Methanolic extract of Entandrophragma angolense induces gastric mucus cell counts and gastric mucus secretion

Journal of Biological Sciences

Volumn 7, Issue 8, 2007, Pages 1531-1534

  Oluwole, F S ^a   Omolaso, B O ^a   Ayo, J A ^a  

^a UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Antioxidants; Entandrophragma angolense; Gastric mucus secretion; Malonialdehyde concentration; Mucus cell count; Oxygen radicals

Indexed keywords

ALCOHOL; ANTIULCER AGENT; ENTANDROPHRAGMA ANGOLENSE EXTRACT; MALONALDEHYDE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BARK; CELL ACTIVITY; CELL COUNT; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; ENTANDROPHRAGMA ANGOLENSE; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; MEDICINAL PLANT; MUCUS SECRETION; NONHUMAN; RAT; SOLVENT EXTRACTION; STOMACH MUCUS;

ANIMALIA; ENTANDROPHRAGMA ANGOLENSE; RATTUS;

EID: 37349035642     PISSN: 17273048     EISSN: 18125719     Source Type: Journal    
DOI: 10.3923/jbs.2007.1531.1534     Document Type: Article

References (12)

1. Azzumi, Y., T. Ichikawa, K. Ishihara and K. Hotta, 1993. The validity of the ethanol precipitation method for the measurement of mucin content in human gastric juices and its relationship to gastrodoudenal disease. Clin. Chim. Acta, 221: 219-225.
2. Bjorne, H., J. Petersson, M. Phillipson, E. Weitzberg, L. Holm and J.O. Lundberg, 2004. Nitrite in saliva increases gastric mucosal blood flow and mucus thickness. J. Clin. Invest., 113: 106-114.
3. Desai, J.K., K. Goyal and R. Parmer, 1997. Pathogenesis of peptic ulcer disease and current trends in therapy. India J. Physiol. Pharmacol., 41: 3-15.
4. Freeman, B.A. and J.D. Crapo, 1982. Biology of disease: Free radicals and tissue injury. Lab. Invests, pp: 412.
5. Garg, G.P., S.K. Nigam and C.W. Ogle, 1993. The gastric antiulcer effects of the leaves of the neem tree. Planta Medica, 59: 215-217.
6. Gutteridge, J.M.C. and C. Wilkins, 1982. Copper dependent hydroxyl radical damage to ascorbic acid: Formation of a Thiobarbituric acid reactive product. FEBS. Lett., 137: 327-340.
7. Halliwell, B. and J.M.C. Gutteridge, 1990. Role of free radical and catalytic metal ions in human disease: An overview. Methods Ezymol., 186: 1-85.
8. Kelly, F.J., 1998. The causes of antioxidant in the prevention treatment of disease. J.I.G. Co., 40: 21-23.
9. Li Ma, P.D. Soldato and L. John, 2002. Divergent effects of new cycloxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance. Pharmacology, 99: 13243-13247.
10. Mojzis, R., R. Hegedusova and L. Mirossay, 2000. Role of mucus in ischemia/Reperfurion-induced gastric mucosal injury in rats. Physiol. Res., 49: 441-446.
11. Njar, V.C., J.K. Adesanwo and Y. Raji, 1995. The antiulcer agent of the stem bark of Entandrophragma angolense. Planta Med., 61: 91-92
12. 14C aminophyrine accumulation and cyclic monophosphate generation by isolated canine parietal cells. J. Gastroenterol., 83: 216-233.