메뉴 건너뛰기




Volumn 14, Issue 6, 2007, Pages 204-210

Trazadone associated with SSRIs and SNRIs in depressed patients with anxiety and insomnia;Trazodona combinada con ISRS e ISRN en pacientes deprimidos que presentan ansiedad e insomnio

Author keywords

Anxiety; Depression; Insomnia; SNRIs; SSRIs; Trazodone

Indexed keywords

CITALOPRAM; DULOXETINE; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; NORADRENALIN UPTAKE INHIBITOR; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRAZODONE; VENLAFAXINE;

EID: 37349128941     PISSN: 11345934     EISSN: 15788962     Source Type: Journal    
DOI: 10.1016/S1134-5934(07)73286-4     Document Type: Article
Times cited : (1)

References (53)
  • 2
    • 0031917424 scopus 로고    scopus 로고
    • Basic psychopharmacology af antidepressants, part 1: Antidepressants have seven distinct mechanisms of action
    • Stahl SM. Basic psychopharmacology af antidepressants, part 1: antidepressants have seven distinct mechanisms of action. J Clin Psychiatry. 1998;59 Suppl 4:5-24.
    • (1998) J Clin Psychiatry , vol.59 , Issue.SUPPL. 4 , pp. 5-24
    • Stahl, S.M.1
  • 3
    • 85031443485 scopus 로고    scopus 로고
    • Furlan PM, Picci RL, Lazaarini R, et al. Trazodone: metanalisi dei dati di efficacia nel trattamento della depressione e nuove prospettive terapeutiche. Proceedings of the Congress Farmaci Innovativi: gli Antidepressivi. Roma: Istututo Superiore di Sanità; 2003.
    • Furlan PM, Picci RL, Lazaarini R, et al. Trazodone: metanalisi dei dati di efficacia nel trattamento della depressione e nuove prospettive terapeutiche. Proceedings of the Congress "Farmaci Innovativi: gli Antidepressivi". Roma: Istututo Superiore di Sanità; 2003.
  • 4
    • 0026534291 scopus 로고
    • The comparative efficacy of trazodone and imipramine in the treatment of depression
    • Patten SB. The comparative efficacy of trazodone and imipramine in the treatment of depression. Can Med Assoc J. 1992;146:1177-82.
    • (1992) Can Med Assoc J , vol.146 , pp. 1177-1182
    • Patten, S.B.1
  • 5
    • 0019136727 scopus 로고
    • Trazodone in the treatment of neurotic depression
    • Goldberg HL, Finnerty RJ. Trazodone in the treatment of neurotic depression. J Clin Psychiatry 1980;41:430-4.
    • (1980) J Clin Psychiatry , vol.41 , pp. 430-434
    • Goldberg, H.L.1    Finnerty, R.J.2
  • 6
    • 0025836244 scopus 로고
    • Fluoxetine versus trazodone: Efficacy and activating-sedating effects
    • Beasley CM Jr, Dornself BE, Pultz JA, et al. Fluoxetine versus trazodone: efficacy and activating-sedating effects. J Clin Psychiatry. 1991;52:294-9.
    • (1991) J Clin Psychiatry , vol.52 , pp. 294-299
    • Beasley Jr, C.M.1    Dornself, B.E.2    Pultz, J.A.3
  • 7
    • 23744489246 scopus 로고    scopus 로고
    • A clinical phase III study of SME3110 (fluoxetine maleate) in depressed patients at the Department of Internal Medicine. A double blind, comparative study with trazodone hydrochloride
    • Namiki M, Eiji M, Minemoto H, et al. A clinical phase III study of SME3110 (fluoxetine maleate) in depressed patients at the Department of Internal Medicine. A double blind, comparative study with trazodone hydrochloride. J Clin Psychiatry. 1996;12:651-77.
    • (1996) J Clin Psychiatry , vol.12 , pp. 651-677
    • Namiki, M.1    Eiji, M.2    Minemoto, H.3
  • 8
    • 23744484123 scopus 로고    scopus 로고
    • A comparative, randomised, double-blind study of trazodone prolonged-release and paroxetine in the treatment of patients with major depressive disorder
    • Kasper S, Olivieri L, Di Loreto G, et al. A comparative, randomised, double-blind study of trazodone prolonged-release and paroxetine in the treatment of patients with major depressive disorder. Curr Med Res Opin. 2005;21:1139-46.
