DNA strand-scission by phloroglucinols and lignans from heartwood of Garcinia subelliptica Merr. and Justicia plants

Phytochemistry

Volumn 69, Issue 1, 2008, Pages 225-233

  Lu, Yi Huang ^a   Wei, Bai Luh ^b   Ko, Horng Huey ^a   Lin, Chun Nan ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAITUNG UNIVERSITY   (Taiwan)

Author keywords

Acanthaceae; DNA strand scission activity; Garcinia subelliptica; Guttiferae; Heartwood; Justicia; Lignan; Phloroglucinol

Indexed keywords

2,9 DIMETHYL 1,10 PHENANTHROLINE; CIRCULAR DNA; COPPER; LIGNAN; PHENANTHROLINE DERIVATIVE; PHLOROGLUCINOL; REACTIVE OXYGEN METABOLITE;

ACANTHACEAE; AGAR GEL ELECTROPHORESIS; ARTICLE; CHEMISTRY; DNA CLEAVAGE; DNA DAMAGE; DNA SUPERCOILING; DRUG EFFECT; GARCINIA; INFRARED SPECTROPHOTOMETRY; ISOLATION AND PURIFICATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; WOOD;

ACANTHACEAE; COPPER; DNA CLEAVAGE; DNA DAMAGE; DNA, CIRCULAR; DNA, SUPERHELICAL; ELECTROPHORESIS, AGAR GEL; GARCINIA; LIGNANS; MAGNETIC RESONANCE SPECTROSCOPY; PHENANTHROLINES; PHLOROGLUCINOL; REACTIVE OXYGEN SPECIES; SPECTROPHOTOMETRY, INFRARED; WOOD;

ACANTHACEAE; CILIOPHORA; CLUSIACEAE; GARCINIA; GARCINIA SUBELLIPTICA; JUSTICIA; JUSTICIA CILIATA; JUSTICIA PROCUMBENS;

EID: 37149025347     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2007.06.026     Document Type: Article

References (26)

