fibbe WE, Marijt WA et al. Rejection of bone-marrow graft by recipient-derived cytotoxic T lymphocytes against minor histocompatibility antigens. Lancet 1990 335 : 131 134.
42. Reddy P, Ferrara JL. Immunobiology of acute graft-versus-host disease. Blood Rev 2003 17 : 187 194.
43. Terakura S, Murata M, Warren EH, Sette A, Naoe T, Riddell SR. A single minor histocompatibility antigen AELLNIPFLY encoded by UGT2B17 is presented by HLA-A*2902, B*4402 and B*4403. Biol Blood Marrow Transplant 2006 12 (Suppl. 1 3 4.