Human cytomegalovirus (HCMV) and hearing impairment: Infection of fibroblast cells with HCMV induces chromosome breaks at 1q23.3, between loci DFNA7 and DFNA49-Both involved in dominantly inherited, sensorineural, hearing impairment

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 637, Issue 1-2, 2008, Pages 56-65

  Nystad, Mona ^a   Fagerheim, Toril ^a   Brox, Vigdis ^a   Fortunato, Elizabeth A ^b   Nilssen, Øivind ^a,c  

^a UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^b UNIVERSITY OF IDAHO   (United States)

^c UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Chromosome break; Chromosome gap; Cytomegalovirus; DFNA49; DFNA7; HCMV; Hearing impairment; MPZ

Indexed keywords

GENE PRODUCT; PROTEIN DFNA49; PROTEIN DFNA7; UNCLASSIFIED DRUG;

ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BLOOD ANALYSIS; CELL CYCLE S PHASE; CHROMOSOME 1Q; CHROMOSOME BREAKAGE; CONGENITAL INFECTION; CYTOLYSIS; DEVELOPED COUNTRY; DISEASE ASSOCIATION; FIBROBLAST; GENE LOCUS; GENETIC DAMAGE; HEARING IMPAIRMENT; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HUMAN CYTOMEGALOVIRUS; PERCEPTION DEAFNESS; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; VESTIBULOCOCHLEAR NERVE DISEASE; VIRUS LOAD; VIRUS REPLICATION;

CHROMOSOME BREAKAGE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 1; CYTOMEGALOVIRUS INFECTIONS; FIBROBLASTS; HEARING; HEARING LOSS, SENSORINEURAL; HUMANS; MODELS, GENETIC; REPETITIVE SEQUENCES, NUCLEIC ACID;

CYTOMEGALOVIRUS; HUMAN HERPESVIRUS 5;

EID: 37149052158     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2007.07.009     Document Type: Article

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