메뉴 건너뛰기




Volumn 40, Issue 1, 2008, Pages 22-31

Novel therapeutic options in the inflammatory bowel disease world

Author keywords

Biologics; Children; Crohn's disease; Helminthes; Inflammatory bowel disease; Leukocyte apheresis; Probiotics; Stem cell transplantation; Ulcerative colitis

Indexed keywords

ABT 874; ADALIMUMAB; ALICAFORSEN; ANTIHISTAMINIC AGENT; ATLIZUMAB; BASILIXIMAB; CERTOLIZUMAB PEGOL; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DACLIZUMAB; DEXTRO ARGINYL DEXTRO NORLEUCYL DEXTRO NORLEUCYL DEXTRO NORLEUCYL DEXTRO ARGINYL DEXTRO NORLEUCYL DEXTRO NORLEUCYL DEXTRO NORLEUCYLGLYCYL DEXTRO TYROSINAMIDE; DRUG ANTIBODY; ETANERCEPT; FONTOLIZUMAB; INFLIXIMAB; MESALAZINE; METHOTREXATE; MLN 02; NATALIZUMAB; ONERCEPT; PLACEBO; PREDNISONE; PROBIOTIC AGENT; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 10; TETOMILAST; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNINDEXED DRUG; VISILIZUMAB;

EID: 37049033316     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dld.2007.07.169     Document Type: Short Survey
Times cited : (8)

References (81)
  • 1
    • 32044451548 scopus 로고    scopus 로고
    • Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial
    • Hanauer S.B., Sandborn W.J., Rutgeerts P., Fedorak R.N., Lukas M., MacIntosh D., et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology 130 (2006) 323-333
    • (2006) Gastroenterology , vol.130 , pp. 323-333
    • Hanauer, S.B.1    Sandborn, W.J.2    Rutgeerts, P.3    Fedorak, R.N.4    Lukas, M.5    MacIntosh, D.6
  • 2
    • 34249281002 scopus 로고    scopus 로고
    • Adalimumab for maintenance treatment of Crohn's disease: Results of the CLASSIC II trial
    • Sandborn W.J., Hanauer S.B., Rutgeerts P.J., Fedorak R.N., Lukas M., Macintosh D.G., et al. Adalimumab for maintenance treatment of Crohn's disease: Results of the CLASSIC II trial. Gut 56 (2007) 1232-1239
    • (2007) Gut , vol.56 , pp. 1232-1239
    • Sandborn, W.J.1    Hanauer, S.B.2    Rutgeerts, P.J.3    Fedorak, R.N.4    Lukas, M.5    Macintosh, D.G.6
  • 3
    • 33846242958 scopus 로고    scopus 로고
    • Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial
    • Colombel J.F., Sandborn W.J., Rutgeerts P., Enns R., Hanauer S.B., Panaccione R., et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial. Gastroenterology 132 (2007) 52-65
    • (2007) Gastroenterology , vol.132 , pp. 52-65
    • Colombel, J.F.1    Sandborn, W.J.2    Rutgeerts, P.3    Enns, R.4    Hanauer, S.B.5    Panaccione, R.6
  • 4
    • 34347402306 scopus 로고    scopus 로고
    • Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trial
    • Sandborn W.J., Rutgeerts P., Enns R., Hanauer S.B., Colombel J.F., Panaccione R., et al. Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trial. Ann Intern Med 146 (2007) 829-838
    • (2007) Ann Intern Med , vol.146 , pp. 829-838
    • Sandborn, W.J.1    Rutgeerts, P.2    Enns, R.3    Hanauer, S.B.4    Colombel, J.F.5    Panaccione, R.6
  • 5
    • 24644445063 scopus 로고    scopus 로고
    • Adalimumab, a novel anti-tumor necrosis factor-alpha antibody in a child with refractory Crohn's disease
    • Mian S., and Baron H. Adalimumab, a novel anti-tumor necrosis factor-alpha antibody in a child with refractory Crohn's disease. J Pediatr Gastroenterol Nutr 41 (2005) 357-359
    • (2005) J Pediatr Gastroenterol Nutr , vol.41 , pp. 357-359
    • Mian, S.1    Baron, H.2
  • 6
    • 34247236173 scopus 로고    scopus 로고
    • Open label experience with adalimumab in pediatric Crohn's disease patients who lost response or were intolerant to infliximab
    • A-656
    • Deslandres C., Faure C., Dirks M., Gervais F., Seidman E., and Seidman E.G. Open label experience with adalimumab in pediatric Crohn's disease patients who lost response or were intolerant to infliximab. Gastroenterology 130, S2 (2006) A-656
    • (2006) Gastroenterology , vol.130 S2
    • Deslandres, C.1    Faure, C.2    Dirks, M.3    Gervais, F.4    Seidman, E.5    Seidman, E.G.6
  • 7
    • 34249857135 scopus 로고    scopus 로고
    • Adalimumab induction therapy for ulcerative colitis with intolerance or lost response to infliximab: An open-label study
