메뉴 건너뛰기




Volumn 16, Issue 105, 2007, Pages 98-104

Where current pharmacological therapies fall short in COPD: Symptom control is not enough

Author keywords

2 Agonists; Chronic obstructive pulmonary disease; Disease progression; Inflammation; Inhaled corticosteroid

Indexed keywords

ANTIINFLAMMATORY AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; CORTICOSTEROID; FLUTICASONE PROPIONATE; FLUTICASONE PROPIONATE PLUS SALMETEROL; LONG ACTING DRUG; SALMETEROL;

EID: 37249001261     PISSN: 09059180     EISSN: None     Source Type: Journal    
DOI: 10.1183/09059180.00010503     Document Type: Conference Paper
Times cited : (17)

References (49)
  • 1
    • 37249070545 scopus 로고    scopus 로고
    • Global Initiative for Chronic Obstructive Lung Disease. Executive summary: global strategy for the diagnosis, management, and prevention of COPD, 2006. www.goldcopd.com. Date last updated: November 2006. Date last accessed: June 19, 2007.
    • Global Initiative for Chronic Obstructive Lung Disease. Executive summary: global strategy for the diagnosis, management, and prevention of COPD, 2006. www.goldcopd.com. Date last updated: November 2006. Date last accessed: June 19, 2007.
  • 2
    • 0038101688 scopus 로고    scopus 로고
    • COPD: Problems in diagnosis and measurement
    • s
    • Weiss ST, DeMeo DL, Postma DS. COPD: problems in diagnosis and measurement. Eur Respir J 2003; 21: Suppl. 41, 4s-12s.
    • (2003) Eur Respir J , vol.21 , Issue.SUPPL. 41
    • Weiss, S.T.1    DeMeo, D.L.2    Postma, D.S.3
  • 3
    • 37249087418 scopus 로고    scopus 로고
    • Morbidity and Mortality Chartbook
    • National Heart, Lung and Blood Institute, National Heart, Lung and Blood Institute
    • National Heart, Lung and Blood Institute. Morbidity and Mortality Chartbook. Bethesda, National Institutes for Health, National Heart, Lung and Blood Institute, 2000.
    • (2000) Bethesda, National Institutes for Health
  • 4
    • 0036682945 scopus 로고    scopus 로고
    • Can GOLD Stage 0 provide information of prognostic value in chronic obstructive pulmonary disease?
    • Vestbo J, Lange P. Can GOLD Stage 0 provide information of prognostic value in chronic obstructive pulmonary disease? Am J Respir Crit Care Med 2002; 166: 329-332.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 329-332
    • Vestbo, J.1    Lange, P.2
  • 5
    • 3142517968 scopus 로고    scopus 로고
    • Association between chronic obstructive pulmonary disease and systemic inflammation: A systematic review and a meta-analysis
    • Gan WQ, Man SF, Senthilselvan A, Sin DD. Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis. Thorax 2004; 59: 574-580.
    • (2004) Thorax , vol.59 , pp. 574-580
    • Gan, W.Q.1    Man, S.F.2    Senthilselvan, A.3    Sin, D.D.4
  • 9
    • 37249058294 scopus 로고    scopus 로고
    • Inflammation in COPD: A link to systemic comorbidities
    • Rennard SI. Inflammation in COPD: a link to systemic comorbidities. Eur Respir Rev 2007; 16: 91-97.
    • (2007) Eur Respir Rev , vol.16 , pp. 91-97
    • Rennard, S.I.1
  • 10
    • 33744799127 scopus 로고    scopus 로고
    • Cytokines as targets in chronic obstructive pulmonary disease
    • Chung KF. Cytokines as targets in chronic obstructive pulmonary disease. Curr Drug Targets 2006; 7: 675-681.
