Sea urchin embryonic development provides a model for evaluating therapies against β-amyloid toxicity

Brain Research Bulletin

Volumn 75, Issue 1, 2008, Pages 94-100

  Buznikov, Gennady A ^a   Nikitina, Lyudmila A ^a   Bezuglov, Vladimir V ^b   Milošević, Ivan ^c   Lazarević, Lidija ^c   Rogač, Ljubica ^c   Ruzdijić, Sabera ^d   Slotkin, Theodore A ^e   Rakić, Ljubiša M ^f  

^a KOL TSOV INSTITUTE OF DEVELOPMENTAL BIOLOGY   (Russian Federation)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^c Institute of Marine Biology   (Serbia)

^d UNIVERSITY OF BELGRADE   (Serbia)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

^f SERBIAN ACADEMY OF SCIENCES AND ARTS   (Serbia)

Author keywords

Amyloid; Acetylcholine; Alzheimer's disease; Cannabinoids; Development; Sea urchin embryo; Serotonin

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINE DERIVATIVE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; ARACHIDONOYL 5 HYDROXYTRYPTAMINE; ARACHIDONOYL DIMETHYLAMINOETHANOL; ARACHIDONOYL VANILLYLAMINE; CANNABINOID; MORPHOGEN; NEUROTRANSMITTER; SEROTONIN; SEROTONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLASTULA; CELL CYCLE; CELL DIVISION; CHOLINERGIC ACTIVITY; CONCENTRATION RESPONSE; CYTOTOXICITY; DIGESTIVE SYSTEM; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; GASTRULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEA URCHIN; SENSITIVITY ANALYSIS;

AGE FACTORS; AMYLOID BETA-PROTEIN; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; NEUROTOXICITY SYNDROMES; NEUROTRANSMITTER AGENTS; PEPTIDE FRAGMENTS; SEA URCHINS;

EID: 37349046293     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2007.07.026     Document Type: Article

References (40)

