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Volumn 7, Issue 12, 2007, Pages 1737-1747

Biomarkers in clear cell renal cell carcinoma

Author keywords

Antiangiogenic therapy; Biomarker; Clear cell renal cell carcinoma; Genetic markers; Molecular markers; Predicting response; Targeted therapy; VHL mutation

Indexed keywords

ALPHA INTERFERON; AXITINIB; BEVACIZUMAB; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CALCIUM; CARBONATE DEHYDRATASE IX; GLUCOSE TRANSPORTER 1; HEMOGLOBIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; INTERLEUKIN 2; INTERLEUKIN 6; LACTATE DEHYDROGENASE; PLACEBO; PROTEIN P53; PROTEIN TYROSINE KINASE INHIBITOR; SORAFENIB; SUNITINIB; TEMSIROLIMUS; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HIF; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR; VON HIPPEL LINDAU PROTEIN;

EID: 37349094385     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/14737140.7.12.1737     Document Type: Review
Times cited : (17)

References (38)
  • 2
    • 0042342564 scopus 로고    scopus 로고
    • The von Hippel-Lindau protein, vascular endothelial growth factor, and kidney cancer
    • George DJ, Kaelin WG Jr. The von Hippel-Lindau protein, vascular endothelial growth factor, and kidney cancer. N. Engl. J. Med. 349, 419-421 (2003).
    • (2003) N. Engl. J. Med , vol.349 , pp. 419-421
    • George, D.J.1    Kaelin Jr., W.G.2
  • 3
    • 33846876103 scopus 로고    scopus 로고
    • Identification of the genes for kidney cancer: Opportunity for disease-specific targeted therapeutics
    • Linehan WM, Pinto PA, Srinivasan R et al. Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics. Clin. Cancer Res., 13, S671-S679(2007).
    • (2007) Clin. Cancer Res , vol.13
    • Linehan, W.M.1    Pinto, P.A.2    Srinivasan, R.3
  • 4
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst. 92, 205-216 (2000).
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 5
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon α, or both for advanced renal-cell carcinoma
    • Hudes G, Carducci M, Tomczak P et al. Temsirolimus, interferon α, or both for advanced renal-cell carcinoma. N Engl. J. Med. 356, 2271-2281 (2007).
    • (2007) N Engl. J. Med , vol.356 , pp. 2271-2281
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3
  • 6
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon α in metastatic renal-cell carcinoma
    • Motzer RJ, Hutson TE, Tomczak P et al. Sunitinib versus interferon α in metastatic renal-cell carcinoma. N. EngL J Med. 356, 115-124 (2007).
    • (2007) N. EngL J Med , vol.356 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 7
    • 33846148701 scopus 로고    scopus 로고
    • Sorafenib in advanced clear-cell renal-cell carcinoma
    • Escudier B, Eisen T, Stadler WM et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N. Engl. J. Med. 356, 125-134 (2007).
    • (2007) N. Engl. J. Med , vol.356 , pp. 125-134
    • Escudier, B.1    Eisen, T.2    Stadler, W.M.3
  • 8
    • 37349047409 scopus 로고    scopus 로고
    • Figlin R. Prognostic factors and biomarkers for renal cell carcinoma surrogate markers. Presented at: 4th International Congress on Kidney and Bladder Cancer. Orlando, FL, USA, 27-31 March 2007.
    • Figlin R. Prognostic factors and biomarkers for renal cell carcinoma "surrogate markers". Presented at: 4th International Congress on Kidney and Bladder Cancer. Orlando, FL, USA, 27-31 March 2007.
  • 9
    • 3543131382 scopus 로고    scopus 로고
    • A naturally occurring soluble form of vascular endothelial growth factor receptor 2 detected in mouse and human plasma
    • Ebos JM, Bocci G, Man S et al. A naturally occurring soluble form of vascular endothelial growth factor receptor 2 detected in mouse and human plasma. Mol. Cancer Res. 2, 315-326 (2004).
