Mechanisms of the vasorelaxant effect of 1, 5-dihydroxy-2, 3-dimethoxy-xanthone, an active metabolite of 1-hydroxy-2, 3, 5-trimethoxy-xanthone isolated from a Tibetan herb, Halenia elliptica, on rat coronary artery

Life Sciences

Volumn 82, Issue 1-2, 2008, Pages 91-98

  Wang, Yan ^a,b   Shi, Jian Gong ^b   Wang, Mu Zou ^b   Che, Chun Tao ^a   Yeung, John H K ^c  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b INSTITUTE OF MATERIA MEDICA   (China)

^c and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

1; 1 Hydroxy 2; 3, 5 trimethoxy xanthone; 5 Dihydroxy 2, 3 dimethoxy xanthone; Active metabolite; Halenia elliptica; Vasorelaxation

Indexed keywords

1 HYDROXY 2,3,5 TRIMETHOXYXANTHONE; 1,5 DIHYDROXY 2,3 DIMETHOXYXANTHONE; 1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 AMINOPYRIDINE; 9 (TETRAHYDRO 2 FURYL)ADENINE; BARIUM CHLORIDE; CALCIUM CHANNEL; CALCIUM CHLORIDE; DRUG METABOLITE; GLIBENCLAMIDE; HM 1; HM 5; IBERIOTOXIN; N(G) NITROARGININE METHYL ESTER; NIFEDIPINE; NITRIC OXIDE SYNTHASE; PHORBOL DIACETATE; SEROTONIN; TETRYLAMMONIUM; UNCLASSIFIED DRUG; VASODILATOR AGENT; XANTHONE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY; DRUG STRUCTURE; HALENIA ELLIPTICA; HERB; NONHUMAN; RAT; SMOOTH MUSCLE RELAXATION; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CORONARY VESSELS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENTIANACEAE; MALE; MEDICINE, TIBETAN TRADITIONAL; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; VASOCONSTRICTOR AGENTS; VASODILATION; XANTHONES;

HALENIA ELLIPTICA; RATTUS;

EID: 37049034715     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.10.014     Document Type: Article

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