    • Peyrin-Biroulet L., Laclotte C., Roblin X., and Bigard M.A. Adalimumab induction therapy for ulcerative colitis with intolerance or lost response to infliximab: An open-label study. World J Gastroenterol 13 (2007) 2328-2332
    • (2007) World J Gastroenterol , vol.13 , pp. 2328-2332
    • Peyrin-Biroulet, L.1    Laclotte, C.2    Roblin, X.3    Bigard, M.A.4
  • 9
    • 0031043778 scopus 로고    scopus 로고
    • Randomised controlled trial of CDP571 antibody to tumour necrosis factor-alpha in Crohn's disease
    • Stack W.A., Mann S.D., Roy A.J., Heath P., Sopwith M., Freeman J., et al. Randomised controlled trial of CDP571 antibody to tumour necrosis factor-alpha in Crohn's disease. Lancet 349 (1997) 521-524
    • (1997) Lancet , vol.349 , pp. 521-524
    • Stack, W.A.1    Mann, S.D.2    Roy, A.J.3    Heath, P.4    Sopwith, M.5    Freeman, J.6
  • 10
    • 0035053968 scopus 로고    scopus 로고
    • An engineered human antibody to TNF (CDP571) for active Crohn's disease: a randomized double-blind placebo-controlled trial
    • Sandborn W.J., Feagan B.G., Hanauer S.B., Present D.H., Sutherland L.R., Kamm M.A., et al. An engineered human antibody to TNF (CDP571) for active Crohn's disease: a randomized double-blind placebo-controlled trial. Gastroenterology 120 (2001) 1330-1338
    • (2001) Gastroenterology , vol.120 , pp. 1330-1338
    • Sandborn, W.J.1    Feagan, B.G.2    Hanauer, S.B.3    Present, D.H.4    Sutherland, L.R.5    Kamm, M.A.6
  • 11
    • 4644325814 scopus 로고    scopus 로고
    • CDP571, a humanised monoclonal antibody to tumour necrosis factor alpha, for moderate to severe Crohn's disease: a randomised, double blind, placebo controlled trial
    • Sandborn W.J., Feagan B.G., Radford-Smith G., Kovacs A., Enns R., Innes A., et al. CDP571, a humanised monoclonal antibody to tumour necrosis factor alpha, for moderate to severe Crohn's disease: a randomised, double blind, placebo controlled trial. Gut 53 (2004) 1485-1493
    • (2004) Gut , vol.53 , pp. 1485-1493
    • Sandborn, W.J.1    Feagan, B.G.2    Radford-Smith, G.3    Kovacs, A.4    Enns, R.5    Innes, A.6
  • 12
    • 20044382590 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, in patients with corticosteroid-dependent Crohn's disease
    • Feagan B.G., Sandborn W.J., Baker J.P., Cominelli F., Sutherland L.R., Elson C.O., et al. A randomized, double-blind, placebo-controlled trial of CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, in patients with corticosteroid-dependent Crohn's disease. Aliment Pharmacol Ther 21 (2005) 373-384
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 373-384
    • Feagan, B.G.1    Sandborn, W.J.2    Baker, J.P.3    Cominelli, F.4    Sutherland, L.R.5    Elson, C.O.6
  • 13
    • 33644999128 scopus 로고    scopus 로고
    • CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, for steroid-dependent Crohn's disease: a randomized, double-blind, placebo-controlled trial
    • Feagan B.G., Sandborn W.J., Lichtenstein G., Radford-Smith G., Patel J., Innes A., et al. CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, for steroid-dependent Crohn's disease: a randomized, double-blind, placebo-controlled trial. Aliment Pharmacol Ther 23 (2006) 617-628
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 617-628
    • Feagan, B.G.1    Sandborn, W.J.2    Lichtenstein, G.3    Radford-Smith, G.4    Patel, J.5    Innes, A.6
  • 14
    • 11144318616 scopus 로고    scopus 로고
    • Intravenous CDP870, a PEGylated Fab' fragment of a humanized antitumour necrosis factor antibody, in patients with moderate-to-severe Crohn's disease: an exploratory study
    • Winter T.A., Wright J., Ghosh S., Jahnsen J., Innes A., Round P., et al. Intravenous CDP870, a PEGylated Fab' fragment of a humanized antitumour necrosis factor antibody, in patients with moderate-to-severe Crohn's disease: an exploratory study. Aliment Pharmacol & Ther 20 (2004) 1337-1346
    • (2004) Aliment Pharmacol & Ther , vol.20 , pp. 1337-1346
    • Winter, T.A.1    Wright, J.2    Ghosh, S.3    Jahnsen, J.4    Innes, A.5    Round, P.6
  • 15
    • 24144483087 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease
    • Schreiber S., Rutgeerts P., Fedorak R.N., Khaliq-Kareemi M., Kamm M.A., Boivin M., et al. A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease. Gastroenterology 129 (2005) 807-818