    • (2004) Mol. Cancer Res , vol.2 , pp. 315-326
    • Ebos, J.M.1    Bocci, G.2    Man, S.3
  • 10
    • 0032772880 scopus 로고    scopus 로고
    • Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
    • Motzer RJ, Mazumdar M, Bacik J et al. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J. Clin. Oncol. 17, 2530-2540 (1999).
    • (1999) J. Clin. Oncol , vol.17 , pp. 2530-2540
    • Motzer, R.J.1    Mazumdar, M.2    Bacik, J.3
  • 11
    • 14144252047 scopus 로고    scopus 로고
    • Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma
    • Mekhail TM, Abou-Jawde RM, Boumerhi G et al. Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma. J. Clin. Oncol. 23, 832-841 (2005).
    • (2005) J. Clin. Oncol , vol.23 , pp. 832-841
    • Mekhail, T.M.1    Abou-Jawde, R.M.2    Boumerhi, G.3
  • 12
    • 34547108341 scopus 로고    scopus 로고
    • Clinical factors associated with outcome in patients with metastatic clear-cell renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy
    • Choueiri TK, Garcia JA, Elson P et al. Clinical factors associated with outcome in patients with metastatic clear-cell renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. Cancer 110, 543-550(2007).
    • (2007) Cancer , vol.110 , pp. 543-550
    • Choueiri, T.K.1    Garcia, J.A.2    Elson, P.3
  • 13
    • 2142853538 scopus 로고    scopus 로고
    • Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma
    • Beck SD, Patel MI, Snyder ME et al. Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma. Ann. Surg. Oncol. 11, 71-77 (2004).
    • (2004) Ann. Surg. Oncol , vol.11 , pp. 71-77
    • Beck, S.D.1    Patel, M.I.2    Snyder, M.E.3
  • 14
    • 0036569472 scopus 로고    scopus 로고
    • Treatment outcome and survival associated with metastatic renal cell carcinoma of non-clear-cell histology
    • Motzer RJ, Bacik J, Mariani T et al. Treatment outcome and survival associated with metastatic renal cell carcinoma of non-clear-cell histology. J. Clin. Oncol. 20, 2376-2381(2002).
    • (2002) J. Clin. Oncol , vol.20 , pp. 2376-2381
    • Motzer, R.J.1    Bacik, J.2    Mariani, T.3
  • 15
    • 0036160550 scopus 로고    scopus 로고
    • Allelic loss on chromosomes 8 and 9 correlates with clinical outcome in locally advanced clear cell carcinoma of the kidney
    • Presti JC Jr, Wilhelm M, Reuter V et al. Allelic loss on chromosomes 8 and 9 correlates with clinical outcome in locally advanced clear cell carcinoma of the kidney. J Urol. 167, 1464-1468 (2002).
    • (2002) J Urol , vol.167 , pp. 1464-1468
    • Presti Jr, J.C.1    Wilhelm, M.2    Reuter, V.3
  • 16
    • 37349014042 scopus 로고    scopus 로고
    • Future directions in targeted therapy for renal carcinoma. Extended education session; biology and targeted therapy for advanced renal cell carcinoma
    • Presented at:, Chicago, IL, USA, June 1-5
    • Bukowski RM. Future directions in targeted therapy for renal carcinoma. Extended education session; biology and targeted therapy for advanced renal cell carcinoma. Presented at: American Society of Clinical Oncology, 2007 ASCO Annual Meeting. Chicago, IL, USA, June 1-5 2007.
    • (2007) American Society of Clinical Oncology, 2007 ASCO Annual Meeting
    • Bukowski, R.M.1
  • 17
    • 34547779489 scopus 로고    scopus 로고
    • Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: Modulation of VEGF and VEGF-related proteins
    • Deprimo SE, Bello CL, Smeraglia J et al Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins. J. Transl. Med. 5, 32(2007).