    • (2005) Curr Med Res Opin , vol.21 , pp. 1139-1146
    • Kasper, S.1    Olivieri, L.2    Di Loreto, G.3
  • 9
    • 0030836731 scopus 로고    scopus 로고
    • A clinical evaluation of sertraline hydrochloride, a selective serotonin reuptake inhibitor, in the treatment of depression and depressive state
    • Tsutsui SA, Okuse S, Sasaki D, et al. A clinical evaluation of sertraline hydrochloride, a selective serotonin reuptake inhibitor, in the treatment of depression and depressive state. Jpn J Neuropsychopharmacol. 1997;19:549-68.
    • (1997) Jpn J Neuropsychopharmacol , vol.19 , pp. 549-568
    • Tsutsui, S.A.1    Okuse, S.2    Sasaki, D.3
  • 10
    • 35348944082 scopus 로고    scopus 로고
    • A meta-analysis of clinical trials comparing the serotonin (5HT)-2 receptor antagonists trazodone and nefazodone with selective serotonin reuptake inhibitors for the treatment of major depressive disorder
    • Papakostas G, Fava M. A meta-analysis of clinical trials comparing the serotonin (5HT)-2 receptor antagonists trazodone and nefazodone with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. Eur Psychiatry. 2007;22:444-7.
    • (2007) Eur Psychiatry , vol.22 , pp. 444-447
    • Papakostas, G.1    Fava, M.2
  • 11
    • 0031303384 scopus 로고    scopus 로고
    • Depressive disorder in pre-adolescence: Comorbidity or different clinical subtypes? (A pharmacological contribution)
    • Levi G. Depressive disorder in pre-adolescence: comorbidity or different clinical subtypes? (A pharmacological contribution). Isr J Psychiatry Relat Sci 1997;34:187-94.
    • (1997) Isr J Psychiatry Relat Sci , vol.34 , pp. 187-194
    • Levi, G.1
  • 12
    • 0027365016 scopus 로고
    • Antidepressants for the treatment of generalized anxiety disorder. A placebo-controlled comparison of imipramine, trazodone, and diazepam
    • Rickels K. Antidepressants for the treatment of generalized anxiety disorder. A placebo-controlled comparison of imipramine, trazodone, and diazepam. Arch Gen Psychiatry. 1993;50:884-95.
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 884-895
    • Rickels, K.1
  • 13
    • 85031434860 scopus 로고    scopus 로고
    • Stella S. L'uso del trazodone per via endovenosa: uno studio clinico. Rivista di Psichiatria. 2001;35:1-7.
    • Stella S. L'uso del trazodone per via endovenosa: uno studio clinico. Rivista di Psichiatria. 2001;35:1-7.
  • 14
    • 0031026215 scopus 로고    scopus 로고
    • A double-blind comparison of trazodone and haloperidol for treatment of agitation in patients with dementia
    • Sulzer DL. A double-blind comparison of trazodone and haloperidol for treatment of agitation in patients with dementia. Am J Geriatr Psychiatry. 1997;5:60-9.
    • (1997) Am J Geriatr Psychiatry , vol.5 , pp. 60-69
    • Sulzer, D.L.1
  • 15
    • 0026803428 scopus 로고
    • and chronic administration of trazodone in the treatment of disruptive behavior disorders in children
    • Zubieta JK. Acute and chronic administration of trazodone in the treatment of disruptive behavior disorders in children. J Clin Psychopharmacol. 1992;12:346-51.
    • (1992) J Clin Psychopharmacol , vol.12 , pp. 346-351
    • Acute, Z.J.K.1
  • 16
    • 0027194880 scopus 로고
    • Trazodone in benzodiazepine dependence
    • Ansseau M. Trazodone in benzodiazepine dependence. J Clin Psychiatry. 1993;54:189-91.