    • (2005) Gastroenterology , vol.129 , pp. 807-818
    • Schreiber, S.1    Rutgeerts, P.2    Fedorak, R.N.3    Khaliq-Kareemi, M.4    Kamm, M.A.5    Boivin, M.6
  • 16
    • 33748923591 scopus 로고    scopus 로고
    • Certolizumab pegol administered subcutaneously is effective and well tolerated in patients with active Crohn's disease: results from a 26-week, placebo-controlled Pase III study (PRECiSE 1)
    • A-9
    • Sandborn W.J.F., Feagan B.G., Stoinov S., Honiball P.J., Rutgeerts P., McColm J.A., et al. Certolizumab pegol administered subcutaneously is effective and well tolerated in patients with active Crohn's disease: results from a 26-week, placebo-controlled Pase III study (PRECiSE 1). Gastroenterology 130 (2006, S2) A-9
    • (2006) Gastroenterology , vol.130
    • Sandborn, W.J.F.1    Feagan, B.G.2    Stoinov, S.3    Honiball, P.J.4    Rutgeerts, P.5    McColm, J.A.6
  • 17
    • 37048999707 scopus 로고    scopus 로고
    • Schreiber SF, Hanauer SB, Lichtenstein GR, Sandborn WJ. Superior efficacy of certolizumab pegol in early Crohn's disease is independent of CRP status. AGA abstract 2007.
  • 18
    • 37049008437 scopus 로고    scopus 로고
    • Colombel JF, Schreiber SF, Hanauer SB, Rutgeerts P, Sandborn WJ. Long-term tolerability of subcutaneous certolizumab pegol in active Crohn's disease: results from PRECiSE 3 and 4. AGA abstract 2007.
  • 19
    • 9144261186 scopus 로고    scopus 로고
    • CDP571, a humanized anti-tumor necrosis factor-alpha monoclonal antibody in pediatric Crohn's disease
    • Mamula P., Cohen S.A., Ferry G.D., Kirschner B.S., Winter H.S., Innes A., et al. CDP571, a humanized anti-tumor necrosis factor-alpha monoclonal antibody in pediatric Crohn's disease. Inflamm Bowel Dis 10 (2004) 723-730
    • (2004) Inflamm Bowel Dis , vol.10 , pp. 723-730
    • Mamula, P.1    Cohen, S.A.2    Ferry, G.D.3    Kirschner, B.S.4    Winter, H.S.5    Innes, A.6
  • 21
    • 0034754477 scopus 로고    scopus 로고
    • Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial
    • Sandborn W.J., Hanauer S.B., Katz S., Safdi M., Wolf D.G., Baerg R.D., et al. Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial. Gastroenterology 121 (2001) 1088-1094
    • (2001) Gastroenterology , vol.121 , pp. 1088-1094
    • Sandborn, W.J.1    Hanauer, S.B.2    Katz, S.3    Safdi, M.4    Wolf, D.G.5    Baerg, R.D.6
  • 23
    • 0034903450 scopus 로고    scopus 로고
    • A randomized placebo-controlled trial of a humanized monoclonal antibody to alpha4 integrin in active Crohn's disease
    • Gordon F.H., Lai C.W., Hamilton M.I., Allison M.C., Srivastava E.D., Fouweather M.G., et al. A randomized placebo-controlled trial of a humanized monoclonal antibody to alpha4 integrin in active Crohn's disease. Gastroenterology 121 (2001) 268-274
    • (2001) Gastroenterology , vol.121 , pp. 268-274
    • Gordon, F.H.1    Lai, C.W.2    Hamilton, M.I.3    Allison, M.C.4    Srivastava, E.D.5    Fouweather, M.G.6
  • 27
    • 33846184129 scopus 로고    scopus 로고
    • Safety and tolerability of concurrent natalizumab treatment for patients with Crohn's disease not in remission while receiving infliximab
    • Sands B.E., Kozarek R., Spainhour J., Barish C.F., Becker S., Goldberg L., et al. Safety and tolerability of concurrent natalizumab treatment for patients with Crohn's disease not in remission while receiving infliximab. Inflamm Bowel Dis 13 (2007) 2-11
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 2-11
    • Sands, B.E.1    Kozarek, R.2    Spainhour, J.3    Barish, C.F.4    Becker, S.5    Goldberg, L.6
  • 29
    • 0036110371 scopus 로고    scopus 로고
    • A pilot study of treatment of active ulcerative colitis with natalizumab, a humanized monoclonal antibody to alpha-4 integrin
    • Gordon F.H., Hamilton M.I., Donoghue S., Greenlees C., Palmer T., Rowley-Jones D., et al. A pilot study of treatment of active ulcerative colitis with natalizumab, a humanized monoclonal antibody to alpha-4 integrin. Aliment Pharmacol Ther 16 (2002) 699-705
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 699-705
    • Gordon, F.H.1    Hamilton, M.I.2    Donoghue, S.3    Greenlees, C.4    Palmer, T.5    Rowley-Jones, D.6
  • 30
    • 33644605483 scopus 로고    scopus 로고
    • Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy
