Tumorigenic adenovirus type 12 E1A inhibits phosphorylation of NF-κB by PKAc, causing loss of DNA binding and transactivation

Journal of Virology

Volumn 82, Issue 1, 2008, Pages 40-48

  Guan, Hancheng ^a   Jiao, Junfang ^a   Ricciardi, Robert P ^a,b,c  

^a School of Veterinary Medicine   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA; E1A 12 PROTEIN; E1A 5 PROTEIN; E1A PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN KINASE AC; PROTEIN P50; PROTEIN SUBUNIT; SERINE; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENOVIRUS 12; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; CELL SURFACE; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DNA BINDING; ENHANCER REGION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN STABILITY; TRANSACTIVATION; TRANSCRIPTION REGULATION; VIRUS CARCINOGENESIS;

ADENOVIRIDAE; ADENOVIRUS E1A PROTEINS; ANIMALS; CELL LINE; CRICETINAE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA-BINDING PROTEINS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MICE; NF-KAPPA B; PHOSPHORYLATION; PROTEIN BINDING; RATS; TRANS-ACTIVATION (GENETICS);

HUMAN ADENOVIRUS TYPE 12;

EID: 37349051694     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01579-07     Document Type: Article

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