Sphingosine-1-phosphate-induced oxygen free radical generation in smooth muscle cell migration requires Gα12/13 protein-mediated phospholipase C activation

Journal of Vascular Surgery

Volumn 46, Issue 6, 2007, Pages

  Roztocil, Eliza ^a   Nicholl, Suzanne M ^a   Davies, Mark G ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; OXYGEN RADICAL; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SMALL INTERFERING RNA; SPHINGOSINE 1 PHOSPHATE;

ANGIOPLASTY; ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HYPERPLASIA; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; RAT; RESTENOSIS; SIGNAL TRANSDUCTION; STENT; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; ENZYME ACTIVATION; ESTRENES; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; LYSOPHOSPHOLIPIDS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASE; ONIUM COMPOUNDS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERTUSSIS TOXIN; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPASE C BETA; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PYRROLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPHINGOSINE; TIME FACTORS;

EID: 37249089788     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvs.2007.08.013     Document Type: Article

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