    • (1993) J Clin Psychiatry , vol.54 , pp. 189-191
    • Ansseau, M.1
  • 17
    • 0032909592 scopus 로고    scopus 로고
    • Trazodone and valproate in patients discontinuing long-term benzodiazepine therapy: Effects on withdrawal symptoms and taper outcome
    • Rickels K. Trazodone and valproate in patients discontinuing long-term benzodiazepine therapy: effects on withdrawal symptoms and taper outcome. Psychopharmacology (Berl). 1999;141:1-5.
    • (1999) Psychopharmacology (Berl) , vol.141 , pp. 1-5
    • Rickels, K.1
  • 18
    • 0031848978 scopus 로고    scopus 로고
    • Adjuvant trazodone in the treatment of alcoholism: An open study
    • Janiri L. Adjuvant trazodone in the treatment of alcoholism: an open study. Alcohol Alcohol. 1998;33:362-5.
    • (1998) Alcohol Alcohol , vol.33 , pp. 362-365
    • Janiri, L.1
  • 19
    • 0042133410 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study of the efficacy of trazodone in alcohol post-withdrawal syndrome: Polysomnographic and clinical evaluations
    • Le Bon O. Double-blind, placebo-controlled study of the efficacy of trazodone in alcohol post-withdrawal syndrome: polysomnographic and clinical evaluations. J Clin Psychopharmacol. 2003;23:377-83.
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 377-383
    • Le Bon, O.1
  • 20
    • 0041408820 scopus 로고    scopus 로고
    • Trazodone for erectile dysfunction: A systematic review and meta-analysis
    • Fink HA. Trazodone for erectile dysfunction: a systematic review and meta-analysis. BJU Int. 2003;92:441-6.
    • (2003) BJU Int , vol.92 , pp. 441-446
    • Fink, H.A.1
  • 21
    • 0022537627 scopus 로고
    • Increased libido in women receiving trazodone
    • Gartrell N. Increased libido in women receiving trazodone. Am J Psychiatry. 1986;143:781-2.
    • (1986) Am J Psychiatry , vol.143 , pp. 781-782
    • Gartrell, N.1
  • 22
    • 0028285257 scopus 로고
    • The efficacy of anti-serotoninergic agents in the treatment of erectile dysfunction
    • Kurt U. The efficacy of anti-serotoninergic agents in the treatment of erectile dysfunction. J Urol. 1994;152:407-9.
    • (1994) J Urol , vol.152 , pp. 407-409
    • Kurt, U.1
  • 23
    • 0028673621 scopus 로고
    • Effect of yohimbine-trazodone on psychogenic impotence: A randomized, double-blind, placebo-controlled study
    • Montorsi F. Effect of yohimbine-trazodone on psychogenic impotence: a randomized, double-blind, placebo-controlled study. Urology, 1994;44:732-6.
    • (1994) Urology , vol.44 , pp. 732-736
    • Montorsi, F.1
  • 24
    • 0026057834 scopus 로고
    • Pathophysiology of prolonged penile erection associated with trazodone use
    • Sáenz de Tejada I. Pathophysiology of prolonged penile erection associated with trazodone use. J Urol. 1991;145:60-4.
    • (1991) J Urol , vol.145 , pp. 60-64
    • Sáenz de Tejada, I.1
  • 25
    • 0028079752 scopus 로고
    • The acute effects of nefazodone, trazodone and buspirone on sleep and sleep-related penile tumescence in normal subjects
    • Ware JC. The acute effects of nefazodone, trazodone and buspirone on sleep and sleep-related penile tumescence in normal subjects. Sleep. 1994;17:544-50.
    • (1994) Sleep , vol.17 , pp. 544-550
    • Ware, J.C.1
  • 26
    • 0032822490 scopus 로고    scopus 로고
    • Antidepressant treatment of the depressed patient with insomnia
    • Thase ME. Antidepressant treatment of the depressed patient with insomnia. J Clin Psychiatry. 1999;60 Suppl 17:28-31.
    • (1999) J Clin Psychiatry , vol.60 , Issue.SUPPL. 17 , pp. 28-31
    • Thase, M.E.1
  • 27
    • 0020013481 scopus 로고
    • Pharmaco-EEG profiles of typical and atypical antidepressants
    • Costa E, Racagni G, editores, New York: Raven Press;
    • Saletu B. Pharmaco-EEG profiles of typical and atypical antidepressants. En: Costa E, Racagni G, editores. Typical and atypical antidepressants; clinical practice. New York: Raven Press; 1982. p. 257-68.