    • Yousry T.A., Major E.O., Ryschkewitsch C., Fahle G., Fischer S., Hou J., et al. Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy. N Engl J Med. 354 (2006) 924-933
    • (2006) N Engl J Med. , vol.354 , pp. 924-933
    • Yousry, T.A.1    Major, E.O.2    Ryschkewitsch, C.3    Fahle, G.4    Fischer, S.5    Hou, J.6
  • 32
    • 20444469332 scopus 로고    scopus 로고
    • Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin
    • Feagan B.G., Greenberg G.R., Wild G., Fedorak R.N., Paré P., McDonald J.W., et al. Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin. N Engl J Med 352 (2005) 2499-2507
    • (2005) N Engl J Med , vol.352 , pp. 2499-2507
    • Feagan, B.G.1    Greenberg, G.R.2    Wild, G.3    Fedorak, R.N.4    Paré, P.5    McDonald, J.W.6
  • 33
  • 34
    • 0036288638 scopus 로고    scopus 로고
    • Double blind, placebo controlled trial of the remission inducing and steroid sparing properties of an ICAM-1 antisense oligodeoxynucleotide, alicaforsen (ISIS 2302), in active steroid dependent Crohn's disease
    • Yacyshyn B.R., Chey W.Y., Goff J., Salzberg B., Baerg R., Buchman A.L., et al. Double blind, placebo controlled trial of the remission inducing and steroid sparing properties of an ICAM-1 antisense oligodeoxynucleotide, alicaforsen (ISIS 2302), in active steroid dependent Crohn's disease. Gut 51 (2002) 30-36
    • (2002) Gut , vol.51 , pp. 30-36
    • Yacyshyn, B.R.1    Chey, W.Y.2    Goff, J.3    Salzberg, B.4    Baerg, R.5    Buchman, A.L.6
  • 35
    • 33846804162 scopus 로고    scopus 로고
    • A randomized, double-masked, placebo-controlled study of alicaforsen, an antisense inhibitor of intercellular adhesion molecule 1, for the treatment of subjects with active Crohn's disease
    • Yacyshyn B., Chey W.Y., Wedel M.K., Yu R.Z., Paul D., Chuang E., et al. A randomized, double-masked, placebo-controlled study of alicaforsen, an antisense inhibitor of intercellular adhesion molecule 1, for the treatment of subjects with active Crohn's disease. Clin Gastroenterol Hepatol 5 (2007) 215-220
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 215-220
    • Yacyshyn, B.1    Chey, W.Y.2    Wedel, M.K.3    Yu, R.Z.4    Paul, D.5    Chuang, E.6
  • 36
    • 0035045185 scopus 로고    scopus 로고
    • Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease
    • Schreiber S., Nikolaus S., Malchow H., Kruis W., Lochs H., Raedler A., et al. Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease. Gastroenterology 120 (2001) 1339-1346
    • (2001) Gastroenterology , vol.120 , pp. 1339-1346
    • Schreiber, S.1    Nikolaus, S.2    Malchow, H.3    Kruis, W.4    Lochs, H.5    Raedler, A.6
  • 37
    • 7244252832 scopus 로고    scopus 로고
    • A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis
    • Van Deventer S.J., Tami J.A., and Wedel M.K. A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis. Gut 53 (2004) 1646-1651
    • (2004) Gut , vol.53 , pp. 1646-1651
    • Van Deventer, S.J.1    Tami, J.A.2    Wedel, M.K.3
  • 38
    • 33646271377 scopus 로고    scopus 로고
    • A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis
    • Van Deventer S.J., Wedel M.K., Baker B.F., Xia S., Chuang E., Miner P.B., et al. A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis. Aliment Pharmacol Ther 23 (2006) 1415-1425
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1415-1425
    • Van Deventer, S.J.1    Wedel, M.K.2    Baker, B.F.3    Xia, S.4    Chuang, E.5    Miner, P.B.6
  • 39
    • 33646232502 scopus 로고    scopus 로고
    • Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild to moderate left-sided ulcerative colitis: a randomized, double-blind, active-controlled trial
    • Miner P.B., Wedel M.K., Xia S., and Baker B.F. Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild to moderate left-sided ulcerative colitis: a randomized, double-blind, active-controlled trial. Aliment Pharmacol Ther 23 (2006) 1403-1413
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1403-1413
    • Miner, P.B.1    Wedel, M.K.2    Xia, S.3    Baker, B.F.4
  • 40
    • 0037285975 scopus 로고    scopus 로고
    • A pilot study on the use of the humanized anti-interleukin-2 receptor antibody daclizumab in active ulcerative colitis