    • (2006) Curr Drug Targets , vol.7 , pp. 675-681
    • Chung, K.F.1
  • 11
    • 0033773688 scopus 로고    scopus 로고
    • Balance of matrix metalloprotease-9 and tissue inhibitor of metalloprotease-1 from alveolar macrophages in cigarette smokers. Regulation by interleukin-10
    • Lim S, Roche N, Oliver BG, Mattos W, Barnes PJ, Fan CK. Balance of matrix metalloprotease-9 and tissue inhibitor of metalloprotease-1 from alveolar macrophages in cigarette smokers. Regulation by interleukin-10. Am J Respir Crit Care Med 2000; 162: 1355-1360.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1355-1360
    • Lim, S.1    Roche, N.2    Oliver, B.G.3    Mattos, W.4    Barnes, P.J.5    Fan, C.K.6
  • 12
    • 26944434702 scopus 로고    scopus 로고
    • Reducing airways inflammation to prevent exacerbations in chronic obstructive pulmonary disease
    • Roche N, Huchon G. Reducing airways inflammation to prevent exacerbations in chronic obstructive pulmonary disease. Allergy 2005; 60: 1350-1356.
    • (2005) Allergy , vol.60 , pp. 1350-1356
    • Roche, N.1    Huchon, G.2
  • 13
    • 0141928029 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: Molecular and cellular mechanisms
    • Barnes PJ, Shapiro SD, Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J 2003; 22: 672-688.
    • (2003) Eur Respir J , vol.22 , pp. 672-688
    • Barnes, P.J.1    Shapiro, S.D.2    Pauwels, R.A.3
  • 14
    • 33745209743 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease, inflammation and co-morbidity - a common inflammatory phenotype?
    • Sevenoaks MJ, Stockley RA. Chronic obstructive pulmonary disease, inflammation and co-morbidity - a common inflammatory phenotype? Respir Res 2006; 7: 1-9.
    • (2006) Respir Res , vol.7 , pp. 1-9
    • Sevenoaks, M.J.1    Stockley, R.A.2
  • 15
    • 4444331230 scopus 로고    scopus 로고
    • Treatment of stable chronic obstructive pulmonary disease
    • Rennard SI. Treatment of stable chronic obstructive pulmonary disease. Lancet 2004; 364: 791-802.
    • (2004) Lancet , vol.364 , pp. 791-802
    • Rennard, S.I.1
  • 16
    • 33744770621 scopus 로고    scopus 로고
    • Efficacy and safety of inhaled corticosteroids in patients with COPD: A systematic review and meta-analysis of health outcomes
    • Gartlehner G, Hansen RA, Carson SS, Lohr KN. Efficacy and safety of inhaled corticosteroids in patients with COPD: a systematic review and meta-analysis of health outcomes. Ann Fam Med 2006; 4: 253-262.
    • (2006) Ann Fam Med , vol.4 , pp. 253-262
    • Gartlehner, G.1    Hansen, R.A.2    Carson, S.S.3    Lohr, K.N.4
  • 17
    • 0035691665 scopus 로고    scopus 로고
    • Guidelines versus clinical practice in the treatment of chronic obstructive pulmonary disease
    • Roche N, Lepage T, Bourcereau J, Terrioux P. Guidelines versus clinical practice in the treatment of chronic obstructive pulmonary disease. Eur Respir J 2001; 18: 903-908.
    • (2001) Eur Respir J , vol.18 , pp. 903-908
    • Roche, N.1    Lepage, T.2    Bourcereau, J.3    Terrioux, P.4
  • 18
    • 0034955633 scopus 로고    scopus 로고
    • Dose dependent increased mortality risk in COPD patients treated with oral glucocorticoids
    • Schols AM, Wesseling G, Kester AD, et al. Dose dependent increased mortality risk in COPD patients treated with oral glucocorticoids. Eur Respir J 2001; 17: 337-342.
    • (2001) Eur Respir J , vol.17 , pp. 337-342
    • Schols, A.M.1    Wesseling, G.2    Kester, A.D.3
  • 19
    • 0027962628 scopus 로고
    • Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study
    • Anthonisen NR, Connett JE, Kiley JP, et al. Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study. JAMA 1994; 272: 1497-1505.
