A novel optical coherence tomography-based micro-indentation technique for mechanical characterization of hydrogels

Journal of the Royal Society Interface

Volumn 4, Issue 17, 2007, Pages 1169-1173

  Yang, Ying ^a   Bagnaninchi, Pierre O ^a   Ahearne, Mark ^a   Wang, Ruikang K ^b   Liu, Kuo Kang ^a  

^a KEELE UNIVERSITY   (United Kingdom)

^b Oregon Health and Science University Department of Biomedical Engineering   (United States)

Author keywords

Depth sensing; Mechanical properties; Micro indentation; Optical coherence tomography

Indexed keywords

ARTICLE; BIOMECHANICS; CORRELATION ANALYSIS; FORCE; HYDROGEL; IMAGE DISPLAY; IMAGE QUALITY; IMAGE RECONSTRUCTION; INTERMETHOD COMPARISON; MATERIALS TESTING; MOLECULAR MECHANICS; OPTICAL COHERENCE TOMOGRAPHY; QUANTITATIVE ANALYSIS; THEORETICAL STUDY; YOUNG MODULUS;

EID: 37349100832     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2007.1044     Document Type: Article

References (18)

1. Ahearne, M., Yang, Y., El Haj, A. J., Then, K. Y. & Liu, K. K. 2005 Characterizing the viscoelastic properties of thin hydrogel-based constructs for tissue engineering applications. J. R. Soc. Interface 2, 455-463. (doi:10.1098/rsif.2005.0065)
2. Anseth, K. S., Bowman, C. N. & Brannon-Peppas, L. 1996 Mechanical properties of hydrogels and their experimental determination. Biomaterials 17, 1647-1657. (doi:10.1016/0142-9612(96)87644-7)
3. Briscoe, B. J., Fiori, L. & Pelillo, E. 1998 Nano-indentation of polymeric surfaces. J. Phys. D: Appl. Phys. 31, 2395-2405. (doi:10.1088/0022-3727/31/19/006)
4. Chen, Q., Ringleb, S. I., Hulshizer, T. & An, K. N. 2005 Identification of the testing parameters in high frequency dynamic shear measurement on agarose gels. J. Biomech. 38, 959-963. (doi:10.1016/j.jbiomech.2004.05.015)
5. Fung, Y. C. 1993 Biomechanics: mechanical properties of living tissues, 2nd edn. New York, NY: Springer.
6. Hertz, H. Z. 1882 On the contact of elastic solids. J. Reine Angew. Math. 92, 156-171.
7. Johnson, K. L. 1985 Contact mechanics. Cambridge, UK: Cambridge University Press.
8. Khail, A. S., Chan, R. C., Chau, A. H., Bouma, B. E. & Mofrad, M. K. 2005 Tissue elasticity estimation with optical coherence elastography: toward mechanical characterization of in vivo tissue. Ann. Biomed. Eng. 33, 1631-1639. (doi:10.1007/s10439-005-6766-3)
9. Khoo, H. S., Liu, K. K. & Tseng, F. G. 2003 Mechanical strength and interfacial failure analysis of cantilevered SU-8 microposts. J. Micromech. Microeng. 13, 822-831. (doi:10.1088/0960-1317/13/6/305)
10. Nishizawa, N., Chen, Y., Hsiung, P., Ippen, E. P. & Fujimoto, J. G. 2004 Real-time, ultrahigh-resolution, optical coherence tomography with an all-fiber, femtosecond fiber laser continuum at 1.5 μm. Opt. Lett. 29, 2846-2848. (doi:10.1364/OL.29.002846)
11. Pierard, G. E. & Lapiere, C. M. 1997 Physiopathological variations in the mechanical properties of skin. Arch. Dermatol. Res. 260, 231-239.
12. Purslow, P. P. 2002 The structure and functional significance of variations in the connective tissue within muscle. Comp. Biochem. Physiol. A 133, 947-966. (doi:10.1016/S1095-6433(02)00141-1)
13. Schmitt, J. M. 1998 OCT elastography: imaging microscopic deformation and strain of tissue. Opt. Express 3, 199-211.
14. Tuchin, V. V. 2000 Tissue optics: light scattering methods and instruments for medical diagnosis. Bellingham, WA: SPIE Press Ltd.
15. Wang, R. K., Xu, X. Q., Tuchin, V. V. & Elder, J. B. 2001 Concurrent enhancement of imaging depth and contrast for optical coherence tomography by hyperosmotic agents. J. Opt. Soc. Am. B 18, 948-953.
16. Wang, R. K., Ma, Z. & Kirkpatrick, S. J. 2006 Tissue Doppler optical coherence elastography for real time strain rate and strain mapping of soft tissue. Appl. Phys. Lett. 89, 144 103. (doi:10.1063/1.2357854)
17. Wells, S. M., Langille, B. L., Lee, J. M. & Adamson, S. L. 1999 Determinants of mechanical properties in the developing ovine thoracic aorta. Am. J. Physiol. Heart Circ. Physiol. 277, H1385-H1391.
18. Yang, Y., Dubois, A., Qin, X., Li, J., El Haj, A. & Wang, R. K. 2006 Investigation of optical coherence tomography as an imaging modality in tissue engineering. Phys. Med. Biol. 51, 1649-1659. (doi:10.1088/0031- 9155/51/7/001)