    • Van Assche G., Dalle I., Noman M., Aerden I., Swijsen C., Asnong K., et al. A pilot study on the use of the humanized anti-interleukin-2 receptor antibody daclizumab in active ulcerative colitis. Am J Gastroenterol 98 (2003) 369-376
    • (2003) Am J Gastroenterol , vol.98 , pp. 369-376
    • Van Assche, G.1    Dalle, I.2    Noman, M.3    Aerden, I.4    Swijsen, C.5    Asnong, K.6
  • 41
    • 33750343050 scopus 로고    scopus 로고
    • Daclizumab, a humanised monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: a randomised, double blind, placebo controlled, dose ranging trial
    • Van Assche G., Sandborn W.J., Feagan B.G., Salzberg B.A., Silvers D., Monroe P.S., et al. Daclizumab, a humanised monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: a randomised, double blind, placebo controlled, dose ranging trial. Gut 55 (2006) 1568-1574
    • (2006) Gut , vol.55 , pp. 1568-1574
    • Van Assche, G.1    Sandborn, W.J.2    Feagan, B.G.3    Salzberg, B.A.4    Silvers, D.5    Monroe, P.S.6
  • 42
    • 10744232542 scopus 로고    scopus 로고
    • Basiliximab (anti-CD25) in combination with steroids may be an effective new treatment for steroid-resistant ulcerative colitis
    • Creed T.J., Norman M.R., Probert C.S., Harvey R.F., Shaw I.S., Smithson J., et al. Basiliximab (anti-CD25) in combination with steroids may be an effective new treatment for steroid-resistant ulcerative colitis. Aliment Pharmacol Ther 18 (2003) 65-75
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 65-75
    • Creed, T.J.1    Norman, M.R.2    Probert, C.S.3    Harvey, R.F.4    Shaw, I.S.5    Smithson, J.6
  • 43
    • 33646232018 scopus 로고    scopus 로고
    • Basiliximab for the treatment of steroid-resistant ulcerative colitis: further experience in moderate and severe disease
    • Creed T.J., Probert C.S., Norman M.N., Moorghen M., Shepherd N.A., Hearing S.D., et al. Basiliximab for the treatment of steroid-resistant ulcerative colitis: further experience in moderate and severe disease. Aliment Pharmacol Ther 23 (2006) 1435-1442
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1435-1442
    • Creed, T.J.1    Probert, C.S.2    Norman, M.N.3    Moorghen, M.4    Shepherd, N.A.5    Hearing, S.D.6
  • 45
    • 33746176176 scopus 로고    scopus 로고
    • Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease
    • Hommes D.W., Mikhajlova T.L., Stoinov S., Stimac D., Vucelic B., Lonovics J., et al. Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease. Gut 55 (2006) 1131-1137
    • (2006) Gut , vol.55 , pp. 1131-1137
    • Hommes, D.W.1    Mikhajlova, T.L.2    Stoinov, S.3    Stimac, D.4    Vucelic, B.5    Lonovics, J.6
  • 46
    • 33746132472 scopus 로고    scopus 로고
    • A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease
    • Reinisch W., Hommes D.W., Van Assche G., Colombel J.F., Gendre J.P., Oldenburg B., et al. A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease. Gut 55 (2006) 1138-1144
    • (2006) Gut , vol.55 , pp. 1138-1144
    • Reinisch, W.1    Hommes, D.W.2    Van Assche, G.3    Colombel, J.F.4    Gendre, J.P.5    Oldenburg, B.6
  • 47
    • 0034463305 scopus 로고    scopus 로고
    • Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group
    • Fedorak R.N., Gangl A., Elson C.O., Rutgeerts P., Schreiber S., Wild G., et al. Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group. Gastroenterology 119 (2000) 1473-1482
    • (2000) Gastroenterology , vol.119 , pp. 1473-1482
    • Fedorak, R.N.1    Gangl, A.2    Elson, C.O.3    Rutgeerts, P.4    Schreiber, S.5    Wild, G.6
  • 48
    • 0030835754 scopus 로고    scopus 로고
    • Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease. Crohn's Disease Study Group
    • Van Deventer S.J., Elson C.O., and Fedorak R.N. Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease. Crohn's Disease Study Group. Gastroenterology 113 (1997) 383-389
    • (1997) Gastroenterology , vol.113 , pp. 383-389
    • Van Deventer, S.J.1    Elson, C.O.2    Fedorak, R.N.3
  • 49
    • 0034464148 scopus 로고    scopus 로고
    • Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study Group
    • Schreiber S., Fedorak R.N., Nielsen O.H., Wild G., Williams C.N., Nikolaus S., et al. Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study Group. Gastroenterology 119 (2000) 1461-1472
