Serum interleukin-13 levels are increased in patients with Stevens-Johnson syndrome/toxic epidermal necrolysis but not in those with erythema multiforme [9]

British Journal of Dermatology

Volumn 158, Issue 1, 2008, Pages 184-186

  Quaglino, P ^a   Caproni, M ^b   Osella Abate, S ^a   Torchia, D ^b   Comessatti, A ^a   Del Bianco, E ^b   Antiga, E ^b   Frezzolini, A ^c   Schena, D ^d   Marzano, A ^e   De Simone, C ^f   Parodi, A ^g   Fabbri, P ^b   Bernengo, M G ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^d UNIVERSITY OF VERONA   (Italy)

^e UNIVERSITY OF MILAN   (Italy)

^f SAN CAMILLO FORLANINI HOSPITAL   (Italy)

^g UNIVERSITY OF GENOA   (Italy)

Author keywords

Enzyme linked immunosorbent assay; Erythema multiforme; Fas; Interleukin 13; Stevens Johnson syndrome; Toxic epidermal necrolysis

Indexed keywords

INTERLEUKIN 13;

ERYTHEMA MULTIFORME; HUMAN; INFLAMMATION; LETTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL ANALYSIS; STEVENS JOHNSON SYNDROME; TOXIC EPIDERMAL NECROLYSIS;

EPIDERMAL NECROLYSIS, TOXIC; ERYTHEMA MULTIFORME; HUMANS; INTERLEUKIN-13; STEVENS-JOHNSON SYNDROME;

EID: 36849086852     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2007.08259.x     Document Type: Letter

References (10)

1. Izuhara K, Arima K. Signal transduction of IL-13 and its role in the pathogenesis of bronchial asthma. Drug News Perspect 2004 17 : 91 8.
2. Wynn TA. IL-13 effector functions. Annu Rev Immunol 2003 21 : 425 56.
3. Bastuji-Garin S, Rzany B, Stern RS et al. Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme. Arch Dermatol 1993 129 : 92 6.
4. Posadas SJ, Torres MJ, Mayorga C et al. Gene expression levels of cytokine profile and cytotoxic markers in non-immediate reactions to drugs. Blood Cells Mol Dis 2002 29 : 179 89.
5. Aurelian L, Ono F, Burnett J. Herpes simplex virus (HSV)-associated erythema multiforme (HAEM): a viral disease with an autoimmune component. Dermatol Online J 2003 9 : 1.
6. Correia O, Delgado L, Barbosa IL et al. Increased interleukin 10, tumor necrosis factor alpha, and interleukin 6 levels in blister fluid of toxic epidermal necrolysis. J Am Acad Dermatol 2002 47 : 58 62.
7. Nassif A, Moslehi H, Le Gouvello S et al. Evaluation of the potential role of cytokines in toxic epidermal necrolysis. J Invest Dermatol 2004 123 : 850 5.
8. Caproni M, Torchia D, Schincaglia E et al. Expression of cytokines and chemokine receptors in the cutaneous lesions of erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis. Br J Dermatol 2006 155 : 722 8.
9. Quaglino P, Caproni M, Antiga E et al. Serum levels of the Th1 promoter IL-12 and the Th2 chemokine TARC are elevated in erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis and correlate with soluble Fas ligand expression. An immunoenzymatic study from the Italian Group of Immunopathology. Dermatology 2007 214 : 296 304.
10. Nishio D, Izu K, Kabashima K, Tokura Y. T cell populations propagating in the peripheral blood of patients with drug eruptions. J Dermatol Sci 2007 48 : 25 33.