Ginkgolide C inhibits platelet aggregation in cAMP- and cGMP-dependent manner by activating MMP-9

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 12, 2007, Pages 2340-2344

  Cho, Hyun Jeong ^a   Shon, Yun Hee ^b   Nam, Kyung Soo ^c  

^a Dongguk University   (South Korea)

^b Intractable Disease Research Center   (South Korea)

^c Dongguk University College of Medicine   (South Korea)

Author keywords

Cyclic nucleotide; Ginkgolide C; Intracellular Ca2+; Matrix metalloproteinase 9; Platelet aggregation

Indexed keywords

COLLAGEN; CYCLIC AMP; CYCLIC GMP; GELATINASE B; GINKGOLIDE C; THROMBOXANE A2;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL SECRETION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; ENZYME RELEASE; GINKGO BILOBA; NONHUMAN; PHARMACODYNAMICS; PLANT LEAF; PROTEIN SYNTHESIS; RAT; THROMBOCYTE; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; ZYMOGRAPHY;

ANIMALS; CALCIUM; COLLAGEN; CYCLIC AMP; CYCLIC GMP; GINKGOLIDES; LACTONES; MALE; MATRIX METALLOPROTEINASE 9; PLANT EXTRACTS; PLATELET AGGREGATION; RATS; RATS, SPRAGUE-DAWLEY; THROMBOXANE A2;

EID: 36849090563     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.2340     Document Type: Article

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