    • (2000) Gastroenterology , vol.119 , pp. 1461-1472
    • Schreiber, S.1    Fedorak, R.N.2    Nielsen, O.H.3    Wild, G.4    Williams, C.N.5    Nikolaus, S.6
  • 50
    • 0034956334 scopus 로고    scopus 로고
    • Interleukin 10 (Tenovil) in the prevention of postoperative recurrence of Crohn's disease
    • Colombel J.F., Rutgeerts P., Malchow H., Jacyna M., Nielsen O.H., Rask-Madsen J., et al. Interleukin 10 (Tenovil) in the prevention of postoperative recurrence of Crohn's disease. Gut 49 (2001) 42-46
    • (2001) Gut , vol.49 , pp. 42-46
    • Colombel, J.F.1    Rutgeerts, P.2    Malchow, H.3    Jacyna, M.4    Nielsen, O.H.5    Rask-Madsen, J.6
  • 51
    • 11144358366 scopus 로고    scopus 로고
    • A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease
    • Ito H., Takazoe M., Fukuda Y., Hibi T., Kusugami K., Andoh A., et al. A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease. Gastroenterology 126 (2004) 989-996
    • (2004) Gastroenterology , vol.126 , pp. 989-996
    • Ito, H.1    Takazoe, M.2    Fukuda, Y.3    Hibi, T.4    Kusugami, K.5    Andoh, A.6
  • 52
    • 4344594765 scopus 로고    scopus 로고
    • A humanized anti-CD3 monoclonal antibody, visilizumab, for treatment of severe steroid-refractory ulcerative colitis: results of a phase I study
    • A7
    • Plevy S.E., Salzberg B.A., Regueiro M., Sandborn W., Hanauer S.B., Targan S.R., et al. A humanized anti-CD3 monoclonal antibody, visilizumab, for treatment of severe steroid-refractory ulcerative colitis: results of a phase I study. Gastroenterology 124, S1 (2003) A7
    • (2003) Gastroenterology , vol.124 S1
    • Plevy, S.E.1    Salzberg, B.A.2    Regueiro, M.3    Sandborn, W.4    Hanauer, S.B.5    Targan, S.R.6
  • 53
    • 29144506331 scopus 로고    scopus 로고
    • A phase I-II study: multiple dose levels of visilizumab are well tolerated and produce rapid and sustained improvement in ulcerative colitis patients refractory to treatment with IV steroids (IVSR-UC)
    • A-75
    • Targan S.R., Salzberg B.A., Mayer L., Hommes D., Hanauer S., Mahadevan U., et al. A phase I-II study: multiple dose levels of visilizumab are well tolerated and produce rapid and sustained improvement in ulcerative colitis patients refractory to treatment with IV steroids (IVSR-UC). Gastroenterology 128, S2 (2005) A-75
    • (2005) Gastroenterology , vol.128 S2
    • Targan, S.R.1    Salzberg, B.A.2    Mayer, L.3    Hommes, D.4    Hanauer, S.5    Mahadevan, U.6
  • 54
    • 24644495105 scopus 로고    scopus 로고
    • RDP58 is a novel and potentially effective oral therapy for ulcerative colitis
    • Travis S., Yap L.M., Hawkey C., Warren B., Lazarov M., Fong T., et al. RDP58 is a novel and potentially effective oral therapy for ulcerative colitis. Inflamm Bowel Dis 11 (2005) 713-719
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 713-719
    • Travis, S.1    Yap, L.M.2    Hawkey, C.3    Warren, B.4    Lazarov, M.5    Fong, T.6
  • 57
    • 1642575407 scopus 로고    scopus 로고
    • Crohn's-like ileo-colitis in patients affected by glycogen storage disease Ib: two years' follow-up of patients with a wide spectrum of gastrointestinal signs
    • Melis D., Parenti G., Della Casa R., Sibilio M., Berni Canani R., Terrin G., et al. Crohn's-like ileo-colitis in patients affected by glycogen storage disease Ib: two years' follow-up of patients with a wide spectrum of gastrointestinal signs. Acta Paediatr 92 (2003) 1415-1421
    • (2003) Acta Paediatr , vol.92 , pp. 1415-1421
    • Melis, D.1    Parenti, G.2    Della Casa, R.3    Sibilio, M.4    Berni Canani, R.5    Terrin, G.6
  • 58
    • 0031966917 scopus 로고    scopus 로고
    • Treatment of enteritis in chronic granulomatous disease with granulocyte colony stimulating factor
    • Myrup B., Valerius N.H., and Mortensen P.B. Treatment of enteritis in chronic granulomatous disease with granulocyte colony stimulating factor. Gut 42 (1998) 127-130
    • (1998) Gut , vol.42 , pp. 127-130
    • Myrup, B.1    Valerius, N.H.2    Mortensen, P.B.3
  • 59
    • 0026729095 scopus 로고
    • Brief report: treatment of chronic inflammatory bowel disease in glycogen storage disease type Ib with colony-stimulating factors