    • (1982) Typical and atypical antidepressants; clinical practice , pp. 257-268
    • Saletu, B.1
  • 28
    • 0031659471 scopus 로고    scopus 로고
    • Effects of trazodone hydrochloride and imipramine on polysomnography in healthy subjects
    • Yamadera H, Nakamura S, Suzuki H, et al. Effects of trazodone hydrochloride and imipramine on polysomnography in healthy subjects. Psychiatry Clin Neurosci. 1998;52:439-43.
    • (1998) Psychiatry Clin Neurosci , vol.52 , pp. 439-443
    • Yamadera, H.1    Nakamura, S.2    Suzuki, H.3
  • 29
    • 0020556153 scopus 로고
    • Trazodone enhances sleep in subjective quality but not in objective duration
    • Montgomery I, Oswald I, Morgan K, Adam K. Trazodone enhances sleep in subjective quality but not in objective duration. Br J Clin Pharmacol. 1983;16:139-44.
    • (1983) Br J Clin Pharmacol , vol.16 , pp. 139-144
    • Montgomery, I.1    Oswald, I.2    Morgan, K.3    Adam, K.4
  • 30
    • 7144226575 scopus 로고    scopus 로고
    • Subjective hypnotic efficacy of trazodone and zolpidem in DSMIII-R primary insomnia
    • Walsh JK, Erman M, Erwin CW, et al. Subjective hypnotic efficacy of trazodone and zolpidem in DSMIII-R primary insomnia. Hum Psychopharmacol Clin Exp. 1998;13:191-8.
    • (1998) Hum Psychopharmacol Clin Exp , vol.13 , pp. 191-198
    • Walsh, J.K.1    Erman, M.2    Erwin, C.W.3
  • 31
    • 0023946524 scopus 로고
    • Effect of trazodone on the sleep of depressed subjects -a polygraphic study
    • Mouret J, Lemoine P, Minuit MP, et al. Effect of trazodone on the sleep of depressed subjects -a polygraphic study. Psychopharmacology. 1988;95 Suppl:S37-43.
    • (1988) Psychopharmacology , vol.95 , Issue.SUPPL.
    • Mouret, J.1    Lemoine, P.2    Minuit, M.P.3
  • 32
    • 0028239991 scopus 로고
    • Trazodone for antidepressant-associated insomnia
    • Nierenberg AA, Adler LA, Peselow E, et al. Trazodone for antidepressant-associated insomnia. Am J Psychiatry. 1994;151:1069-72.
    • (1994) Am J Psychiatry , vol.151 , pp. 1069-1072
    • Nierenberg, A.A.1    Adler, L.A.2    Peselow, E.3
  • 33
    • 0033799105 scopus 로고    scopus 로고
    • Depression and sleep disorders: Clinical relevance, economic burden and pharmacological treatment
    • Brunello N, Armitage R, Feinberg I, et al. Depression and sleep disorders: Clinical relevance, economic burden and pharmacological treatment. Neuropsychobiology. 2000;42:107-19.
    • (2000) Neuropsychobiology , vol.42 , pp. 107-119
    • Brunello, N.1    Armitage, R.2    Feinberg, I.3
  • 34
    • 0033848645 scopus 로고    scopus 로고
    • Effects of selective serotonin reuptake inhibitors on objective and subjective sleep quality
    • Oberndorfer S, Saletu-Zyhlarz G, Saletu B. Effects of selective serotonin reuptake inhibitors on objective and subjective sleep quality. Neurophsychobioloby. 2000;42:69-81.
    • (2000) Neurophsychobioloby , vol.42 , pp. 69-81
    • Oberndorfer, S.1    Saletu-Zyhlarz, G.2    Saletu, B.3
  • 35
    • 0035741880 scopus 로고    scopus 로고
    • Insomnia related to dysthymia: Comparison with normal controls and acute therapeutic trials with trazodone
    • Saletu-Zyhlarz GM, Abu-Bakr MH, Anderer P, et al. Insomnia related to dysthymia: Comparison with normal controls and acute therapeutic trials with trazodone. Neuropsychobiology. 2001;44:139-49.
