Inhibitory effect of GBH on platelet aggregation through inhibition of intracellular Ca 2+ mobilization in activated human platelets

Life Sciences

Volumn 75, Issue 25, 2004, Pages 3063-3076

  Park, Won Hwan ^a   Kim, Han Kyu ^a   Nam, Kyung Soo ^b   Shon, Yun Hee ^b   Jeon, Byung Hun ^c   Moon, Sung Kwon ^d   Kim, Min Gon ^e   Kim, Cheorl Ho ^a  

^a Department of Biochemistry   (South Korea)

^b Dongguk University   (South Korea)

^c Wonkwang University   (South Korea)

^d Chungju National University   (South Korea)

^e Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Arachidonic acid; Geiji Bokryung Hwan (GBH); Korean herbal medicine; Phosphoinositide; Platelet aggregation; Thromboxane A 2, Ca 2+ I; Thromboxane synthetase

Indexed keywords

ANTITHROMBOCYTIC AGENT; CINNAMOMI RAMULUS EXTRACT; COLLAGEN RELATED PEPTIDE; CYCLIC AMP; CYCLIC GMP; GEIJI BOKRYUNG HWAN; INOSITOL 1,4,5 TRISPHOSPHATE; MOUNTAN CORTEX RADICIS EXTRACT; PAEONIA RADIX; PEPTIDE; PERSICAE SEMEN EXTRACT; PHOSPHOLIPASE; PLANT EXTRACT; PORIA COCOS EXTRACT; THROMBOXANE B2; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM MOBILIZATION; CINNAMOMI RAMULUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; MEDICINAL PLANT; MOUNTAN CORTEX RADICIS; PERSICAE SEMEN; PORIA COCOS; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

BLOOD PLATELETS; CALCIUM; CARRIER PROTEINS; CYCLIC AMP; CYCLIC GMP; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; KOREA; MEDICINE, HERBAL; PEPTIDES; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; THROMBIN; THROMBOXANE B2;

COCOS; PORIA COCOS;

EID: 4944252389     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.07.010     Document Type: Article

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