    • Roe T.F., Coates T.D., Thomas D.W., Miller J.H., and Gilsanz V. Brief report: treatment of chronic inflammatory bowel disease in glycogen storage disease type Ib with colony-stimulating factors. N Engl J Med 326 (1992) 1666-1669
    • (1992) N Engl J Med , vol.326 , pp. 1666-1669
    • Roe, T.F.1    Coates, T.D.2    Thomas, D.W.3    Miller, J.H.4    Gilsanz, V.5
  • 60
    • 18144432105 scopus 로고    scopus 로고
    • Use of GM-CSF in the treatment of colitis associated with chronic granulomatous disease
    • Wang J., Mayer L., and Cunningham-Rundles C. Use of GM-CSF in the treatment of colitis associated with chronic granulomatous disease. J Allergy Clin Immunol 115 (2005) 1092-1094
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 1092-1094
    • Wang, J.1    Mayer, L.2    Cunningham-Rundles, C.3
  • 61
    • 14644404938 scopus 로고    scopus 로고
    • An open-labelled study of granulocyte colony-stimulating factor in the treatment of active Crohn's disease
    • Korzenik J.R., and Dieckgraefe B.K. An open-labelled study of granulocyte colony-stimulating factor in the treatment of active Crohn's disease. Aliment Pharmacol Ther 21 (2005) 391-400
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 391-400
    • Korzenik, J.R.1    Dieckgraefe, B.K.2
  • 62
    • 0037048904 scopus 로고    scopus 로고
    • Treatment of active Crohn's disease with recombinant human granulocyte-macrophage colony-stimulating factor
    • Dieckgraefe B.K., and Korzenik J.R. Treatment of active Crohn's disease with recombinant human granulocyte-macrophage colony-stimulating factor. Lancet 360 (2002) 1478-1480
    • (2002) Lancet , vol.360 , pp. 1478-1480
    • Dieckgraefe, B.K.1    Korzenik, J.R.2
  • 65
    • 15744405106 scopus 로고    scopus 로고
    • Autologous hematopoietic stem cell transplantation in patients with refractory Crohn's disease
    • Oyama Y., Craig R.M., Traynor A.E., Quigley K., Statkute L., Halverson A., et al. Autologous hematopoietic stem cell transplantation in patients with refractory Crohn's disease. Gastroenterology 128 (2005) 552-563
    • (2005) Gastroenterology , vol.128 , pp. 552-563
    • Oyama, Y.1    Craig, R.M.2    Traynor, A.E.3    Quigley, K.4    Statkute, L.5    Halverson, A.6
  • 66
    • 0037372443 scopus 로고    scopus 로고
    • High-dose immune suppression and autologous hematopoietic stem cell transplantation in refractory Crohn disease
    • Burt R.K., Traynor A., Oyama Y., and Craig R. High-dose immune suppression and autologous hematopoietic stem cell transplantation in refractory Crohn disease. Blood 101 (2003) 2064-2066
    • (2003) Blood , vol.101 , pp. 2064-2066
    • Burt, R.K.1    Traynor, A.2    Oyama, Y.3    Craig, R.4
  • 68
    • 0038095378 scopus 로고    scopus 로고
    • Multicenter randomized controlled trial for the treatment of ulcerative colitis with a leukocytapheresis column
    • Sawada K., Muto T., Shimoyama T., Satomi M., Sawada T., Nagawa H., et al. Multicenter randomized controlled trial for the treatment of ulcerative colitis with a leukocytapheresis column. Curr Pharm Des 9 (2003) 307-321
    • (2003) Curr Pharm Des , vol.9 , pp. 307-321
    • Sawada, K.1    Muto, T.2    Shimoyama, T.3    Satomi, M.4    Sawada, T.5    Nagawa, H.6
  • 69
    • 21344464465 scopus 로고    scopus 로고
    • Leukocytapheresis in ulcerative colitis: results of a multicenter double-blind prospective case-control study with sham apheresis as placebo treatment
    • Sawada K., Kusugami K., Suzuki Y., Bamba T., Munakata A., Hibi T., et al. Leukocytapheresis in ulcerative colitis: results of a multicenter double-blind prospective case-control study with sham apheresis as placebo treatment. Am J Gastroenterol 100 (2005) 1362-1369
    • (2005) Am J Gastroenterol , vol.100 , pp. 1362-1369
    • Sawada, K.1    Kusugami, K.2    Suzuki, Y.3    Bamba, T.4    Munakata, A.5    Hibi, T.6
  • 70
    • 4444274915 scopus 로고    scopus 로고
    • Adsorptive granulocyte and monocyte apheresis versus prednisolone in patients with corticosteroid-dependent moderately severe ulcerative colitis
    • Hanai H., Watanabe F., Yamada M., Sato Y., Takeuchi K., Iida T., et al. Adsorptive granulocyte and monocyte apheresis versus prednisolone in patients with corticosteroid-dependent moderately severe ulcerative colitis. Digestion 70 (2004) 36-44
