Trichinella spiralis: Characterization of phage-displayed specific epitopes and their protective immunity in BALB/c mice

Experimental Parasitology

Volumn 118, Issue 1, 2008, Pages 66-74

  Gu, Yuan ^a   Li, Jie ^b   Zhu, Xinping ^a   Yang, Jing ^a   Li, Qiang ^a   Liu, Zhiying ^a   Yu, Shun ^c   Li, Yaohua ^c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Beijing Centers for Diseases Control and Prevention   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

BALB c mice; Bio panning; Characterization; DAB; deoxyribonucleic acid; diaminobenzidine; DNA; ECL; ELISA; enhanced chemiluminescence; enzyme linked immunosorbent assay; Epitope; ES; excretory secretory; FITC; fluorescein isothiocyanate; horseradish peroxidase; HRP; mAb; major histocompatibility complex; MHC; Mimotope; molecular mass; monoclonal antibody; MW; Nematode; NGS; normal goat serum; OD; optical density; PBS; PBS T; Phage display; phosphate buffered saline; phosphate buffered saline Tween; Protective immunity; recombinant Ts87 protein; rTs87; SDS PAGE; sodium dodecyl sulphate polyacrylamide gel electrophoresis; TBS T; Trichinella spiralis; Trichinellosis; Tris buffered saline Tween

Indexed keywords

ADJUVANT; EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 5A3; PEPTIDE LIBRARY; RECOMBINANT TS87 PROTEIN; RECOMBINANT VACCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; MOLECULAR CLONING; MOUSE; MULTIPLE CYCLE TREATMENT; NEMATODIASIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE IMMUNITY; PHAGE DISPLAY; PRIORITY JOURNAL; TRICHINELLA SPIRALIS; VACCINATION; WORM INFECTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, HELMINTH; ANTIBODIES, MONOCLONAL; ANTIGENS, HELMINTH; BACTERIOPHAGES; BASE SEQUENCE; BLOTTING, WESTERN; CLONING, MOLECULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FEMALE; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; SPECIFIC PATHOGEN-FREE ORGANISMS; TRICHINELLA SPIRALIS; TRICHINOSIS; VACCINES;

ARMORACIA RUSTICANA; CAPRA HIRCUS; MUS; PROKARYOTA; TRICHINELLA SPIRALIS;

EID: 37349066503     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2007.06.014     Document Type: Article

References (34)

