Relationship between the results of in vitro receptor binding assay to human estrogen receptor α and in vivo uterotrophic assay: Comparative study with 65 selected chemicals

Toxicology in Vitro

Volumn 22, Issue 1, 2008, Pages 225-231

  Akahori, Yumi ^a,b   Nakai, Makoto ^b   Yamasaki, Kanji ^c   Takatsuki, Mineo ^b   Shimohigashi, Yasuyuki ^d   Ohtaki, Masahiro ^a  

^a OCHANOMIZU UNIVERSITY   (Japan)

^b Chemicals Evaluation and Research Institute   (Japan)

^c CHEMICALS EVALUATION AND RESEARCH INSTITUTE   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

Binding assay; Concordance; Uterotrophic assay

Indexed keywords

ENDOCRINE DISRUPTOR; ESTROGEN RECEPTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; RECEPTOR BINDING; UTEROTROPHIC ASSAY;

ANIMALS; BIOLOGICAL ASSAY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR MODULATORS; ESTROGENS; FEMALE; HUMANS; PROTEIN BINDING; RATS; UTERUS;

EID: 37349075026     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.08.004     Document Type: Article

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