    • (2001) Neuropsychobiology , vol.44 , pp. 139-149
    • Saletu-Zyhlarz, G.M.1    Abu-Bakr, M.H.2    Anderer, P.3
  • 36
    • 0036137994 scopus 로고    scopus 로고
    • Insomnia in depression: Differences in objective and subjective sleep and awakening quality normal controls and acute effects of trazodone
    • Saletu-Zyhlarz GM, Abu-Bakr MH, Anderer P, et al. Insomnia in depression: Differences in objective and subjective sleep and awakening quality normal controls and acute effects of trazodone. Prog Neuropsychopharmacol Biol Bsychiatry. 2002;26:249-60.
    • (2002) Prog Neuropsychopharmacol Biol Bsychiatry , vol.26 , pp. 249-260
    • Saletu-Zyhlarz, G.M.1    Abu-Bakr, M.H.2    Anderer, P.3
  • 37
    • 0346749730 scopus 로고    scopus 로고
    • Confirmation of the neuropshysiolocally predicted therapeutics effects of trazodone on its target symptoms depression, anxiety and insomnia by postmarketing clinical studies with a controlled-release formulation in depressed outpatients
    • Saletu-Zyhlarz GM, Anderer P, Arnold O, Saletu B. Confirmation of the neuropshysiolocally predicted therapeutics effects of trazodone on its target symptoms depression, anxiety and insomnia by postmarketing clinical studies with a controlled-release formulation in depressed outpatients. Neuropsychobiology. 2003;48:194-208.
    • (2003) Neuropsychobiology , vol.48 , pp. 194-208
    • Saletu-Zyhlarz, G.M.1    Anderer, P.2    Arnold, O.3    Saletu, B.4
  • 38
    • 0026298515 scopus 로고
    • Toleration and safety of sertraline: Experience world-wide
    • Doogan DP. Toleration and safety of sertraline: experience world-wide. Int Clin Psychopharmacol. 1991;6 Suppl 2:47-56.
    • (1991) Int Clin Psychopharmacol , vol.6 , Issue.SUPPL. 2 , pp. 47-56
    • Doogan, D.P.1
  • 40
    • 0026795009 scopus 로고
    • Sertraline a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in depression and obsesive-compulsive disorder
    • Murdoch D, McTavish D. Sertraline a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in depression and obsesive-compulsive disorder. Drugs. 1992;44:604-24.
    • (1992) Drugs , vol.44 , pp. 604-624
    • Murdoch, D.1    McTavish, D.2
  • 41
    • 0033849889 scopus 로고    scopus 로고
    • A double-blind comparison of sertraline and fluoxetine in depressed elderly outpatients
    • Newhouse PA, Krishnan KRR, Doraiswamy PM, et al. A double-blind comparison of sertraline and fluoxetine in depressed elderly outpatients. J Clin Psychiatry. 2000;61;559-68.
    • (2000) J Clin Psychiatry , vol.61 , pp. 559-568
    • Newhouse, P.A.1    Krishnan, K.R.R.2    Doraiswamy, P.M.3
  • 42
    • 0029123999 scopus 로고
    • Drug utilization review of concomittant use of specific serotonin reuptake inhibitors or clomipramine with antianxiety/sleep medications
    • Rascertti K. Drug utilization review of concomittant use of specific serotonin reuptake inhibitors or clomipramine with antianxiety/sleep medications. Clin Ther. 1995;17:786-90.
    • (1995) Clin Ther , vol.17 , pp. 786-790
    • Rascertti, K.1
  • 43
    • 7044251991 scopus 로고    scopus 로고
    • Trazodone addition for insmonia in venlafaxine-treated depressed inpatients: A semi-naturalistic study
    • Bertschy G, Ragama-Pardos E, Muscionico M, et al. Trazodone addition for insmonia in venlafaxine-treated depressed inpatients: a semi-naturalistic study. Pharmacol Res. 2005;51:79-84.
