Modeling of a biphasic membrane reactor catalyzed by lipase immobilized in a hydrophilic/hydrophobic composite membrane

Journal of Membrane Science

Volumn 308, Issue 1-2, 2008, Pages 242-249

  Hu, Yu ^a   Wang, Yujun ^a   Luo, Guangsheng ^a   Dai, Youyuan ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

Composite membrane; Hydrolysis; Lipase immobilization; Reaction diffusion model

Indexed keywords

DIFFUSION; HYDROLYSIS; HYDROPHILICITY; MATHEMATICAL MODELS;

LIPASE IMMOBILIZATION; REACTION-DIFFUSION MODEL;

COMPOSITE MEMBRANES;

CELLULOSE ACETATE; POLITEF; TRIACYLGLYCEROL LIPASE;

COMPOSITE MEMBRANES; DIFFUSION; HYDROLYSIS; HYDROPHILICITY; MATHEMATICAL MODELS;

ARTICLE; CALCULATION; CATALYSIS; CHEMICAL REACTION; DIFFUSION; ENZYME IMMOBILIZATION; HYDROLYSIS; KINETICS; MEMBRANE REACTOR; MODEL; PRIORITY JOURNAL; SEPARATION TECHNIQUE;

EID: 37249059769     PISSN: 03767388     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.memsci.2007.09.064     Document Type: Article

References (16)

1. Grochulski P., Li Y.G., Schrag J.D., et al. Insights into interfacial activation from an open structure of Candida rugosa lipase. J. Mol. Catal. B: Enzym. 268 (1993) 12843-12847
2. Sarada L., and Desnuelle P. Action de la lipase pancreatique sur les esters en emulsion. Biochim. Biophys. Acta 30 (1958) 513-521
3. Matsumoto M., and Ohashi K. Effect of immobilization on thermostability of lipase from Candida rugosa. Biochem. Eng. J. 14 (2003) 75-77
4. Giorno L., Zahang J.C., Drioli E., et al. Study of mass transfer performance of naproxen acid and ester through a multiphase enzyme-loaded membrane system. J. Membr. Sci. 276 (2006) 59-67
5. Long W.S., Bhatia S., and Kamaruddin A. Modeling and simulation of enzymatic membrane reactor for kinetic resolution of ibuprofen ester. J. Membr. Sci. 219 (2003) 69-88
6. Trusek-Holownia A. A catalytic membrane for hydrolysis reaction carried out in the two-liquid phase system: membrane preparation and characterization, mathematical model of the process. J. Membr. Sci. 259 (2005) 74-84
7. Curcio S., Calabro V., and Iorio G. A theoretical and experimental analysis of a membrane bioreactor performance in recycle configuration. J. Membr. Sci. 273 (2006) 129-142
8. Xu J., Wang Y.J., Hu Y., et al. Candida rugosa lipase immobilized by a specially designed microstructure in the PVA/PTFE composite membrane. J. Membr. Sci. 281 (2006) 410-416
9. Xu J., Wang Y.J., Hu Y., et al. Immobilization of lipase by filtration into a specially designed microstructure in the CA/PTFE composite membrane. J. Mol. Catal. B: Enzym. 42 (2006) 55-63
10. Wang Y.J., Hu Y., Xu J., et al. Immobilization of lipase with a special microstructure in composite hydrophilic CA/hydrophobic PTFE membrane for the chiral separation of racemic ibuprofen. J. Membr. Sci. 293 (2007) 133-141
11. Long W.S., Kamaruddin A., and Bhatia S. Chiral resolution of racemic ibuprofen ester in an enzymatic membrane reactor. J. Membr. Sci. 247 (2005) 185-200
12. Tsai S.W., and Shaw S.S. Selection of hydrophobic membranes in the lipase-catalyzed hydrolysis of olive oil. J. Membr. Sci. 146 (1998) 1-8
13. Jones E., and Weatherley L.R. Modelling the kinetics of lipase-catalysed oil hydrolysis in an electrically enhanced liquid-liquid system. J. Chem. Technol. Biotechnol. 78 (2003) 194-198
14. Maruyama T., Nakajima M., Ichikawa S., et al. Oil-water interfacial activation of lipase for interesterification of triglyceride and fatty acid. J. Am. Chem. Soc. 77 (2000) 1121-1126
15. Cygler M., and Schrag J.D. Structure and conformational flexibility of Candida rugosa lipase. Biochim. Biophys. Acta. 1441 (1999) 205-214
16. Bouwer S.T., Cuperus F.P., and Derksen J.T.P. The performance of enzyme-membrane reactors with immobilized lipase. Enzyme Microb. Technol. 21 (1997) 291-296