1. Akaike A. Preclinical evidence of neuroprotection by cholinesterase inhibitors. Alzheimer Dis. Assoc. Disorders 20 (2006) S8-S11
2. Araki H., Suemaru K., and Gomita Y. Neuronal nicotinic receptor and psychiatric disorders: functional and behavioral effects of nicotine. Jpn. J. Pharmacol. 88 (2002) 133-138
3. Bezuglov V.V., Manevich Y., Archakov A.V., Bobrov M.Y., Kuklev D.V., Petrukhina G.N., Makarov V.A., and Buznikov G.A. Artificially functionalized polyenoic fatty acids as new lipid bioregulators. Russ. J. Bioorg. Chem. 23 (1997) 190-198
4. Bezuglov V.V., Zinchenko G.N., Nikitina L.A., and Buznikov G.A. Arachidonoylcholine and O-arachidonoyldimethylaminoethanol as new cholinergic substances. Russ. J. Bioorg. Chem. 207 (2000) 200-203
5. Bezuglov V.V., Zinchenko G.N., Nikitina L.A., and Buznikov G.A. Arachidonoylcholine and O-arachidonoyldimethylaminoethanol as new cholinergic substances. Russ. J. Bioorg. Chem. 207 (2001) 200-203
6. Buznikov G.A. Sea urchin embryos as a test system to detect embryotoxicity of chemical compounds. Biol. Int. 8 (1983) 5-8
7. Buznikov G.A. Neurotransmitters in Embryogenesis (1990), Harwood Academic Publishers, Chur, Switzerland
8. Buznikov G.A., and Bezuglov V.V. 5-Hydroxytryptamides and 3-hydroxytyramides of polyenoic fatty acids as a tool for studying the pre-nervous biogenic monoamines functions. Russ. Physiol. J. 86 (2000) 1093-1108
9. Buznikov G.A., Bezuglov V.V., Nikitina L.A., Slotkin T.A., and Lauder J.M. Cholinergic regulation of sea urchin embryonic and larval development. Russ. J. Physiol. 87 (2001) 1548-1556
10. Buznikov G.A., Jokanovic M., Kovacevic N., and Rakic L. Sea urchin embryos and larvae as biosensors for screening and detailed study of pharmacologically active substances. Arch. Toxicol. Kinet. Xenobiot. Metab. 5 (1997) 393-400
11. Buznikov G.A., Kost A.N., Kucherova N.F., Mndzhoyan A.L., Suvorov N.N., and Berdysheva L.V. The role of neurohumours in early embryogenesis. 3. Pharmacological analysis of the role of neurohumours in cleavage divisions. J. Embryol. Exp. Morphol. 23 (1970) 549-569
12. Buznikov G.A., Nikitina L.A., Bezuglov V.V., Francisco M.E., Obispo-Peak I.N., Peterson R.A., Slotkin T.A., Lauder J.M., and Rakic L. New perspectives on roles for neurotransmitters in early ("pre-nervous") embryogenesis. In: Ruždijić S., and Rakić L. (Eds). Neurobiological Studies-From Genes to Behaviour (2007), Signpost/Transworld Research Network, Kerala, India 183-196
13. Buznikov G.A., Nikitina L.A., Bezuglov V.V., Lauder J.M., Padilla S., and Slotkin T.A. An invertebrate model of the developmental neurotoxicity of insecticides: effects of chlorpyrifos and dieldrin in sea urchin embryos and larvae. Environ. Health Perspect. 109 (2001) 651-661
14. Buznikov G.A., Nikitina L.A., Rakić L.M., Milošević I., Bezuglov V.V., Lauder J.M., and Slotkin T.A. The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: therapeutic interventions and a comparison with the monoamine depleter, reserpine. Brain Res. Bull. 74 (2007) 221-231
15. Buznikov G.A., Peterson R.E., Nikitina L.A., Bezuglov V.V., and Lauder J.M. The pre-nervous serotonergic system of developing sea urchin embryos and larvae: pharmacologic and immunocytochemical evidence. Neurochem. Res. 30 (2005) 825-837
16. Buznikov G.A., and Podmarev V.I. The sea urchins Strongylocentrotus droebachiensis, S. nudus and S. intermedius. In: Dettlaff T.A., and Vassetzky S.G. (Eds). Animal Species for Developmental Studies, vol. 1: Invertebrates (1990), Consultants Bureau, New York, London 251-283
17. Buznikov G.A., and Rakic L. Cholinoreceptors of early (pre-nervous) sea urchin embryos. Neurosci. Behav. Physiol. 30 (2000) 53-62
18. Buznikov G.A., Shmukler Y.B., and Lauder J.M. From oocyte to neuron: do neurotransmitters function in the same way throughout development?. Cell. Mol. Neurobiol. 16 (1996) 532-559
