Lymphoproliferative response and its relationship with histological lesions in experimental ovine paratuberculosis and its diagnostic implications

Veterinary Research Communications

Volumn 32, Issue 1, 2008, Pages 107-119

  Kurade, N P ^a   Tripathi, B N ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Cellular immune response; Lymphocyte Stimulation Test; Lymphoproliferative response; Mycobacterium avium paratuberculosis; Ovine; Paratuberculosis; Sheep

Indexed keywords

CONCANAVALIN A; TETRAZOLIUM; TUBERCULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; CELLULAR IMMUNITY; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE DURATION; FECES ANALYSIS; FEMALE; HISTOPATHOLOGY; IN VITRO STUDY; LYMPHOCYTE TRANSFORMATION TEST; MALE; MYCOBACTERIUM PARATUBERCULOSIS; NONHUMAN; PARATUBERCULOSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; SHEEP;

ANIMALS; FECES; FEMALE; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; PARATUBERCULOSIS; SHEEP; SHEEP DISEASES; TIME FACTORS;

ANIMALIA; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS; OVIS; OVIS ARIES;

EID: 37349069358     PISSN: 01657380     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11259-007-9008-8     Document Type: Article

References (34)

1. Anderson, P., Askgaard, D., Ljungqvist, L., Bentzon, M.W. and Heron, I., 1991. T-cell proliferative response to antigens secreted by Mycobacterium tuberculosis. Infection Immunity, 59, 1558-1563
2. Angus, K.W., 1990. Intestinal lesions resembling paratuberculosis in a wild rabbit (Oryctolagus cuniculus). Journal of Comparative Pathology, 103, 101-105
3. Begara McGorum, I., Wildblood, L.A., Clarke, C.J., Connor, K.M., Stevenson, K., Mclnnes, C.J., Sharp, J.M. and Jones, D.G., 1998. Early immunopathological events in experimental ovine paratuberculosis. Veterinary Immunology Immunopathology, 63, 265-287
4. Bloom, B.R., 1986. Learning from leprosy: A perspective on immunology and the third world. Journal of Immunology, 137, 1-10
5. Brett, S.J. and Ivanyi, J., 1990. Genetic influence on the immune repertoire following tuberculous infection in mice. Immunology, 71, 113-119
6. Brownback, P.E. and Barrow, W.W., 1988. Modified lymphocyte response to nitrogen after intraperitoneal injection of glycopeptide lipid antigen from Mycobacterium avium complex. Infection Immunity, 56, 1044-1050
7. Burrells, C., Clarke, C.J., Colston, A., Kay, J.M., Porter, J., Little, D. and Sharp, J.M., 1998. A study of immunological responses of sheep clinically-affected with paratuberculosis (Johne's disease). The relationship of blood, mesenteric lymph node and intestinal lymphocyte responses to gross and microscopic pathology. Veterinary Immunology Immunopathology, 66, 343-358
8. Burrells, C., Clarke, C.J., Colston A., Kay J.M., Porter J., Little, D. and Sharp, J.M., 1999. Interferon- gamma and interleucin-2 release by lymphocytes derived form the blood, mesenteric lymph nodes and intestines of normal sheep and those affected with paratuberculosis. (Johne's disease). Veterinary Immunology Immunopathology, 68, 139-148
9. Chiodini, R.J., Van Kruiningen, H.J. and Merkal, R.S., 1984. Ruminant paratuberculosis (Johne's disease): The current status and future prospects. Cornell Veterinarian, 74, 218-262
10. Clarke, C.J., 1997. The pathology and pathogenesis of paratuberculosis in ruminants and other species. Journal of Comparative Pathology, 116, 217-261
11. Closs, O., Lovik, M., Wigzell H. and Taylor, B.A., 1983. H-2 linked gene(s) influence the granulomatous reaction to viable Mycobacterum lepraemurium in the mouse. Scandinavian Journal of Immunology, 18, 59
12. Denis, M., Forget, A., Pelletier, M. Turcotte, R. and Skamene, E., 1986. Control of Bcg gene of early resistance in mice to infections with BCG substrains and atypical mycobacteria. Clinical Experimental Immunology, 63, 517-525
13. Fifis, T., Corner, L.A., Rothel, J.S. and Wood, P.R., 1994. Cellular and humoral immune responses of cattle to Mycobacterium bovis antigens. Scandinavian Journal of Immunology, 39, 267-274
