Ethics related to drug therapy in the elderly

Digestive Diseases

Volumn 26, Issue 1, 2007, Pages 28-31

  Beglinger, Christoph ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Adverse effects; Drug metabolism; Elderly patients

Indexed keywords

ANTIBIOTIC AGENT;

AGED; AGING; DOSE LIVER FUNCTION RELATION; DRUG CLEARANCE; DRUG EXCRETION; DRUG HYPERSENSITIVITY; DRUG METABOLISM; DRUG SELECTIVITY; DRUG URINE LEVEL; ELDERLY CARE; HUMAN; KIDNEY FUNCTION; MEDICAL ETHICS; METABOLIC CLEARANCE RATE; PATIENT SAFETY; POLYPHARMACY; PRIORITY JOURNAL; REVIEW; RISK FACTOR;

AGED; AGING; DRUG THERAPY; HUMANS; POLYPHARMACY; RISK ASSESSMENT; RISK FACTORS;

EID: 37349062491     PISSN: 02572753     EISSN: None     Source Type: Journal    
DOI: 10.1159/000109382     Document Type: Review

References (34)

1. Vincent C, Neale G, Woloshynowych M: Adverse events in British hospitals: preliminary retrospective record review. BMJ 2001;322:517-519. http://qshc.bmj.com/cgi/ijlink?linkType=ABST&journalCode=bmj&resid=322/ 7285/517.
2. Turnheim K: When drug therapy gets old: pharmacokinetics and pharmacodynamics in the elderly. Exp Gerontol 2003;38:843-853.
3. Turnheim K: Drug therapy in the elderly. Exp Gerontol 2003;38:843-853.
4. Brennan TA, Leape LL, Laird NM, et al: Incidence of adverse events and negligence in hospitalized patients: results of the Harvard Medical Practice Study I. N Engl J Med 1991;324:370-376.
5. Lehmann FS, Beglinger C: Impact of COX-2 inhibitors in common clinical practice: a gastroenterologist's perspective. Curr Top Med Chem 2005;5:449-464.
6. Wilson RM, Runciman WB, Gibberd RW, et al: The Quality in Australian Health Care Study. Med J Aust 1995;163:458-471.
7. Wilson RM, Harrison BT, Gibberd RW, et al: An analysis of the causes of adverse events from the Quality in Australian Health Care Study. Med J Aust 1999;170:411-415.
8. Davis P, Lay-Yee R, Briant R, et al: Adverse events in New Zealand public hospitals: principal findings from a national survey. Wellington, New Zealand Ministry of Health, 2001.
9. Baker GR, Norton PG, Flintoft V, et al: The Canadian Adverse Events Study: the incidence of adverse events among hospital patients in Canada. Can Med Assoc J 2004;170:1678-1686.
10. Flynn EA, Barker KN, Pepper GA, et al: Comparison of methods for detecting medication errors in 36 hospitals and skilled-nursing facilities. Am J Health Syst Pharm 2002;59:436-446.
11. Dean B: Adverse drug events: what's the truth? Qual Saf Health Care 2003;12:165-166.
12. Schmidt CE, Bottoni T: Improving medication safety and patient care in the emergency department. J Emerg Nurs 2003;29:12-16.
13. Chaudhry SI, Olofinboba KA, Krumholz HM: Detection of errors by attending physicians on a general medicine service. J Gen Intern Med 2003;18:595-600.
14. Uribe CL, Schweikhart SB, Pathak DS, et al: Perceived barriers to medical-error reporting: an exploratory investigation. J Healthc Manag 2002;47:263-279.
15. Kaplan HS, Fastman BR: Organization of event reporting data for sense making and system improvement. Qual Saf Health Care 2003;12(suppl 2):ii68-ii72.
16. Edwards IR, Aronson JK: Adverse drug reactions: definitions, diagnosis, and management. Lancet 2000;356:1255-1259.
17. Walshe K: Adverse events in health care: issues in measurement. Qual Health Care 2000;9:47-52.
18. Nebeker JR, Barach P, Samore MH: Clarifying adverse drug events: a clinician's guide to terminology, documentation, and reporting. Ann Intern Med 2004;140:795-801.
19. Nebeker JR, Hurdle JF, Hoffman J, et al: Developing a taxonomy for research in adverse drug events: potholes and signposts. J Am Med Inform Assoc 2002;9(suppl):S80-S85.
20. Rubin G, George A, Chinn DJ, et al: Errors in general practice: development of an error classification and pilot study of a method for detecting errors. Qual Saf Health Care 2003;12:443-447.
21. Bates DW: Medication errors: how common are they and what can be done to prevent them? Drug Saf 1996;15:303-310.
22. Manasse HR Jr: Medication use in an imperfect world: drug misadventuring as an issue of public policy, part 1. Am J Hosp Pharm 1989;46:929-944.
23. Case RL, Guzzetti PJ: A survey of adverse drug reaction reporting programs in select hospitals. Hosp Pharm 1986;21:423-438.
24. Kaushal R, Bates DW: Information technology and medication safety: what is the benefit? Qual Saf Health Care 2002;11:261-265.
25. Bates DW, Boyle DL, Vander Vliet MB, et al: Relationship between medication errors and adverse drug events. J Gen Intern Med 1995;10:199-205.
26. Morimoto T, Gandhi TK, Seger AC, et al: Adverse drug events and medication errors: detection and classification methods. Qual Saf Health Care 2004;13:306-314.
27. Troutman WG, Doherty KM: Comparison of voluntary adverse drug reaction reports and corresponding medical records. Am J Health Syst Pharm 2003;60:572-575.
28. Brennan TA, Leape LL, Laird NM, et al: Incidence of adverse events and negligence in hospitalized patients: results of the Harvard Medical Practice Study I. N Engl J Med 1991;324:370-377.
29. Wilson RM, Runciman WB, Gibberd RW, Harrison BT, Newby L, Hamilton JD: The Quality in Australian Health Care Study. Med J Aust 1995;163:458-476.
30. Leape LL, Brennan TA, Laird N, et al: The nature of adverse events in hospitalized patients: results of the Harvard Medical Practice Study II. N Engl J Med 1991;324:377-384.
31. Thomas EJ, Studdert DM, Burstin HR, et al: Incidence and types of adverse events and negligent care in Utah and Colorado. Med Care 2000;38:261-271.
32. Davis P, Lay-Yee R, Briant R, et al: Adverse events in New Zealand public hospitals: principal findings from a national survey (occasional paper No 3). Wellington: NZ Ministry of Health, 2001. www.moh.govt.nz/publications/ adverseevents.
33. Davis P, Lay-Yee R, Briant R, Ali W, Scott A, Schug S: Adverse events in New Zealand public hospitals. II. Preventability and clinical context. N Z Med J 2003;116:U624.
34. Reason J: Human error: models and management. BMJ 2000;320:768-770.