    • (2007) J. Transl. Med , vol.5 , pp. 32
    • Deprimo, S.E.1    Bello, C.L.2    Smeraglia, J.3
  • 18
    • 33644833910 scopus 로고    scopus 로고
    • Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
    • Motzer RJ, Michaelson MD, Redman BG et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J. Clin. Oncot 24, 16-24 (2006).
    • (2006) J. Clin. Oncot , vol.24 , pp. 16-24
    • Motzer, R.J.1    Michaelson, M.D.2    Redman, B.G.3
  • 19
    • 2942756034 scopus 로고    scopus 로고
    • Interleukin-6, interleukin- 10, and vascular endothelial growth factor in metastatic renal cell carcinoma: Prognostic value of interleukin-6 - from the Groupe Francais d'Immunotherapie
    • Negrier S, Perol D, Menetrier-Caux C et al. Interleukin-6, interleukin- 10, and vascular endothelial growth factor in metastatic renal cell carcinoma: prognostic value of interleukin-6 - from the Groupe Francais d'Immunotherapie. J. Clin. Oncol. 22, 2371-2378(2004).
    • (2004) J. Clin. Oncol , vol.22 , pp. 2371-2378
    • Negrier, S.1    Perol, D.2    Menetrier-Caux, C.3
  • 20
    • 39149121748 scopus 로고    scopus 로고
    • Serum level of vascular endothelial growth factor (VEGF) as an independent prognostic factor in metastatic renal cell carcinoma (MRCC)
    • Abstract 5044
    • Negrier S, Chabaud S, Escudier B et al. Serum level of vascular endothelial growth factor (VEGF) as an independent prognostic factor in metastatic renal cell carcinoma (MRCC). J. Clin. Oncol. 25, S18 (2007) (Abstract 5044).
    • (2007) J. Clin. Oncol , vol.25
    • Negrier, S.1    Chabaud, S.2    Escudier, B.3
  • 21
    • 33847042328 scopus 로고    scopus 로고
    • Detection of transcript for brain-type fatty acid-binding protein in tumor and urine of patients with renal cell carcinoma
    • Teratani T, Domoto T, Kuriki K et al. Detection of transcript for brain-type fatty acid-binding protein in tumor and urine of patients with renal cell carcinoma. Urology 69, 236-240 (2007).
    • (2007) Urology , vol.69 , pp. 236-240
    • Teratani, T.1    Domoto, T.2    Kuriki, K.3
  • 22
    • 0346059548 scopus 로고    scopus 로고
    • Promoter hypermethylation of tumor suppressor genes in urine from kidney cancer patients
    • Battagli C, Uzzo RG, Dulaimi E et al. Promoter hypermethylation of tumor suppressor genes in urine from kidney cancer patients. Cancer Res. 63, 8695-8699 (2003).
    • (2003) Cancer Res , vol.63 , pp. 8695-8699
    • Battagli, C.1    Uzzo, R.G.2    Dulaimi, E.3
  • 23
    • 33947198698 scopus 로고    scopus 로고
    • Immunohistochemical expression of hypoxia inducible factor-1α and its downstream molecules in sarcomatoid renal cell carcinoma
    • Tickoo SK, Alden D, Olgac S et al. Immunohistochemical expression of hypoxia inducible factor-1α and its downstream molecules in sarcomatoid renal cell carcinoma. J. Urol. 177, 1258-1263 (2007).
    • (2007) J. Urol , vol.177 , pp. 1258-1263
    • Tickoo, S.K.1    Alden, D.2    Olgac, S.3
  • 24
    • 12944266844 scopus 로고    scopus 로고
    • The expression of hypoxia-inducible factor- 1 α is a favorable independent prognostic factor in renal cell carcinoma
    • Lidgren A, Hedberg Y, Grankvist K et al. The expression of hypoxia-inducible factor- 1 α is a favorable independent prognostic factor in renal cell carcinoma. Clin. Cancer Res. 11, 1129-1135 (2005).