14. Fournie, J.J., Adams, E., Mullins, R.J. and Basten, A., 1989. Inhibition of human lymphoproliferative responses by mycobacterial phenolic glycolipids. Infection Immunity, 57, 3653-3659
15. Greig, A., Stevenson, K., Perez, V., Pirie, A.A., Grant, J.M., and Sharp J.M., 1997. Paratuberculosis in wild rabbits (Oryctolagus cuniculus). Veterinary Record, 140, 141-143
16. Harboe, M., Andersen, P., Colston, J.M., Gicquel, B., Hermans, P.W.M., Ivanyl, J. and Kautmann, S.H.E., 1996. Vaccine against tuberculosis. Vaccine, 14, 710-776
17. Ivanyi, J., Bothamley, G.H. and Jackett, P.S., 1988. Immuno-diagnostic assays for tuberculosis and leprosy. British Medical Bulletin, 44, 635-649
18. Kreeger, J.M., 1991. Ruminant paratuberculosis - a century of progress and frustration. Journal of Veterinary Diagnostic Investigations, 3, 373-383
19. Kurade, N.P., Tripathi, B.N., Rajukumar, K. and Parihar N.S., 2004. Sequential development of histologic lesions and their relationship with bacterial isolation, fecal shedding, and immune responses during progressive stages of experimental infection of lambs with Mycobacterium avium subspecies paratuberculosis. Veterinary Pathology 41, 378-387
20. Lepper, A.W.D., Wilks, C.R., Kotiwi, M., Whitehead, J.T. and Swart, K.S., 1989. Sequential bacteriological observations in relation to cell mediated and humoral antibody responses of cattle infected with Mycobacterium paratuberculosis and maintained on normal or high iron intake. Australian Veterinary Journal, 66, 50-55
21. Little, D., Alzuherri, H.M. and Clarke, C.J., 1996. Phenotypic characterisation of intestinal lymphocytes in ovine paratuberculosis by immunohistochemistry. Veterinary Immunology Immunopathology, 55, 175-187
22. Mehra,V., Mason, L.H., Fields, J.P. and Bloom, B.R., 1979. Lepromin-induced suppressor cells in patients with leprosy. Journal of Immunology, 123, 1813-1817
23. Mosmann, T., 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxic assay. Journal of Immunological Methods, 65, 55-63
24. Orme, I.M., Furney, S.K. and Roberts A.D., 1992. Dissemination of Mycobacterium avium infection in mice redered immunodeficient by thymectomy and CD4 depletion or by prior infection with murine AIDS retroviruses. Infection Immunity, 60, 4747-4753
25. Perez, V., Garcia-Marin, J.F. and Badiola, J.J., 1996. Description and classification of different grades of lesions associated with natural paratuberculosis infection in sheep. Journal of Comparative Pathology, 114, 107-122
26. Perez, V., Tellechea, J., Corpa, J.M., Gutierrez, M. and Garcia-Marin, J.F., 1999. Relation between pathologic findings and cellular immune responses in sheep with naturally acquired paratuberculosis. American Journal of Veterinary Research, 60, 123-127
27. Rajukumar, K., Tripathi, B.N., Kurade, N.P. and Parihar N.S., 2001. An enzyme-linked immunosorbent assay using immunoaffinity-purified antigen in the diagnosis of caprine paratuberculosis and its comparison with conventional ELISA's. Veterinary Research Communication, 25, 539-553
28. Sibley, L.D., Hunter, S.W., Brennan, P.J. and Krahenbuhl, J.L., 1988. Mycobacterial lipoarabinomannan inhibits gamma interferon-mediated activation of macrophages. Infection Immunity, 56, 1232-1236
29. Sibley, L.D., Adams, L.B., and Krahenbuhl, J.L., 1990. Inhibition of interferon mediated activation in mouse macrophages treated with lipoarbinomannan. Clinical and Experimental Immunology, 80, 141-148
30. Snedecor, G.W. and Cochran, W.G., 1989. Statistical methods, 8th edn, (Oxford and IBH Publishing Co.,New Delhi, India)
31. Stabel, J.R., 2000. Transitions in immune responses to Mycobacterium paratuberculosis. Veterinary Microbiology, 77, 465-473
32. Tripathi, B.N., Munjal, S.K. and Paliwal, O.P., 2002. An overview of paratuberculosis (Johne's disease) in animals. Indian Journal of Veterinary Pathology, 26, 1-10
33. Wells, P.W., Burrells, C. and Martin, W.B., 1977. Reduced mitogenic response of lymphocytes from newly-calved cows. Clinical and Experimental Immunology, 29, 159-161
34. Yamamura, M., Uyemura, K., Deans, R.J., Weinberg, K., Rea, T.H., Bloom, B.R. and Modlin, R.L., 1991. Defining protective responses to pathogens: cytokine profiles in leprosy. Science, 254, 277-279