19. Buznikov G.A., Slotkin T.A., and Lauder J.M. Sea urchin embryos and larvae as biosensors for neurotoxins. In: Maines M.D., Costa L.G., Hodgson E., and Reed D.J. (Eds). Current Protocols in Toxicology (2003), John Wiley & Sons, New York 1.6.1-1.6.24
20. Carrotta R., Di Carlo M., Manno M., Montana G., Picone P., Romancino D., and San Biagio P.L. Toxicity of recombinant β-amyloid prefibrillar oligomers on the morphogenesis of the sea urchin Paracentrotus lividus. FASEB J. 20 (2006) E301-E308
21. Crowther D.C., Page R., Chandraratna D., and Lomas D.A. A Drosophila model of Alzheimer's disease. Methods Enzymol. 412 (2006) 234-255
22. Dreyfus C.F. Neurotransmitters and neurotrophins collaborate to influence brain development. Perspect. Dev. Neurobiol. 5 (1998) 389-399
23. Esposito G., De Filippis D., Steardo L., Scuderi C., Savani C., Cuomo V., and Iuvone T. CB1 receptor selective activation inhibits β-amyloid-induced iNOS protein expression in C6 cells and subsequently blunts tau protein hyperphosphorylatio in co-cultured neurons. Neurosci. Lett. 404 (2006) 342-346
24. Giacobini E. Cholinomimetic therapy of Alzheimer disease: does it slow down deterioration?. In: Racagni G., Brunello N., and Langer S.Z. (Eds). Recent Advances in the Treatment of Neurodegenerative Disorders and Cognitive Dysfunction (1994), S. Karger, Basel, Switzerland 51-57
25. Gustafson T., and Toneby M. On the role of serotonin and acetylcholine in sea urchin morphogenesis. Exp. Cell Res. 62 (1970) 102-117
26. Hagstrom B.E., and Lonning S. The sea urchin egg as a testing object in toxicology. Acta Pharmacol. Toxicol. 32 (1973) 1-39
27. + currents of Drosophila larval cholinergic neurons. J. Neurobiol. 66 (2006) 476-487
28. Link C.D. C.elegans models of age-associated neurodegenerative diseases: lessons from transgenic worm models of Alzheimer's disease. Exp. Gerontol. 41 (2006) 1007-1013
29. Nallapaneni A., Liu J., Karanth S., and Pope C. Modulation of paraoxon toxicity by the cannabinoid receptor agonist WIN 55, 212-2. Toxicology 227 (2006) 173-183
30. Nordberg A. Mechanisms behind the neuroprotective actions of cholinesterase inhibitors in Alzheimer disease. Alzheimer Dis. Assoc. Disorders 20 (2006) S12-S18
31. Qiao D., Nikitina L.A., Buznikov G.A., Lauder J.M., Seidler F.J., and Slotkin T.A. The sea urchin embryo as a model for mammalian developmental neurotoxicity: ontogenesis of the high-affinity choline transporter and its role in cholinergic trophic activity. Environ. Health Perspect. 111 (2003) 1730-1735
32. Rusted J.M., Newhouse P.A., and Levin E.D. Nicotinic treatment for degenerative neuropsychiatric disorders such as Alzheimer's disease and Parkinson's disease. Behav. Brain Res. 113 (2000) 121-129
33. Scatena R., Martorana G.E., Bottoni P., Botta G., Pastore P., and Giardina B. An update on pharmacological approach to neurodegenerative diseases. Expert Opin. Investig. Drugs 16 (2007) 59-72
34. Serretti A., Artioli P., Quartesan R., and DeRonchi D. Genes involved in Alzheimer's disease: a survey of possible candidates. J. Alzheimers Dis. 7 (2005) 331-353
35. Shmukier Y.B., and Buznikov G.A. Functional coupling of neurotransmitters with second messengers during cleavage divisions: facts and hypotheses. Perspect. Dev. Neurobiol. 5 (1998) 469-483
36. Small D.H., and Fodero L.R. Cholinergic regulation of synaptic plasticity as a therapeutic target in Alzheimer's disease. J. Alzheimers Dis. 4 (2002) 349-355
37. Verdier Y., and Penke B. Polypeptide and protein aggregates with neurotoxic properties in neurodegenerative disorders: emphasis on β-amyloid-induced dysfunction of receptor-mediated signal transduction pathways. Curr. Signal Transduct. Ther. 1 (2006) 97-112
38. Whitaker-Azmitia P.M. Serotonin and brain development: role in human developmental diseases. Brain Res. Bull. 56 (2001) 479-485
39. Wu Y., and Luo Y. Transgenic C. elegans as a model in Alzheimer's research. Curr. Alzheimer Res. 2 (2005) 37-45
40. Zamani M.R., and Allen Y.S. Nicotine and its interaction with β-amyloid protein: a short review. Biol. Psychiat. 49 (2001) 221-232