1. Ahsan H., and Hadi S.M. Strand scission in DNA induced by curcumin in the presence of Cu(II). Cancer Lett. 124 (1998) 23-30
2. Bellamy L.J. The Infra-red Spectra of Complex Molecules. 2nd ed. (1958), Methuen & Co. Ltd., London p. 132
3. Cahill D.M., and Shannon P.V.R. Mild oxidative cyclisation of an isopentenyl side-chain. J. Chem. Soc. C (1969) 938-942
4. Chaudhuri S.K., Huang L., Fullas F., Brown D.M., Wani M.C., and Wall M.E. Isolation and structure identification of an active DNA strand-scission agent, (+)-3,4-dihydroxy-8,9-methylenedioxypterocarpan. J. Nat. Prod. 58 (1995) 1966-1969
5. Chung M.-I., Su H.-J., and Lin C.-N. A novel triterpenoid of Garcinia subelliptica. J. Nat. Prod. 61 (1998) 1015-1016
6. Day S.-H., Lin Y.-C., Tsai M.-L., Tsao L.-T., Ko H.-H., Chung M.-I., Lee J.-C., Wang J.-P., Won S.-J., and Lin C.-N. Potent cytotoxic lignans from Justicia procumbens and their effects on nitric oxide and tumor necrosis factor-α production in mouse macrophages. J. Nat. Prod. 65 (2002) 379-381
7. Day S.-H., Chiu N.-Y., Tsao L.-T., Wang J.-P., and Lin C.-N. New lignan glycosides with potent anti-inflammatory effect, isolated from Justicia ciliata. J. Nat. Prod. 63 (2000) 1560-1562
8. Day S.-H., Chiu N.-Y., Won S.-J., and Lin C.-N. Cytotoxic lignans of Justicia ciliata. J. Nat. Prod. 62 (1999) 1056-1058
9. Furukawa A., Oikawa S., Murata M., Hiraku Y., and Kawanishi S. Epigallocatechin gallate causes oxidative damage to isolated and cellular DNA. Biochem. Pharmacol. 66 (2003) 1769-1778
10. Fukuyama Y., Kaneshi A., Tani N., and Kodama M. Subellinone, a polyisoprenylated phloroglucinol derivative from Garcinia subelliptica. Phytochemistry 33 (1993) 483-485
11. Fukuyama Y., Minami H., and Kuwayama A. Garsubellins, polyisoprenylated phloroglucinol derivatives from Garcinia subelliptica. Phytochemistry 49 (1998) 853-857
12. Iinuma M., Tosa H., Tanaka T., Asai F., and Shimano R. Two xanthones with a 1,1-dimethylallyl group in root bark of Garcinia subelliptica. Phytochemistry 39 (1995) 945-947
13. Lee J.-C., Lee C.-H., Su C.-L., Hung C.-W., Liu H.-S., Lin C.-N., and Won S.-J. Justicidin A decreases the level of cytosolic ku70 leading to apoptosis in human colorectal cancer cells. Carcinogensis 20 (2005) 1716-1730
14. Lin C.-N., Kiang C.-W., Lu C.-M., Wu R.-R., and Lee K.-H. Garcinielliptin oxide, a triterpenoid with a novel skeleton, isolated from Garcinia subelliptica. J. Chem. Soc. Chem. Commun. (1996) 1315-1316
15. Minami H., Kinoshita M., Fukuyama Y., Kodama M., Yoshizawa T., Sugiura M., Nakagawa K., and Tago H. Antioxidant xanthones from Garcinia subelliptica. Phytochemistry 36 (1994) 501-506
16. Minami H., Takahashi E., Kodama M., and Fukuyama Y. Three xanthones from Garcinia subelliptica. Phytochemistry 41 (1996) 629-633
17. Minami H., Hamaguchi K., Kubo M., and Fukuyama Y. A benzophenone and a xanthone from Garcinia subelliptica. Phytochemistry 49 (1998) 1783-1785
18. Scatt A.I. Interpretation of the Ultraviolet Spectra of Natural Products (1964), Pergamon, New York pp. 58, 102
19. Su C.-L., Hung L.-L.-H., Huang L.-M., Lee J.-C., Lin C.-N., and Won S.-J. Caspase-8 acts a key upstream executor of mitochondria during justicidin A induced apoptosis in human hepatoma cells. FEBS Lett. 580 (2006) 3185-3191
20. Tosa H., Iinuma M., Tanaka T., Nozaki H., Ikeda S., Tsutsui K., Yanada M., and Fujimori S. Inhibitory activity of xanthones derivatives isolated from some Guttiferaeous plants against DNA topoisomerases I and II. Chem. Pharm. Bull. 45 (1997) 418-420
21. Weng J.-R., Lin C.-N., Tsao L.-T., and Wang J.-P. Terpenoids with a new skeleton and novel triterpenoids with anti-inflammatory effect from Garcinia subelliptica. Chem. Eur. J. 9 (2003) 5520-5527
22. Weng J.R., Tsao L.T., Wang J.P., and Lin C.N. Novel and anti-inflammatory constituents of Garcinia subelliptica. Chem. Eur. J. 9 (2003) 1958-1963
23. Weng J.-R., Tsao L.-T., Wang J.-P., Wu R.-R., and Lin C.-N. Anti-inflammatory phloroglucinols and terpenoids from Garcinia subelliptica. J. Nat. Prod. 67 (2004) 1796-1799
24. Wu C.-C., Weng J.-R., Won S.-J., and Lin C.-N. Constituents of the pericarp of Garcinia subelliptica. J. Nat. Prod. 68 (2005) 1125-1127
25. Zhao F., Hozawa H., Daikonnya A., Kondo K., and Kitanaka S. Inhibitors of nitric oxide production from Hop (Humulus lupulus L.). Biol. Pharm. Bull. 26 (2003) 61-65
26. Zhao F., Watanabe Y., Nozawa H., Daihonnya A., Kondo K., and Kitanaka S. Prenylflavonoids and phloroglucinol derivatives from Hops (Humulus lupulus). J. Nat. Prod. 68 (2005) 43-49