    • (2005) Pharmacol Res , vol.51 , pp. 79-84
    • Bertschy, G.1    Ragama-Pardos, E.2    Muscionico, M.3
  • 44
    • 0014769731 scopus 로고
    • Evaluación estadística y adaptación castellana de la escala autoaplicada para la depresión de Zung
    • Conde V, Escriba JA, Izquierdo J. Evaluación estadística y adaptación castellana de la escala autoaplicada para la depresión de Zung. Arch Neurobiol. 1970;33:185-206.
    • (1970) Arch Neurobiol , vol.33 , pp. 185-206
    • Conde, V.1    Escriba, J.A.2    Izquierdo, J.3
  • 45
    • 0019844655 scopus 로고
    • Maintenance antidepressant therapy: A double-blind comparison of Trazodone and imipramine
    • Feighner JP. Maintenance antidepressant therapy: a double-blind comparison of Trazodone and imipramine. J Clin Psychopharmacol. 1981;1 Suppl 6:45-8.
    • (1981) J Clin Psychopharmacol , vol.1 , Issue.SUPPL. 6 , pp. 45-48
    • Feighner, J.P.1
  • 46
    • 0023888642 scopus 로고
    • The drug treatment of depression in general practice: A comparison of nocte administration of Trazodone with mianserin, dothiepin and amitriptyline
    • Blacker R. The drug treatment of depression in general practice: a comparison of nocte administration of Trazodone with mianserin, dothiepin and amitriptyline. Psychopharmacology. 1988;95:S18-24.
    • (1988) Psychopharmacology , vol.95
    • Blacker, R.1
  • 47
    • 0023624354 scopus 로고
    • Trazodone versus amitriptyline. A multicentre, double-blind trial in patients hospitalized for depression
    • De Wilde J. Trazodone versus amitriptyline. A multicentre, double-blind trial in patients hospitalized for depression. Acta Therapeutica. 1987;13:439-53.
    • (1987) Acta Therapeutica , vol.13 , pp. 439-453
    • De Wilde, J.1
  • 48
    • 0019855054 scopus 로고
    • Evaluation of Trazodone in the treatment of endogenous depression: Results of a multicenter double-blind study
    • Gershon S. Evaluation of Trazodone in the treatment of endogenous depression: results of a multicenter double-blind study. J Clin Psychopharmacol. 1981;1 Suppl 6:39-44.
    • (1981) J Clin Psychopharmacol , vol.1 , Issue.SUPPL. 6 , pp. 39-44
    • Gershon, S.1
  • 49
    • 0018747289 scopus 로고
    • Trazodone efficacy in depression: A double-blind comparison with imipramine and placebo in day-hospital type patients
    • Fabre LF. Trazodone efficacy in depression: a double-blind comparison with imipramine and placebo in day-hospital type patients. Curr Ther Res. 1979;25:827-34.
    • (1979) Curr Ther Res , vol.25 , pp. 827-834
    • Fabre, L.F.1
  • 50
    • 0024397274 scopus 로고
    • A comparative trial of fluoxetine versus Trazodone in outpatients with major depression
    • Perry PJ. A comparative trial of fluoxetine versus Trazodone in outpatients with major depression. J Clin Psychiatry. 1989;50:290-4.
    • (1989) J Clin Psychiatry , vol.50 , pp. 290-294
    • Perry, P.J.1
  • 51
    • 0025061635 scopus 로고
    • Efficacy and tolerability of controlled-realease Trazodone in depression: A large multicentre study in general practice
    • Moon CAL. Efficacy and tolerability of controlled-realease Trazodone in depression: a large multicentre study in general practice. Curr Med Res Opin. 1990;12:160-8.
    • (1990) Curr Med Res Opin , vol.12 , pp. 160-168
    • Moon, C.A.L.1
  • 52
    • 0019291849 scopus 로고
    • Trazodone in depression
    • Wheatley D. Trazodone in depression. Int Pharmacopsychiatry. 1980;15:240-46.
    • (1980) Int Pharmacopsychiatry , vol.15 , pp. 240-246
    • Wheatley, D.1
  • 53
    • 0021325879 scopus 로고
    • Trazodone: Alternative dose regimens and sleep
    • Wheatley D. Trazodone: alternative dose regimens and sleep. Pharmacotherapeutica. 1983;3:607-12.
    • (1983) Pharmacotherapeutica , vol.3 , pp. 607-612
    • Wheatley, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.