Radiosterilization of drugs in aqueous solutions may be achieved by the use of radioprotective excipients

International Journal of Pharmaceutics

Volumn 349, Issue 1-2, 2008, Pages 74-82

  Maquille, Aubert ^a   Jiwan, Jean Louis Habib ^a   Tilquin, Bernard ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

HPLC DAD; LC MS; Metoclopramide hydrochloride; Radiolysis; Radioprotective excipients

Indexed keywords

DRUG ADDITIVE; MANNITOL; METOCLOPRAMIDE; NICOTINAMIDE; PYRIDOXINE;

AQUEOUS SOLUTION; ARTICLE; DIODE; DRUG DEGRADATION; DRUG POTENCY; ELECTRON; ELECTRON BEAM; EXCIPIENT COMPATIBILITY; GAMMA IRRADIATION; GAMMA RADIATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IRRADIATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; RADIATION STERILIZATION; RADIOLYSIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; COLOR; ELECTRONS; EXCIPIENTS; GAMMA RAYS; MANNITOL; MASS SPECTROMETRY; NIACINAMIDE; PHARMACEUTICAL PREPARATIONS; PHARMACEUTICAL SOLUTIONS; PYRIDOXINE; RADIATION-PROTECTIVE AGENTS; RADIOMETRY; STERILIZATION; WATER;

EID: 37349029651     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.07.024     Document Type: Article

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