Electron beam and gamma radiolysis of solid-state metoclopramide

Pharmaceutical Research

Volumn 23, Issue 6, 2006, Pages 1343-1349

  Maquille, Aubert ^a   Slegers, Catherine ^a   Habib, Jean Louis ^a   Tilquin, Bernard ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Final products analysis; HPLC DAD; LC MS; Metoclopramide hydrochloride; Radiolysis

Indexed keywords

CHLORINE; METOCLOPRAMIDE; POLY(METHYL METHACRYLATE);

AREA UNDER THE CURVE; ARTICLE; DIODE; DRUG DEGRADATION; ELECTRON; ELECTRON BEAM; GAMMA RADIATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RADIOLYSIS; SOLID STATE; TANDEM MASS SPECTROMETRY;

ANTIEMETICS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; ELECTRONS; GAMMA RAYS; MASS SPECTROMETRY; METOCLOPRAMIDE; MOLECULAR STRUCTURE; STERILIZATION; TECHNOLOGY, PHARMACEUTICAL;

EID: 33745416602     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-0019-x     Document Type: Article

References (22)

1. European Pharmacopoeia, 5th ed., Council of Europe, Strasbourg, 2005.
2. The United States Pharmacopeia National Formulary 24, United States Pharmacopeial Convention, Rockville, MD, 2000.
3. A. S. Crucq C. Slegers V. Deridder B. Tilquin 2000 Radiosensitivity study of cefazolin sodium Talanta 52 873 877
4. N. Barbarin A. S. Crucq B. Tilquin 1996 Study of volatile compounds from the radiosterilization of solid cephalosporins Radiat. Phys. Chem. 48 787 794
5. The European Agency for the Evaluation of Medicinal Products (EMEA). Decisional Trees for the Selection of Sterilization Methods (CPMP/QWP/054/98), EMEA, London, 1999.
6. A. Engalytcheff J. P. Vanhellepute B. Tilquin 2004 HPLC detection and quantification of radiolytic products of eight β-blockers irradiated in the solid state and hypotheses on their origins Pharm. Res. 21 1103 1108
7. G. P. Jacobs 1985 A review: radiation sterilization of pharmaceuticals Radiat. Phys. Chem. 6 133 142
8. N. Barbarin B. Tilquin E. de Hoffmann 2001 Radiosterilization of cefotaxime: investigation of potential degradation compounds by liquid chromatography-electrospray mass spectrometry J. Chromatogr. A 929 51 61
9. P. Horsch L. Bigler H. R. Altorfer 2001 Influence of radiation sterilization on the stability of trifluorothymidine Int. J. Pharm. 222 205 215
10. A. Engalytcheff R. Debuyst G. C. A. M. Vanhaelewyn F. J. Callens B. Tilquin 2004 Attempts at correlation of the radiolytic species of irradiated solid-state captopril studied by multi-frequency EPR and HPLC Radiat. Res. 162 616 622
11. K. W. Bögl 1990 Methods for identification of irradiated food Radiat. Phys. Chem. 35 301 310
12. B. G. Katzung 1998 Basic and Clinical Pharmacology 7th ed. Appleton & Lange, McGraw-Hill New York
13. I. Colman M. D. Brown G. D. Innes E. Grafstein T. E. Roberts B. H. Rowe 2004 Parenteral metoclopramide for acute migraine: meta-analysis of randomized controlled trials Br. Med. J. 329 1369 1373
14. G. Damian 2003 EPR investigation of γ-irradiated anti-emetic drugs Talanta 60 923 927
15. A. Engalytcheff V. Deridder R. Debuyst B. Tilquin 2003 Determination of radical yields in solid-state drugs as one technique to identify drugs that will withstand radiosterilization: radioresistance of beta-blockers Radiat. Res. 160 103 109
16. The European Agency for the Evaluation of Medicinal Products (EMEA). ICH Topic Q3A Note for Guidance on Impurities Testing: Impurities in New Drug Substances (CPMP/ICH/2737/99), EMEA, London, 2002.
17. J. W. T. Spinks R. J. Woods 1990 Introduction to Radiation Chemistry 3rd ed. Wiley Interscience New York
18. J. E. Willard 19987 Radiation chemistry of organic solids Farhataziz M. A. J. Rodgers Radiation Chemistry Principles and Applications VCH New York 395 434
19. C. Boess K. W. Bögl 1996 Influence of radiation treatment on pharmaceuticals-a review: alkaloids, morphine derivatives, and antibiotics Drug Dev. Ind. Pharm. 22 495 529
20. A. S. Crucq V. Deridder B. Tilquin 2005 Radiostability of pharmaceuticals under different irradiation conditions Radiat. Phys. Chem. 72 355 361
21. N. Barbarin B. Tilquin 2001 Study of nonvolatile degradation compounds produced by radiosterilization of cefotaxime Radiat. Phys. Chem. 60 359 367
22. A. V. Amossov A. O. Rybaltovsky 1994 Radiation color center formation in silica glasses: a review of photo- and thermo-chemical aspects of the problem J. Non-Cryst. Solids 179 4 226 234