    • (2004) Digestion , vol.70 , pp. 36-44
    • Hanai, H.1    Watanabe, F.2    Yamada, M.3    Sato, Y.4    Takeuchi, K.5    Iida, T.6
  • 71
    • 0027979011 scopus 로고
    • Treatment of Crohn's disease by lymphocyte apheresis: a randomized controlled trial. Groupe d'Etudes Therapeutiques des Affections Inflammatoires Digestives
    • Lerebours E., Bussel A., Modigliani R., Bastit D., Florent C., Rabian C., et al. Treatment of Crohn's disease by lymphocyte apheresis: a randomized controlled trial. Groupe d'Etudes Therapeutiques des Affections Inflammatoires Digestives. Gastroenterology 107 (1994) 357-361
    • (1994) Gastroenterology , vol.107 , pp. 357-361
    • Lerebours, E.1    Bussel, A.2    Modigliani, R.3    Bastit, D.4    Florent, C.5    Rabian, C.6
  • 72
    • 33749013296 scopus 로고    scopus 로고
    • Helminths and mucosal immune modulation
    • Weinstock J.V. Helminths and mucosal immune modulation. Ann N Y Acad Sci 1072 (2006) 356-364
    • (2006) Ann N Y Acad Sci , vol.1072 , pp. 356-364
    • Weinstock, J.V.1
  • 73
    • 0141459691 scopus 로고    scopus 로고
    • Trichuris suis seems to be safe and possibly effective in the treatment of inflammatory bowel disease
    • Summers R.W., Elliott D.E., Qadir K., Urban J.F., Thompson R., Weinstock J.V., et al. Trichuris suis seems to be safe and possibly effective in the treatment of inflammatory bowel disease. Am J Gastroenterol 98 (2003) 2034-2041
    • (2003) Am J Gastroenterol , vol.98 , pp. 2034-2041
    • Summers, R.W.1    Elliott, D.E.2    Qadir, K.3    Urban, J.F.4    Thompson, R.5    Weinstock, J.V.6
  • 75
  • 76
    • 2442453484 scopus 로고    scopus 로고
    • Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics
    • Sartor R.B. Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics. Gastroenterology 126 (2004) 1620-1633
    • (2004) Gastroenterology , vol.126 , pp. 1620-1633
    • Sartor, R.B.1
  • 77
    • 0038185270 scopus 로고    scopus 로고
    • Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial
    • Gionchetti P., Rizzello F., Helwig U., Venturi A., Lammers K.M., Brigidi P., et al. Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. Gastroenterology 124 (2003) 1202-1209
    • (2003) Gastroenterology , vol.124 , pp. 1202-1209
    • Gionchetti, P.1    Rizzello, F.2    Helwig, U.3    Venturi, A.4    Lammers, K.M.5    Brigidi, P.6
  • 78
    • 9144254035 scopus 로고    scopus 로고
    • Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis
    • Mimura T., Rizzello F., Helwig U., Poggioli G., Schreiber S., Talbot I.C., et al. Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis. Gut 53 (2004) 108-114
    • (2004) Gut , vol.53 , pp. 108-114
    • Mimura, T.1    Rizzello, F.2    Helwig, U.3    Poggioli, G.4    Schreiber, S.5    Talbot, I.C.6
  • 79
    • 4644239296 scopus 로고    scopus 로고
    • Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine
    • Kruis W., Fric P., Pokrotnieks J., Lukás M., Fixa B., Kascák M., et al. Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine. Gut 53 (2004) 1617-1623
    • (2004) Gut , vol.53 , pp. 1617-1623
    • Kruis, W.1    Fric, P.2    Pokrotnieks, J.3    Lukás, M.4    Fixa, B.5    Kascák, M.6
  • 80
    • 25444512029 scopus 로고    scopus 로고
    • A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease
    • Bousvaros A., Guandalini S., Baldassano R.N., Botelho C., Evans J., Ferry G.D., et al. A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease. Inflamm Bowel Dis 11 (2005) 833-839
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 833-839
    • Bousvaros, A.1    Guandalini, S.2    Baldassano, R.N.3    Botelho, C.4    Evans, J.5    Ferry, G.D.6
  • 81
    • 33646756180 scopus 로고    scopus 로고
    • Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn's disease: a randomised, double blind, placebo controlled GETAID trial
    • Marteau P., Lemann M., Seksik P., Laharie D., Colombel J.F., Bouhnik Y., et al. Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn's disease: a randomised, double blind, placebo controlled GETAID trial. Gut 55 (2006) 842-847
    • (2006) Gut , vol.55 , pp. 842-847
    • Marteau, P.1    Lemann, M.2    Seksik, P.3    Laharie, D.4    Colombel, J.F.5    Bouhnik, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.