Bioproduction of diosgenin in callus cultures of Balanites aegyptiaca: Effect of growth regulators, explants and somatic embryogenesis

Natural Product Communications

Volumn 1, Issue 3, 2006, Pages 215-221

  Chapagain, Bishnu P ^a   Saharan, Vinod ^a,b   Pelah, Dan ^a   Yadav, Ram C ^b   Wiesman, Zeev ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b CCS HARYANA AGRICULTURAL UNIVERSITY   (India)

Author keywords

Balanites aegyptiaca; Bioproduction; Callus; Diosgenin; Embryoenesis; Explants; PGR

Indexed keywords

EID: 37049008374     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x0600100308     Document Type: Article

References (27)

1. Liu MJ, Wang Z, Ju Y, Wong RN, Wu QY. (2005) Diosgenin induces cell cycle arrest and apoptosis in human leukemia K562 cells with the disruption of Ca2+ homeostasis. Cancer Chemotherapy and Pharmacology, 55, 79-90.
2. Roman ID, Thewles A, Coleman R. (1995) Fractionation of livers following diosgenin treatment to elevate binary cholesterol. Biochimica et Biophysica Acta, 1255, 77-81.
3. Aradhana AR, Kale RK. (1992) Diosgenin-A growth stimulator of mammary gland of ovariectomized mouse. Indian Journal of Experimental Biology, 30, 367-370.
4. Moalic S, Liagre B, Corbiere C, Bianchi A, Danca M, Bordji K, Beneytout JL. (2001) A plant steroid diosgenin, induces apoptosis, cell cycle arrest and cox activity in osteosarcoms cells. FEBS Letters, 506, 205-230.
5. Corbiere C, Liagre B, Bianchi A, Bordji K, Dauca M, Netter P, Beneytout JL. (2003) Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells. International Journal of Oncology, 22, 899-905.
6. Beneytout JL, Nappez C, Leboutet MJ, Malivvand G. (1995) A plant steroid, diosgenin a new megakaryocytic differentiation induce of HEL cell. Biochemical and Biophysical Research Communications, 207, 398-404.
7. Nappez C, Liagre B, Beneytout JL. (1995) Changes in lipoxygenase activities in human erythroleukemia (HEL) cells during diosgenin-induced differentiation. Cancer Letters, 96, 133-140.
8. Zenk MH. (1978) The impact of plant cell cultures on industry. In Thorpe TA (ed) Frontiers of Plant Tissue Culture, University of Calgary Press, Alberta, pp. 1-13.
9. Hall JB, Walker DH. (1991) Balanites aegyptiaca Del: A Monograph. Bangor: School of Agricultural and Forestry Sciences Publication, University of Wales, Banger.
10. Savikin-Fodulovic K, Grubisic D, Culafic L, Menkovic N, Ristic M. (1998) Diosgenin and phytosterols content in five callus lines of Dioscorea balcanica. Plant Science, 135, 63-67.
11. Kamel MS, Koskinen A. (1995) Pregnane glycosides from fruits of Balanites aegyptiaca. Phytochemistry, 40, 1773-1775.
12. Neuwinger HD (1996) African Ethnobotany: Poisons and Drug: Chemistry, Pharmacology and Toxicology. Weinheim: Chapman and Hall GmbH.
13. Chapagain B. Wiesman Z. (2005) Larivicidal activity of the fruit mesocarp extract of Balanites aegyptiaca and its saponin fractions against dengue vector. Dengue Bulletin, 30, (In press).
14. Chapagain B, Wiesman Z. (2005) Variation in diosgenin level in seed kernels among different provenances of Balanites aegyptiaca Del. (Zygophyllaceae) and its correlation with oil content. African Journal of Biotechnology, 4, 1209-1213.
15. Ndoye M, Diallo I, Gassama-Dia, YK. (2003) In vitro multiplication of the semi arid forest tree, Balanites aegyptiaca (L.) Del. African Journal of Biotechnology, 2, 421-423.
16. Nour M, El Khalifa, Massimo K, El Hassen B. (1991) Preliminary study on seed pregermination treatment and vegetative propagation of Balanites aegyptiaca (L.) Del. In : Physiologie des Arbres et Arbustes en zone arides et semi-Arides.-Paris, France: Groupe d'Etude de l'arbre, pp 413-415.
17. Mulabagal V, Tsay HS. (2004) Plant Cell Cultures-An Alternative and Efficient Source for the Production of Biologically Important Secondary Metabolites. International Journal of Applied Science and Engineering, 2, 29-48.
18. Ikenaga T, Handayani R, Oyama T. (2000) Steroidal saponin production in callus cultures of Solanum aculeatissimum Jacq. Plant Cell Reports, 19, 1240-1244.
19. Oncina R, Botia JM, Del Rio JA, Ortuño A. (2000) Bioproduction of diosgenin in callus culture of Trigonella foenum-graecum L. Food Chemistry, 70, 489-492.
20. Suthar KC, Ramawat KG, Arya HC. (1980) Effect of growth regulators on diosgenin production in Balanites aegyptiaca (L.) Dellile. Indian Journal of Experimental Biology, 18, 1207-1211.
21. Merkli A, Christen P, Kapetanidis I. (1997) Production of diosgenin by hairy root cultures of Trigonella foenum-graecum L. Plant Cell Reports, 16, 632-636.
22. Murashige T, Skoog F. (1962) A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiologia Plantarum, 15, 473-497.
23. Baccou JC, Lamber F, SauvaireY. (1977) Spectrophotometric methods for the determination of total steroidal sapogenin. Analyst, 102, 458-465.
24. Uematsu Y, Hirata K, Saito K. (2000) Spectrophotometric Determination of Saponin in Yucca Extract Used as Food Additive. Journal of AOAC International, 83, 1451-1454.
25. SAS (2000) JMP: User's Guide, Version 4. Cary, NC: SAS Institute Inc.
26. Asaka I, Hirotani M, Asada Y, Furuya T. (1993) Production of ginsenoside saponins by culturing ginseng (Panax ginseng) embryogenetic tissues in bioreactors. Biotechnology Letters, 15, 1259-1264.
27. Wu J, Lin L. (2002) Elicitor-like effects of low-energy ultrasound on plant (Panax ginseng) cells: induction of plant defense responses and secondary metabolite production. Applied Microbiology and Biotechnology, 59, 51-57.