    • (2005) Clin. Cancer Res , vol.11 , pp. 1129-1135
    • Lidgren, A.1    Hedberg, Y.2    Grankvist, K.3
  • 25
    • 31844442511 scopus 로고    scopus 로고
    • Perturbations in hypoxia detection: A shared fink between hereditary and sporadic tumor formation?
    • Sharifi N, Farrar WL. Perturbations in hypoxia detection: a shared fink between hereditary and sporadic tumor formation? Med. Hypotheses 66, 732-735 (2006).
    • (2006) Med. Hypotheses , vol.66 , pp. 732-735
    • Sharifi, N.1    Farrar, W.L.2
  • 26
    • 16844370348 scopus 로고    scopus 로고
    • G250: A carbonic anhydrase IX monoclonal antibody
    • Lam JS, Pantuck AJ, Belldegrun AS et al. G250: a carbonic anhydrase IX monoclonal antibody. Curr. Oncol. Rep. 7, 109-115 (2005).
    • (2005) Curr. Oncol. Rep , vol.7 , pp. 109-115
    • Lam, J.S.1    Pantuck, A.J.2    Belldegrun, A.S.3
  • 27
    • 2442490125 scopus 로고    scopus 로고
    • Prognostic value of carbonic anhydrase IX and K167 as predictors of survival for renal clear cell carcinoma
    • Bui MH, Visapaa H, Seligson D et al. Prognostic value of carbonic anhydrase IX and K167 as predictors of survival for renal clear cell carcinoma. J. Urol. 171, 2461-2466 (2004).
    • (2004) J. Urol , vol.171 , pp. 2461-2466
    • Bui, M.H.1    Visapaa, H.2    Seligson, D.3
  • 28
    • 21044442672 scopus 로고    scopus 로고
    • Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer
    • Atkins M, Regan M, McDermott D et al. Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer. Clin. Cancer Res., 11, 3714-3721 (2005).
    • (2005) Clin. Cancer Res , vol.11 , pp. 3714-3721
    • Atkins, M.1    Regan, M.2    McDermott, D.3
  • 29
    • 18844386435 scopus 로고    scopus 로고
    • Histologic predictors of renal cell carcinoma response to interleukin-2-based therapy
    • 2005
    • Upton MR Parker RA, Youmans A et al. Histologic predictors of renal cell carcinoma response to interleukin-2-based therapy. J. Immunother. (1997) 28, 488-495 (2005).
    • (1997) J. Immunother , vol.28 , pp. 488-495
    • Upton, M.R.1    Parker, R.A.2    Youmans, A.3
  • 30
    • 34249821948 scopus 로고    scopus 로고
    • CA9 gene expression in conventional renal cell carcinoma: A potential marker for prediction of early metastasis after nephrectomy
    • Li G, Feng G, Gentil-Perret A et al. CA9 gene expression in conventional renal cell carcinoma: a potential marker for prediction of early metastasis after nephrectomy. Clin. Exp. Metastasis 24, 149-155 (2007).
    • (2007) Clin. Exp. Metastasis , vol.24 , pp. 149-155
    • Li, G.1    Feng, G.2    Gentil-Perret, A.3
  • 31
    • 44549084875 scopus 로고    scopus 로고
    • Use of Von-Hippel-Lindau (VHL) mutation status to predict objective response to vascular endothelial growth factor (VEGF)-targeted therapy in metastatic renal cell carcinoma (RCC)
    • Abstract 5012
    • Choueiri TK, Vaziri S, Rini BI et al. Use of Von-Hippel-Lindau (VHL) mutation status to predict objective response to vascular endothelial growth factor (VEGF)-targeted therapy in metastatic renal cell carcinoma (RCC). J Clin. Oncol. 25, S18 (2007) (Abstract 5012).
