Drosophila Follistatin exhibits unique structural modifications and interacts with several TGF-β family members

Mechanisms of Development

Volumn 125, Issue 1-2, 2008, Pages 117-129

  Bickel, Daniela ^a   Shah, Ripal ^a   Gesualdi, Scott C ^a   Haerry, Theodor E ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

Dawdle; DPP; Drosophila activin; Follistatin; Growth control; Heparin sulfate; Myoglianin; TGF

Indexed keywords

ACTIVIN; DECAPENTAPLEGIC PROTEIN; FOLLISTATIN; TRANSFORMING GROWTH FACTOR BETA;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DROSOPHILA; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; DROSOPHILA; FOLLISTATIN; HYDROLYSIS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIGANDS; PHENOTYPE; PROTEIN BINDING; PROTEIN CONFORMATION; TRANSFORMING GROWTH FACTOR BETA;

VERTEBRATA;

EID: 37449034106     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mod.2007.09.013     Document Type: Article

References (33)

1. Abe Y., Minegishi T., and Leung P.C. Activin receptor signaling. Growth Factors 22 (2004) 105-110
2. Beattie G.M., Lopez A.D., Bucay N., Hinton A., Firpo M.T., King C.C., and Hayek A. Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers. Stem Cells 23 (2005) 489-495
3. Brand A.H., and Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118 (1993) 401-415
4. Canalis E., Economides A.N., and Gazzerro E. Bone morphogenetic proteins, their antagonists, and the skeleton. Endocr. Rev. 24 (2003) 218-235
5. Cavener D.R. Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates. Nucleic Acids Res. 15 (1987) 1353-1361
6. Colavita A., Krishna S., Zheng H., Padgett R.W., and Culotti J.G. Pioneer axon guidance by UNC-129, a C. elegans TGF-β. Science 281 (1998) 706-709
7. de Celis J.F., Barrio R., and Kafatos F.C. A gene complex acting downstream of dpp in Drosophila wing morphogenesis. Nature 381 (1996) 421-424
8. Gesualdi S.C., and Haerry T.E. Distinct signaling of Drosophila activin/TGF-β family members. Fly 1 (2007) 212-221
9. Haerry T.E., Khalsa O., O'Connor M.B., and Wharton K.A. Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila. Development 125 (1998) 3977-3987
10. Haerry T.E., and O'Connor M.B. Isolation of Drosophila Activin and Follistatin cDNAs using novel MACH amplification protocols. Gene 291 (2002) 85-93
11. Ho T.W., Bristol L.A., Coccia C., Li Y., Milbrandt J., Johnson E., Jin L., Bar-Peled O., Griffin J.W., and Rothstein J.D. TGFbeta trophic factors differentially modulate motor axon outgrowth and protection from excitotoxicity. Exp. Neurol. 161 (2000) 664-675
12. Innis C.A., and Hyvonen M. Crystal structures of the heparan sulfate-binding domain of follistatin. Insights into ligand binding. J. Biol. Chem. 278 (2003) 39969-39977
13. Inouye S., Ling N., and Shimasaki S. Localization of the heparin binding site of follistatin. Mol. Cell Endocrinol. 90 (1992) 1-6
14. James D., Levine A.J., Besser D., and Hemmati-Brivanlou A. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 132 (2005) 1273-1282
15. Jazwinska A., Rushlow C., and Roth S. The role of brinker in mediating the graded response to Dpp in early Drosophila embryos. Development 126 (1999) 3323-3334
16. Khokha M.K., Yeh J., Grammer T.C., and Harland R.M. Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures. Dev. Cell 8 (2005) 401-411
17. Kutty G., Kutty R.K., Samuel W., Duncan T., Jaworski C., and Wiggert B. Identification of a new member of transforming growth factor-β superfamily in Drosophila: the first invertebrate activin gene. Biochem. Biophys. Res. Commun. 246 (1998) 644-649
18. Lo P.C., and Frasch M. Sequence and expression of myoglianin, a novel Drosophila gene of the TGF-β superfamily. Mech. Dev. 86 (1999) 171-175
19. Mason E.D., Konrad K.D., Webb C.D., and Marsh J.L. Dorsal midline fate in Drosophila embryos requires twisted gastrulation, a gene encoding a secreted protein related to human connective tissue growth factor. Genes Dev. 8 (1994) 1489-1501
20. Massague J., Blain S.W., and Lo R.S. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 103 (2000) 295-309
21. Matzuk M.M., Lu N., Vogel H., Sellheyer K., Roop D.R., and Bradley A. Multiple defects and perinatal death in mice deficient in follistatin. Nature 374 (1995) 360-363
22. McCabe B.D., Marques G., Haghighi A.P., Fetter R.D., Crotty M.L., Haerry T.E., Goodman C.S., and O'Connor M.B. The BMP homolog Gbb provides a retrograde signal that regulates synaptic growth at the Drosophila neuromuscular junction. Neuron 39 (2003) 241-254
23. Muller B., Hartmann B., Pyrowolakis G., Affolter M., and Basler K. Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient. Cell 113 (2003) 221-233
24. Newfeld S.J., Wisotzkey R.G., and Kumar S. Molecular evolution of a developmental pathway: phylogenetic analyses of transforming growth factor-β family ligands, receptors and Smad signal transducers. Genetics 152 (1999) 783-795
25. Nguyen M., Park S., Marques G., and Arora K. Interpretation of a BMP activity gradient in Drosophila embryos depends on synergistic signaling by two type I receptors, SAX and TKV. Cell 95 (1998) 495-506
26. Rooke H.M., and Crosier K.E. The smad proteins and TGFbeta signalling: uncovering a pathway critical in cancer. Pathology 33 (2001) 73-84
27. Schneyer A.L., Wang Q., Sidis Y., and Sluss P.M. Differential distribution of follistatin isoforms: application of a new FS315-specific immunoassay. J. Clin. Endocrinol. Metab. 89 (2004) 5067-5075
28. Shimmi O., Umulis D., Othmer H., and O'Connor M.B. Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo. Cell 120 (2005) 873-886
29. Taghert P.H., Hewes R.S., Park J.H., O'Brien M.A., Han M., and Peck M.E. Multiple amidated neuropeptides are required for normal circadian locomotor rhythms in Drosophila. J. Neurosci. 21 (2001) 6673-6686
30. Thompson T.B., Lerch T.F., Cook R.W., Woodruff T.K., and Jardetzky T.S. The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding. Dev. Cell 9 (2005) 535-543
31. Umulis D.M., Serpe M., O'Connor M.B., and Othmer H.G. Robust, bistable patterning of the dorsal surface of the Drosophila embryo. Proc. Natl. Acad. Sci. USA 103 (2006) 11613-11618
32. Wodarz A., Hinz U., Engelbert M., and Knust E. Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila. Cell 82 (1995) 67-76
33. Yasuo H., and Lemaire P. Generation of the germ layers along the animal-vegetal axis in Xenopus laevis. Int. J. Dev. Biol. 45 (2001) 229-235