Assays of ligand-human serum albumin binding using pulsed ultrafiltration and liquid chromatography-mass spectrometry

Combinatorial Chemistry and High Throughput Screening

Volumn 2, Issue 6, 1999, Pages 353-359

  Gu, Chungang ^a   Nikolic, Dejan ^a   Lai, Jacob ^a   Xu, Xiaoying ^a   Van Breemen, Richard B ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COUMARIN DERIVATIVE; DANSYL CHLORIDE; SARCOSINE; SERUM ALBUMIN; WARFARIN;

ARTICLE; BINDING AFFINITY; DRUG PROTEIN BINDING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN DETERMINATION; ULTRAFILTRATION;

CHROMATOGRAPHY, LIQUID; DANSYL COMPOUNDS; HUMANS; LIGANDS; MASS SPECTROMETRY; SARCOSINE; SERUM ALBUMIN; ULTRAFILTRATION; WARFARIN;

EID: 0033379553     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Winzor, D. J.; Sawyer, W. H. Quantitative Characterization of Ligand Binding, John Wiley & Sons: New York, 1995.
2. Hulme, E. C. Receptor-Ligand Interactions, a Practical Approach, IRL Press: Oxford, UK, 1992
3. van Breemen, R. B.; Huang, C.-H.; Nikolic, D.; Woodbury, C. P.; Zhao, Y.-Z.; Venton, D. L. Anal. Chem., 1997, 69, 2159-2164.
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6. van Breemen, R. B.; Woodbury, C. P.; Venton, D. L. "Screening molecular diversity using mass spectrometry." In Mass Spectrometry of Biological Molecules, 2nd ed. Ed. by B. S. Larsen and C. N. McEwen, Marcel Dekker, New York, pp. 99-113, 1998.
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8. van Breemen, R. B.; Nikolic, D.; Bolton, J. L. Drug Metab. Dispos. 1998, 26, 85-90
9. Nikolic, D.; Fan, P. W.; Bolton, J. L.; van Breemen, R. B. Combin. Chem. High Throughput Screen. 1999, 2, 165-176.
10. Klotz, I. M. Ligand Receptor Energetics: A Guide for the Perplexed, p. 63, John Wiley & Sons: New York, 1997.