    • (1994) JAMA , vol.272 , pp. 1497-1505
    • Anthonisen, N.R.1    Connett, J.E.2    Kiley, J.P.3
  • 20
    • 0036724894 scopus 로고    scopus 로고
    • Smoking and lung function of Lung Health Study participants after 11 years
    • Anthonisen NR, Connett JE, Murray RP. Smoking and lung function of Lung Health Study participants after 11 years. Am J Respir Crit Care Med 2002; 166: 675-679.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 675-679
    • Anthonisen, N.R.1    Connett, J.E.2    Murray, R.P.3
  • 21
    • 13444250953 scopus 로고    scopus 로고
    • The effects of a smoking cessation intervention on 14.5-year mortality: A randomized clinical trial
    • Anthonisen NR, Skeans MA, Wise RA, et al. The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial. Ann Intern Med 2005; 142: 233-239.
    • (2005) Ann Intern Med , vol.142 , pp. 233-239
    • Anthonisen, N.R.1    Skeans, M.A.2    Wise, R.A.3
  • 22
    • 0019460452 scopus 로고
    • Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Report of the Medical Research Council Working Party
    • Medical Research Council Working Party
    • Medical Research Council Working Party. Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Report of the Medical Research Council Working Party. Lancet 1981; 1: 681-686.
    • (1981) Lancet , vol.1 , pp. 681-686
  • 23
    • 0018885920 scopus 로고
    • Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease. A clinical trial
    • Nocturnal Oxygen Therapy Trial Group
    • Nocturnal Oxygen Therapy Trial Group. Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease. A clinical trial. Ann Intern Med 1980; 93: 391-398.
    • (1980) Ann Intern Med , vol.93 , pp. 391-398
  • 24
    • 0030774771 scopus 로고    scopus 로고
    • Effect of long-term oxygen therapy on survival in patients with chronic obstructive pulmonary disease with moderate hypoxaemia
    • Gorecka D, Gorzelak K, Sliwinski P, Tobiasz M, Zielinski J. Effect of long-term oxygen therapy on survival in patients with chronic obstructive pulmonary disease with moderate hypoxaemia. Thorax 1997; 52: 674-679.
    • (1997) Thorax , vol.52 , pp. 674-679
    • Gorecka, D.1    Gorzelak, K.2    Sliwinski, P.3    Tobiasz, M.4    Zielinski, J.5
  • 25
    • 0032693746 scopus 로고    scopus 로고
    • A randomized trial of nocturnal oxygen therapy in chronic obstructive pulmonary disease patients
    • Chaouat A, Weitzenblum E, Kessler R, et al. A randomized trial of nocturnal oxygen therapy in chronic obstructive pulmonary disease patients. Eur Respir J 1999; 14: 1002-1008.
    • (1999) Eur Respir J , vol.14 , pp. 1002-1008
    • Chaouat, A.1    Weitzenblum, E.2    Kessler, R.3
  • 26
    • 11844265905 scopus 로고    scopus 로고
    • One-year analysis of longitudinal changes in spirometry in patients with COPD receiving tiotropium
    • Anzueto A, Tashkin D, Menjoge S, Kesten S. One-year analysis of longitudinal changes in spirometry in patients with COPD receiving tiotropium. Pulm Pharmacol Ther 2005; 18: 75-81.
    • (2005) Pulm Pharmacol Ther , vol.18 , pp. 75-81
    • Anzueto, A.1    Tashkin, D.2    Menjoge, S.3    Kesten, S.4
  • 27
    • 33748791781 scopus 로고    scopus 로고
    • Pharmacotherapy for mortality reduction in chronic obstructive pulmonary disease
    • Sin DD, Man SF. Pharmacotherapy for mortality reduction in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006; 3: 624-629.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 624-629
    • Sin, D.D.1    Man, S.F.2
  • 28
    • 28244434375 scopus 로고    scopus 로고
    • Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease
    • Sin DD, Wu L, Anderson JA, et al. Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease. Thorax 2005; 60: 992-997.
    • (2005) Thorax , vol.60 , pp. 992-997
    • Sin, D.D.1    Wu, L.2    Anderson, J.A.3
  • 29
    • 0036798266 scopus 로고    scopus 로고
    • Survival in COPD patients after regular use of fluticasone propionate and salmeterol in general practice
    • Soriano JB, Vestbo J, Pride NB, Kiri V, Maden C, Maier WC. Survival in COPD patients after regular use of fluticasone propionate and salmeterol in general practice. Eur Respir J 2002; 20: 819-825.