    • (2007) J Clin. Oncol , vol.25
    • Choueiri, T.K.1    Vaziri, S.2    Rini, B.I.3
  • 32
    • 0037120977 scopus 로고    scopus 로고
    • VHL tumor suppressor gene alterations associated with good prognosis in sporadic clear-cell renal carcinoma
    • Yao M, Yoshida M, Kishida T et al. VHL tumor suppressor gene alterations associated with good prognosis in sporadic clear-cell renal carcinoma. J. Natl Cancer Inst. 94, 1569-1575 (2002).
    • (2002) J. Natl Cancer Inst , vol.94 , pp. 1569-1575
    • Yao, M.1    Yoshida, M.2    Kishida, T.3
  • 33
    • 20444425310 scopus 로고    scopus 로고
    • Allelic loss of 3p25 associated with alterations of 5q22.3 approximately q23.2 may affect the prognosis of conventional renal cell carcinoma
    • Nagao K, Yamaguchi S, Matsuyama H et al. Allelic loss of 3p25 associated with alterations of 5q22.3 approximately q23.2 may affect the prognosis of conventional renal cell carcinoma. Cancer Genet. Cytogenet. 160,43-48 (2005).
    • (2005) Cancer Genet. Cytogenet , vol.160 , pp. 43-48
    • Nagao, K.1    Yamaguchi, S.2    Matsuyama, H.3
  • 34
    • 33644818141 scopus 로고    scopus 로고
    • Detection of circulating tumor cells from renal carcinoma patients: Experiences of a two-center study
    • Blumke K, Bilkenroth U, Schmidt U et al. Detection of circulating tumor cells from renal carcinoma patients: experiences of a two-center study. Oncol Rep. 14, 895-899 (2005)..
    • (2005) Oncol Rep , vol.14 , pp. 895-899
    • Blumke, K.1    Bilkenroth, U.2    Schmidt, U.3
  • 35
    • 33845313947 scopus 로고    scopus 로고
    • p21 is a prognostic marker for renal cell carcinoma: Implications for novel therapeutic approaches
    • discussion 68-69
    • Weiss RH, Borowsky AD, Seligson D et al. p21 is a prognostic marker for renal cell carcinoma: implications for novel therapeutic approaches. J. Urol. 177, 63-68; discussion 68-69 (2007).
    • (2007) J. Urol , vol.177 , pp. 63-68
    • Weiss, R.H.1    Borowsky, A.D.2    Seligson, D.3
  • 36
    • 34250209885 scopus 로고    scopus 로고
    • Survivin and b7-h1 are collaborative predictors of survival and represent potential therapeutic targets for patients with renal cell carcinoma
    • Krambeck AE, Dong H, Thompson RH et al. Survivin and b7-h1 are collaborative predictors of survival and represent potential therapeutic targets for patients with renal cell carcinoma. Clin. Cancer Pes. 13,1749-1756(2007).
    • (2007) Clin. Cancer Pes , vol.13 , pp. 1749-1756
    • Krambeck, A.E.1    Dong, H.2    Thompson, R.H.3
  • 37
    • 0030796001 scopus 로고    scopus 로고
    • Role of interleukin-6 in the paraneoplastic inflammatory syndrome associated with renal-cell carcinoma
    • Blay JY, Rossi JF, Wijdenes J et al. Role of interleukin-6 in the paraneoplastic inflammatory syndrome associated with renal-cell carcinoma. Int. J. Cancer 72, 424-430 (1997).
    • (1997) Int. J. Cancer , vol.72 , pp. 424-430
    • Blay, J.Y.1    Rossi, J.F.2    Wijdenes, J.3
  • 38
    • 33744829237 scopus 로고    scopus 로고
    • CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/HIF-1α/VEGF signaling
    • Wan X, Shen N, Mendoza A et al. CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/HIF-1α/VEGF signaling. Neoplasia 8, 394-401 (2006).
    • (2006) Neoplasia , vol.8 , pp. 394-401
    • Wan, X.1    Shen, N.2    Mendoza, A.3


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