1. Andre S., Arnusch C.J., Kuwabara I., Russwurm R., Kaltner H., Gabius H.J., and Pieters R.J. Identification of peptide ligands for malignancy- and growth-regulating galectins using random phage-display and designed combinatorial peptide libraries. Bioorganic & Medicinal Chemistry 13 (2005) 563-573
2. Bastien N., Trudel M., and Simard C. Protective immune responses induced by the immunization of mice with a recombinant bacteriophage displaying an epitope of the human Respiratory Syncytial Virus. Virology 234 (1997) 118-122
3. Benhar I. Biotechnological applications of phage and cell display. Biotechnology Advances 19 (2001) 1-33
4. Buchwald U.K., Lees A., Steinitz M., and Pirofski L.A. A peptide mimotope of type 8 pneumococcal capsular polysaccharide induces a protective immune response in mice. Infection and Immunity 73 (2005) 325-333
5. Cardellini E., Felici F., and Gianfranceschi G.L. Identification of peptides mimicking the ligands of proteins phosphorylated by protein kinase CK2. Peptides 25 (2004) 191-197
6. Casey J.L., Coley A.M., Anders R.F., Murphy V.J., Humberstone K.S., Thomas A.W., and Foley M. Antibodies to malaria peptide mimics inhibit Plasmodium falciparum invasion of erythrocytes. Infection and Immunity 72 (2004) 1126-1134
7. Dea-Ayuela M.A., Rama-Iniguez S., and Bolas-Fernandez F. Vaccination of mice against intestinal Trichinella spiralis infections by oral administration of antigens microencapsulated in methacrilic acid copolymers. Vaccine 24 (2006) 2772-2780
8. de la Cruz V.F., Lal A.A., and McCutchan T.F. Immunogenicity and epitope mapping of foreign sequences via genetically engineered filamentous phage. The Journal of Biological Chemistry 263 (1988) 4318-4322
9. Deville S., Pooter A., Aucouturier J., Laine-Prade V., Cote M., Boireau P., and Vallee I. Influence of adjuvant formulation on the induced protection of mice immunized with total soluble antigen of Trichinella spiralis. Veterinary Parasitology 132 (2005) 75-80
10. Dromey J.A., Weenink S.M., Peters G.H., Endl J., Tighe P.J., Todd I., and Christie M.R. Mapping of epitopes for autoantibodies to the type 1 diabetes autoantigen IA-2 by peptide phage display and molecular modeling: overlap of antibody and T cell determinants. Journal of Immunology 172 (2004) 4084-4090
11. Gamble H.R., and Graham C.E. Monoclonal antibody-purified antigen for the immunodiagnosis of trichinosis. American Journal of Veterinary Research 45 (1984) 67-74
12. Gaubin M., Fanutti C., Mishal Z., Durrbach A., De Berardinis P., Sartorius R., Pozzo G.D., Guardiola J., Perham R.N., and Piatier-Tonneau D. Processing of filamentous bacteriophage virions in antigen-presenting cells targets both HLA class I and class II peptide loading compartments. DNA and Cell Biology 22 (2003) 11-18
13. Grabowska A.M., Jennings R., Laing P., Darsley M., Jameson C.L., Swift L., and Irving W.L. Immunisation with phage displaying peptides representing single epitopes of the glycoprotein G can give rise to partial protective immunity to HSV-2. Virology 269 (2000) 47-53
14. Gruden-Movsesijan A., Ilic N., and Sofronic-Milosavljevic L. Lectin-blot analyses of Trichinella spiralis muscle larvae excretory-secretory components. Parasitology Research 88 (2002) 1004-1007
15. Irving M.B., Pan O., and Scott J.K. Random-peptide libraries and antigen-fragment libraries for epitope mapping and the development of vaccines and diagnostics. Current Opinion in Chemical Biology 5 (2001) 314-324
16. Kapel C.M. Host diversity and biological characteristics of the Trichinella genotypes and their effect on transmission. Veterinary Parasitology 93 (2000) 263-278
17. Lang J.S., Zhan J.B., Xu L.H., and Yan Z.K. Identification of peptide mimetics of xenoreactive α-Gal antigenic epitope by phage display. Biochemical and Biophysical Research Communications 344 (2006) 214-220
18. Li C.K., Chung Y.Y., and Ko R.C. The distribution of excretory/secretory antigens during the muscle phase of Trichinella spiralis and T. pseudospiralis infections. Parasitology Research 85 (1999) 993-998
19. Manoutcharian K., Diaz-Orea A., Gevorkian G., Fragoso G., Acero G., Gonzalez E., de Aluja A., Villalobos N., Gomez-Conde E., and Sciutto E. Recombinant bacteriophage-based multiepitope vaccine against Taenia solium pig cysticercosis. Veterinary Immunology and Immunopathology 99 (2004) 11-24
20. Meloen R.H., Puijk W.C., and Slootstra J.W. Mimotopes: realization of an unlikely concept. Journal of Molecular Recognition 13 (2000) 352-359
21. Meola A., Delmastro P., Monaci P., Luzzago A., Nicosia A., Felici F., Cortese R., and Galfre G. Derivation of vaccines from mimotopes. Immunologic properties of human hepatitis B virus surface antigen mimotopes displayed on filamentous phage. Journal of Immunology 154 (1995) 3162-3172
22. Parhami-Seren B., Krudysz J., and Tsantili P. Affinity panning of peptide libraries using anti-streptokinase monoclonal antibodies: selection of an inhibitor of plasmin(ogen) active site. Journal of Immunological Methods 267 (2002) 185-198
23. Saha S., and Raghava G.P. Prediction of continuous B-cell epitopes in an antigen using recurrent neural network. Proteins 65 (2006) 40-48
24. Takahashi Y., Mingyuan L., and Waikagul J. Epidemiology of Trichinellosis in Asia and the Pacific Rim. Veterinary Parasitology 93 (2000) 227-239
25. Wang G.Y., Sun M.Y., Fang J.B., Yang Q., Tong H.B., and Wang L. Protective immune responses against systemic candidiasis mediated by phage-displayed specific epitope of Candida albicans heat shock protein 90 in C57BL/6J mice. Vaccine 24 (2006) 6065-6073
26. Wang Z.Q., Cui J., Wei H.Y., Han H.M., Zhang H.W., and Li Y.L. Vaccination of mice with DNA vaccine induces the immune response and partial protection against T. spiralis infection. Vaccine 24 (2006) 1205-1212
27. Willis A.E., Perham R.N., and Wraith D. Immunological properties of foreign peptides in multiple display on a filamentous bacteriophage. Gene 128 (1993) 79-83
28. Wu H.C., Yeh C.T., Huang Y.L., Tarn L.J., and Lung C.C. Characterization of neutralizing antibodies and identification of neutralizing epitope mimics on the Clostridium botulinum neurotoxin Type A. Applied and Environmental Microbiology 67 (2001) 3201-3207
29. Wu H.W., Hu X.M., Wang Y., Kurtis J.D., Zeng F.J., McGarvey S.T., Wu G.L., Zhang Z.S., and Hua Z.C. Protective immunity induced by phage displayed mitochondrial related peptides of Schistosoma japonicum. Acta Tropica 99 (2006) 200-207
30. Yang J., Zhu X.P., Yang Y.P., and Lei L.P. Immunological characteristics and protective immunity of the Trichinella spiralis Ts87 antigen. Chinese Journal of Zoology 38 (2003) 52-55 (in Chinese)
31. Yang W.J., Lai J.F., Peng K.C., Chiang H.J., Weng C.N., and Shiuan D. Epitope mapping of Mycoplasma hyopneumoniae using phage displayed peptide libraries and the immune responses of the selected phagotopes. Journal of Immunological Methods 304 (2005) 15-29
32. Yang Y.P., Zhu X.P., Yang J., Lei L.P., and Jing P. Immunohistochemical localization of Ts87 antigen of Trichinella spiralis. Journal of Capital University of Medical Sciences 24 (2003) 108-110 (in Chinese)
33. Yang Y.P., Zhu X.P., Yang J., Zhou L., and Huang S. Immunoscreening and sequence analysis of a cDNA library of adult Trichinella spiralis. Chinese Journal of Parasitology and Parasitic Diseases 20 (2002) 270-273 (in Chinese)
34. Zhu X.P., Yang J., Yang Y.P., Boireau P., Zhan B., Feng J.J., and Hotez P. Prokaryotic expression and characterization of an antigenic gene of adult Trichinella spiralis. Chinese Journal of Parasitology and Parasitic Diseases 21 (2003) 16-19 (in Chinese)