    • (2002) Eur Respir J , vol.20 , pp. 819-825
    • Soriano, J.B.1    Vestbo, J.2    Pride, N.B.3    Kiri, V.4    Maden, C.5    Maier, W.C.6
  • 30
    • 33847172367 scopus 로고    scopus 로고
    • Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
    • Calverley PM, Anderson JA, Celli B, et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 2007; 356: 775-789.
    • (2007) N Engl J Med , vol.356 , pp. 775-789
    • Calverley, P.M.1    Anderson, J.A.2    Celli, B.3
  • 31
    • 85041540031 scopus 로고    scopus 로고
    • Effect of salmeterol/fluticasone propionate (SFC) on bone mineral density (BMD) and eye disorders over three years in the TORCH trial
    • Ferguson GT, Calverley PMA, Anderson JA, et al. Effect of salmeterol/fluticasone propionate (SFC) on bone mineral density (BMD) and eye disorders over three years in the TORCH trial. Am J Respir Crit Care Med 2007; 175: A763.
    • (2007) Am J Respir Crit Care Med , vol.175
    • Ferguson, G.T.1    Calverley, P.M.A.2    Anderson, J.A.3
  • 32
    • 33646356973 scopus 로고    scopus 로고
    • Evolving concepts in the measurement of treatment effects
    • Leidy NK. Evolving concepts in the measurement of treatment effects. Proc Am Thorac Soc 2006; 3: 212-217.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 212-217
    • Leidy, N.K.1
  • 33
    • 33646338189 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: Linking outcomes and pathobiology of disease modification
    • Rennard SI. Chronic obstructive pulmonary disease: linking outcomes and pathobiology of disease modification. Proc Am Thorac Soc 2006; 3: 276-280.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 276-280
    • Rennard, S.I.1
  • 34
    • 0042354673 scopus 로고    scopus 로고
    • Prednisolone response in patients with chronic obstructive pulmonary disease: Results from the ISOLDE study
    • Burge PS, Calverley PM, Jones PW, Spencer S, Anderson JA. Prednisolone response in patients with chronic obstructive pulmonary disease: results from the ISOLDE study. Thorax 2003; 58: 654-658.
    • (2003) Thorax , vol.58 , pp. 654-658
    • Burge, P.S.1    Calverley, P.M.2    Jones, P.W.3    Spencer, S.4    Anderson, J.A.5
  • 35
    • 0024332914 scopus 로고
    • The relationship between pulmonary function and dyspnea in obstructive lung disease
    • Wolkove N, Dajczman E, Colacone A, Kreisman H. The relationship between pulmonary function and dyspnea in obstructive lung disease. Chest 1989; 96: 1247-1251.
    • (1989) Chest , vol.96 , pp. 1247-1251
    • Wolkove, N.1    Dajczman, E.2    Colacone, A.3    Kreisman, H.4
  • 36
    • 0033925684 scopus 로고    scopus 로고
    • Factor analysis of changes in dyspnea and lung function parameters after bronchodilation in chronic obstructive pulmonary disease
    • Taube C, Lehnigk B, Paasch K, Kirsten DK, Jorres RA, Magnussen H. Factor analysis of changes in dyspnea and lung function parameters after bronchodilation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000; 162: 216-220.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 216-220
    • Taube, C.1    Lehnigk, B.2    Paasch, K.3    Kirsten, D.K.4    Jorres, R.A.5    Magnussen, H.6
  • 37
    • 17444447481 scopus 로고    scopus 로고
    • Does inhaled albuterol improve diaphragmatic contractility in patients with chronic obstructive pulmonary disease?
    • Hatipoglu U, Laghi F, Tobin MJ. Does inhaled albuterol improve diaphragmatic contractility in patients with chronic obstructive pulmonary disease? Am J Respir Crit Care Med 1999; 160: 1916-1921.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1916-1921
    • Hatipoglu, U.1    Laghi, F.2    Tobin, M.J.3
  • 38
    • 33646565124 scopus 로고    scopus 로고
    • Outcomes and markers in the assessment of chronic obstructive pulmonary disease
    • Jones PW, Agusti AG. Outcomes and markers in the assessment of chronic obstructive pulmonary disease. Eur Respir J 2006; 27: 822-832.
