Occurrence of a spinal anaplastic pilocytic astrocytoma and a supratentorial PNET in an adolescent

Journal of Pediatric Hematology/Oncology

Volumn 29, Issue 12, 2007, Pages 832-835

  Blankenburg, Friederike ^a   Van Landeghem, Frank K H ^a   Plotkin, Michail ^a   Henze, Günter ^a   Von Deimling, Andreas ^b   Driever, Pablo Hernáiz ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Anaplastic pilocytic astrocytoma; Supratentorial PNET; TP53; WHO nomenclature

Indexed keywords

CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; IFOSFAMIDE; KI 67 ANTIGEN; METHOTREXATE; TROFOSFAMIDE; VINCRISTINE;

ADOLESCENCE; ADOLESCENT; ARTICLE; ASTROCYTOMA; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER RADIOTHERAPY; CANCER SURGERY; CASE REPORT; DIFFERENTIAL DIAGNOSIS; FEMALE; HISTOPATHOLOGY; HUMAN; NEUROECTODERM TUMOR; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SPINAL ANAPLASTIC PILOCYTIC ASTROCYTOMA;

ADOLESCENT; ASTROCYTOMA; CODON; EXONS; FATAL OUTCOME; FEMALE; HUMANS; MITOTIC INDEX; MUTATION, MISSENSE; NEUROECTODERMAL TUMORS, PRIMITIVE; SPINAL NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 37349113089     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e3181580eb3     Document Type: Article

References (20)

1. Houten JK, Cooper PR. Spinal cord astrocytomas: presentation, management and outcome. J Neurooncol. 2000;47:219-224.
2. Kleihues P, Cavenee WK. Pathology and Genetics of Tumors of the Nervous System. Lyon: IARC Press; 2000.
3. Chen AY, Lee H, Hartman J, et al. Secondary supratentorial primitive neuroectodermal tumor following irradiation in a patient with low-grade astrocytoma. AJNR Am J Neuroradiol. 2005;26:160-162.
4. Hader WJ, Drovini-Zis K, Maguire JA. Primitive neuroectodermal tumors in the central nervous system following cranial irradiation: a report of four cases. Cancer. 2003;97:1072-1076.
5. Neglia JP, Robison LL, Stovall M, et al. New primary neoplasms of the central nervous system in survivors of childhood cancer: a report from the childhood cancer survivor study. J Natl Cancer Inst. 2006;98:1528-1537.
6. Melean G, Sestini R, Ammannati F, et al. Genetic insights into familial tumors of the nervous system. Am J Med Genet C Semin Med Genet. 2004;129:74-84.
7. Lang FF, Miller DC, Pisharody S, et al. High frequency of p53 protein accumulation without p53 gene mutation in human juvenile pilocytic, low grade and anaplastic astrocytomas. Oncogene. 1994;9:949-954.
8. von Deimling A, Fimmers R, Schmidt MC, et al. Comprehensive allelotype and genetic analysis of 466 human nervous system tumors. J Neuropathol Exp Neurol. 2000;59:544-558.
9. Pollack IF, Finkelstein SD, Woods J, et al. Expression of p53 and prognosis in children with malignant gliomas. N Engl J Med. 2002;346:420-427.
10. Adesina AM, Nalbantoglu J, Cavenee WK. P53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma. Cancer Res. 1994;54:5649-5651.
11. Kraus JA, Felsberg J, Tonn JC, et al. Molecular genetic analysis of the tp53, pten, cdkn2a, egfr, cdk4 and mdm2 tumour-associated genes in supratentorial primitive neuroectodermal tumours and glioblastomas of childhood. Neuropathol Appl Neurobiol. 2002;28:325-333.
12. Tweddle DA, Malcolm AJ, Bown N, et al. Evidence for the development of p53 mutations after cytotoxic therapy in a neuroblastoma cell line. Cancer Res. 2001;61:8-13.
13. Tweddle DA, Pearson AD, Haber M, et al. The p53 pathway and its inactivation in neuroblastoma. Cancer Lett. 2003;197:93-98.
14. Kotchetkov R, Driever PH, Cinatl J, et al. Increased malignant behavior in neuroblastoma cells with acquired multi-drug resistance does not depend on p-gp expression. Int J Oncol. 2005;27:1029-1037.
15. Borgwardt L, Hojgaard L, Carstensen H, et al. Increased fluorine-18 2-fluoro-2-deoxy-d-glucose (fdg) uptake in childhood cns tumors is correlated with malignancy grade: a study with fdg positron emission tomography/magnetic resonance imaging coregistration and image fusion. J Clin Oncol. 2005;23:3030-3037.
16. Nadkarni TD, Rekate HL. Pediatric intramedullary spinal cord tumors. Critical review of the literature. Childs Nerv Syst. 1999;15:17-28.
17. Wolff JE, Gnekow AK, Kortmann RD, et al. Preradiation chemotherapy for pediatric patients with high-grade glioma. Cancer. 2002;94:264-271.
18. Peraud A, Herms J, Schlegel J, et al. Recurrent spinal cord astrocytoma with intraventricular seeding. Childs Nerv Syst. 2004;20:114-118.
19. Bowers DC, Gargan L, Kapur P, et al. Study of the mib-1 labeling index as a predictor of tumor progression in pilocytic astrocytomas in children and adolescents. J Clin Oncol. 2003;21:2968-2973.
20. Roessler K, Bertalanffy A, Jezan H, et al. Proliferative activity as measured by mib-1 labeling index and long-term outcome of cerebellar juvenile pilocytic astrocytomas. J Neurooncol. 2002;58:141-146.