Donor Brain Death Mechanisms and Outcomes After Heart Transplantation

Transplantation Proceedings

Volumn 39, Issue 10, 2007, Pages 2964-2969

  Cohen, O ^a   De La Zerda, D J ^a   Beygui, R ^a   Hekmat, D ^a   Laks, H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANOXIA; ARTICLE; BLUNT TRAUMA; BRAIN DEATH; BRAIN INFECTION; BRAIN TUMOR; CADAVER DONOR; CAUSE OF DEATH; CEREBROVASCULAR DISEASE; FEMALE; GRAFT REJECTION; HEAD INJURY; HEART TRANSPLANTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PENETRATING TRAUMA; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SURVIVAL RATE; UNITED STATES; URBAN AREA;

ADULT; BRAIN DEATH; FEMALE; GRAFT REJECTION; HEART TRANSPLANTATION; HEART-LUNG TRANSPLANTATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; SURVIVAL RATE; TISSUE DONORS; TREATMENT OUTCOME;

EID: 37049037700     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2007.08.102     Document Type: Article

References (24)

1. Taylor D.O., Edwards L.B., Mohacsi P.J., et al. The registry of the International Society for Heart and Lung Transplantation: twentieth official adult heart transplant report-2003. J Heart Lung Transplant 22 (2003) 16
2. Marelli D., Laks H., Bresson J., et al. Sixteen-year experience with 1,000 heart transplants at UCLA. Clin Transpl X (2000) 297
3. Tsai F.C., Marelli D., Bresson J., et al. Use of hearts transplanted from donors with atraumatic intracranial bleeds. J Heart Lung Transplant 21 (2002) 623
4. McCarthy J.F., McCarthy P.M., Massad M.G., et al. Risk factors for death after heart transplantation: Does a single-center experience correlate with multicenter registries?. Ann Thorac Surg 65 (1998) 1574
5. Busson M., N'Doye P., Benoit G., et al. Donor factors influencing organ transplant prognosis. Transplant Proc 27 (1995) 1662
6. Mehra M.R., Uber P.A., Ventura H.O., et al. The impact of mode of donor brain death on cardiac allograft vasculopathy: an intravascular ultrasound study. J Am Coll Cardiol 43 (2004) 806
7. Wilhelm M.J., Pratschke J., Beato F., et al. Activation of the heart by donor brain death accelerates acute rejection after transplantation. Circulation 102 (2000) 2426
8. Wilhelm M.J., Pratschke J., Laskowski I.A., et al. Brain death and its impact on the donor heart-lessons from animal models. J Heart Lung Transplant 19 (2000) 414
9. Shivalkar B., Van Loon J., Wieland W., et al. Variable effects of explosive or gradual increase of intracranial pressure on myocardial structure and function. Circulation 87 (1993) 230
10. Baroldi G., Di Pasquale G., Silver M.D., et al. Type and extent of myocardial injury related to brain damage and its significance in heart transplantation: a morphometric study. J Heart Lung Transplant 16 (1997) 994
11. Van Loon J., Shivalkar B., Plets C., et al. Catecholamine response to a gradual increase of intracranial pressure. J Neurosurg 79 (1993) 705
12. Pratschke J., Wilhelm M.J., Kusaka M., et al. Brain death and its influence on donor organ quality and outcome after transplantation. Transplantation 67 (1999) 343
13. Goel R., Johnson F., and Mehra M.R. Brain injury and ventricular dysfunction: insights into reversible heart failure. Congest Heart Fail 11 (2005) 99
14. Plenz G., Eschert H., Erren M., et al. The interleukin-6/interleukin-6-receptor system is activated in donor hearts. J Am Coll Cardiol 39 (2002) 1508
15. Marelli D., Laks H., Kobashigawa J.A., et al. Seventeen-year experience with 1,083 heart transplants at a single institution. Ann Thorac Surg 74 (2002) 1558
16. Billingham M.E., Cary N.R., Hammond M.E., et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart rejection study group. The International Society for Heart Transplantation. J Heart Lung Transplant 9 (1990) 587
17. Billingham M., and Kobashigawa J.A. The revised ISHLT heart biopsy grading scale. J Heart Lung Transplant 24 (2005) 1709
18. Takada M., Nadeau K., Hancock W., et al. Effects of explosive brain death on cytokine activation of peripheral organs in the rat. Transplantation 65 (1998) 1533
19. Powner D., Hendrich A., Nyhuis A., et al. Changes in serum catecholamine levels in patients who are brain dead. J Heart Lung Transplant 11 (1992) 1046
20. Ciccone A., Stewart K., Meyers B., et al. Does donor cause of death affect the outcome of lung transplantation?. J Thorac Cardiovasc Surg 123 (2002) 429
21. Wahlers T., Cremer J., Fieguth H.G., et al. Donor heart related variables and early mortality after heart transplantation. J Heart Lung Transplant 10 (1991) 22
22. Anyanwu A.C., Banner N.R., Mitchell A.G., et al. Low incidence and severity of transplant-associated coronary artery disease in heart transplants from live donors. J Heart Lung Transplant 22 (2003) 281
23. Novitzky D., Rose A.G., and Cooper D.K. Injury of myocardial conduction tissue and coronary artery smooth muscle following brain death in the baboon. Transplantation 45 (1988) 964
24. Birks E.J., Yacoub M.H., Burton P.S., et al. Activation of apoptotic and inflammatory pathways in dysfunctional donor hearts. Transplantation 70 (2000) 1498