    • (2006) Eur Respir J , vol.27 , pp. 822-832
    • Jones, P.W.1    Agusti, A.G.2
  • 39
    • 0036181956 scopus 로고    scopus 로고
    • A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease
    • Casaburi R, Mahler DA, Jones PW, et al. A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease. Eur Respir J 2002; 19: 217-224.
    • (2002) Eur Respir J , vol.19 , pp. 217-224
    • Casaburi, R.1    Mahler, D.A.2    Jones, P.W.3
  • 40
    • 0034643610 scopus 로고    scopus 로고
    • Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: The ISOLDE trial
    • Burge PS, Calverley PM, Jones PW, Spencer S, Anderson JA, Maslen TK. Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial. BMJ 2000; 320: 1297-1303.
    • (2000) BMJ , vol.320 , pp. 1297-1303
    • Burge, P.S.1    Calverley, P.M.2    Jones, P.W.3    Spencer, S.4    Anderson, J.A.5    Maslen, T.K.6
  • 41
    • 0036153433 scopus 로고    scopus 로고
    • Scientific rationale for inhaled combination therapy with long-acting beta2-agonists and corticosteroids
    • Barnes PJ. Scientific rationale for inhaled combination therapy with long-acting beta2-agonists and corticosteroids. Eur Respir J 2002; 19: 182-191.
    • (2002) Eur Respir J , vol.19 , pp. 182-191
    • Barnes, P.J.1
  • 42
    • 0037425745 scopus 로고    scopus 로고
    • Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: A randomised controlled trial
    • Calverley P, Pauwels R, Vestbo J, et al. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2003; 361: 449-456.
    • (2003) Lancet , vol.361 , pp. 449-456
    • Calverley, P.1    Pauwels, R.2    Vestbo, J.3
  • 43
    • 0037246566 scopus 로고    scopus 로고
    • Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease
    • Szafranski W, Cukier A, Ramirez A, et al. Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease. Eur Respir J 2003; 21: 74-81.
    • (2003) Eur Respir J , vol.21 , pp. 74-81
    • Szafranski, W.1    Cukier, A.2    Ramirez, A.3
  • 44
    • 0347473812 scopus 로고    scopus 로고
    • Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease
    • Calverley PM, Boonsawat W, Cseke Z, Zhong N, Peterson S, Olsson H. Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease. Eur Respir J 2003; 22: 912-919.
    • (2003) Eur Respir J , vol.22 , pp. 912-919
    • Calverley, P.M.1    Boonsawat, W.2    Cseke, Z.3    Zhong, N.4    Peterson, S.5    Olsson, H.6
  • 45
    • 33144476873 scopus 로고    scopus 로고
    • The Salmeterol Multicenter Asthma Research Trial: A comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol
    • Nelson HS, Weiss ST, Bleecker ER, et al. The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest 2006; 129: 15-26.
    • (2006) Chest , vol.129 , pp. 15-26
    • Nelson, H.S.1    Weiss, S.T.2    Bleecker, E.R.3
  • 47
    • 37249075362 scopus 로고    scopus 로고
    • Future options for disease intervention: Important advances in phosphodiesterase 4 inhibitors
    • McIvor RA. Future options for disease intervention: important advances in phosphodiesterase 4 inhibitors. Eur Respir Rev 2007; 16: 105-112.
    • (2007) Eur Respir Rev , vol.16 , pp. 105-112
    • McIvor, R.A.1
  • 48
    • 20444480168 scopus 로고    scopus 로고
    • COPD: Current therapeutic interventions and future approaches
    • Barnes PJ, Stockley RA. COPD: current therapeutic interventions and future approaches. Eur Respir J 2005; 25: 1084-1106.
    • (2005) Eur Respir J , vol.25 , pp. 1084-1106
    • Barnes, P.J.1    Stockley, R.A.2
  • 49
    • 4444280869 scopus 로고    scopus 로고
    • Prospects for new drugs for chronic obstructive pulmonary disease
    • Barnes PJ, Hansel TT. Prospects for new drugs for chronic obstructive pulmonary disease. Lancet 2004; 364: 985-996.
    • (2004) Lancet , vol.364 , pp. 985-996
    • Barnes, P.J.1    Hansel, T.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.