Fas expression is associated with a better prognosis in laryngeal squamous cell carcinoma

Anticancer Research

Volumn 27, Issue 6 B, 2007, Pages 4083-4086

  Asensio, Carlos ^a   Zapata, Ana ^a   García Ahijado, Jesús ^a   Gil, Braulio ^a   Salvadores, Paloma ^b   Schneider, José ^b  

^a HOSPITAL NUESTRA SEÑORA DEL PRADO   (Spain)

^b UNIVERSIDAD REY JUAN CARLOS   (Spain)

Author keywords

Bcl 2; Cancer; Fas; Immunohistochemistry; Larynx; p53

Indexed keywords

FAS ANTIGEN; PROTEIN BCL 2; PROTEIN P53;

ARTICLE; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LARYNX CARCINOMA; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD95; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; HUMANS; IMMUNOHISTOCHEMISTRY; LARYNGEAL NEOPLASMS; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-BCL-2; SURVIVAL RATE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 37549010239     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Sharma K, Wang RX, Zhang LY, Yin DL, Luo XY, Solomon JC, Jiang RF, Markos K, Davidson W, Scott DW and Shi YF: Death the Fas way: regulation and pathophysiology of CD95 and its ligand. Pharmacol Ther 88: 333-347, 2000.
2. Kumar S, Walia V, Ray M and Elble RC: p53 in breast cancer: mutation and countermeasures. Front Biosci 12: 4168-4178, 2007.
3. Schneider J, Pollan M, Tejerina A, Sanchez J and Lucas AR: Accumulation of uPA-PAI-1 complexes inside the tumour cells is associated with axillary nodal invasion in progesterone-receptor-positive early breast cancer. Br J Cancer 88: 96-101, 2003.
4. Agudo D, Gomez-Esquer F, Martinez-Arribas F, Nuñez-Villar MJ, Pollan M and Schneider J: Nup88-mRNA overexpression is associated with high aggressiveness of breast cancer. Int J Cancer 109: 717-720, 2004.
5. Martinez-Arribas F, Alvarez T, Del Val G, Martin-Garabato E, Nuñez-Villar MJ, Lucas R, Sanchez J, Tejerina A and Schneider J: Bcl-2 expression in breast cancer: a comparative study at the mRNA and protein level. Anticancer Res 27: 219-222, 2007.
6. Schneider J, Rubio MP, Rodríguez-Escudero FJ, Seizinger BS and Castresana JS: Identification of p53 mutations by means of SSCP (single strand conformation polymorphism) analysis in gynaecologic tumors: comparison with the results of imunohistochemistry. Eur J Cancer 30A: 504-508, 1994.
7. Jäckel MC, Mitteldorf C, Schweyer S and Fuzesi L: Clinical relevance of Fas (APO-1/CD95) expression in laryngeal squamous cell carcinoma. Head Neck 23: 646-652, 2001.
8. Chan KW, Lee PY, Lam AKY, Law S, Wong J and Srivastava G: Clinical relevance of Fas expression in oesophageal squamous cell carcinoma. J Clin Pathol 59: 101-104, 2006.
9. Hirvikoski P, Kumpulainen E, Virtaniemi J, Pirinen R, Salmi L, Halonen P, Johansson R and Kosma VM: Enhanced apoptosis correlates with poor survival in patients with laryngeal cancer but not with cell proliferation, bcl-2 or p53 expression. Eur J Cancer 35: 231-237, 1999.
10. Jäckel MC, Sellmann L, Dorudian MA, Youssef S and Fuzesi L: Prognostic significance of p53/bcl-2 co-expression in patients with laryngeal squamous cell carcinoma. Laryngoscope 110: 1339-1345, 2000.
11. Georgiou A, Gomatos IP, Pararas NB, Giotakis J and Ferekidis E: Cell kinetics and apoptosis in laryngeal carcinoma patients. Ann Otol Rhinol Laryngol 112: 206-213, 2003.
12. Assimakopoulos D, Kolettas E, Zagorianakou N, Evangelou A, Skevas A and Agnantis NJ: Prognostic significance of p53 in the cancer of the larynx. Anticancer Res 20: 3555-3564, 2000.
13. Teppo H, Soini Y, Melkko J, Koivunen P and Alho OP: Prognostic factors in laryngeal carcinoma: the role of apoptosis, p53, proliferation (Ki67) and angiogenesis. APMIS 111: 451-457, 2003.
14. Pizem J, Cor A and Gale N: Survivin expression is a negative prognostic marker in laryngeal squamous cell carcinoma and is associated with p53 accumulation. Histopathology 45: 180-186, 2004.