Association of TNF- α -308 G/A and IL-4 -589 C/T gene promoter polymorphisms with asthma susceptibility in the South of Iran

Journal of Investigational Allergology and Clinical Immunology

Volumn 17, Issue 6, 2007, Pages 361-366

  Kamali Sarvestani, Eskandar ^a,b   Ghayomi, M A ^a   Nekoee, A ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Asthma; Interleukin 4; Polymorphism; Tumor necrosis factor

Indexed keywords

ALANINE; CYTOSINE; GUANINE; INTERLEUKIN 4; THREONINE; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; ASTHMA; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DISEASE SEVERITY; DNA POLYMORPHISM; FEMALE; FORCED EXPIRATORY VOLUME; GENE FREQUENCY; GENOTYPE; HUMAN; IRAN; MAJOR CLINICAL STUDY; MALE; PROMOTER REGION;

ADOLESCENT; ADULT; AGED; ASTHMA; FEMALE; FORCED EXPIRATORY VOLUME; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERLEUKIN-4; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); TUMOR NECROSIS FACTOR-ALPHA; VITAL CAPACITY;

EID: 36849085805     PISSN: 10189068     EISSN: 16980808     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Sandford A, Weir T, Pare P. The genetics of asthma. Am J Respire Crit Care Med. 1996;153:1749-65.
2. Bjorksten B. The environmental influence on childhood asthma. Allergy. 1999;54 Suppl 49:17-23.
3. Halasz A, Cserhati E, Magyar P, Kovacs M, Cseh K. Role of TNF-α and its 55 and 75 KDa receptors in bronchial hyperreactivity. Respir Med. 2002;96:262-7.
4. Thomas PS. Tumour necrosis factor-alpha: the role of this multifunctional cytokine in asthma. Immunol Cell Biol. 2001;79:132-40.
5. Bradding P, Roberts JA, Britten KM, Montefort S. Interleukin-4, 5, 6 and tumor necrosis factor-α in normal and asthmatic airways: evidence for the human mast cells as a source of these cytokine. Am J Respir Cell Mol Biol. 1994;10:471-80.
6. Taki F, Torii K, Ikuta N. Increased level of TNF concentration in sputa of patients with bronchial asthma. Am Rev Respir Dis. 1991;143:A13.
7. Broide DH, Lotz M, Cuomo AJ. Cytokines in symptomatic asthma airways. J Allergy Clin Immunol. 1992;89:958-67.
8. Wilson A G, di Giovine FS, Blakemore AlF, Duff GW. Single Base polymorphisms in the human tumor necrosis factor alpha (TNF-α) gene detected by NcoI restriction of PCR product. Hum Mol Genet. 1992;1:353.
9. Moffat MF, James A, Ryan G, Musk AW, Cookson WOCM. Extended tumor necrosis factor/HLA-Dr haplotypes and asthma in Australian population sample. Thorax. 1999;54:757-61.
10. Chagani T, Pare PD, Shoukang Z, Weir TD, Bai TR, Behbehani NA, Fitzgerald M, Sandford AJ. Prevalence of tumor necrosis factor alpha and angiotensin converting enzyme polymorphisms in mild/moderate and fatal/near fatal asthma. Am J Respir Crit Care Med. 1999;160:278-82.
11. Albuquerque RV, Hayden CM, Palmer LJ, Laing IA, Rye PJ, Gibason NA, Burton PR, Goldblatt J, Lesouef PN. Association of polymorphisms within the TNF genes and childhood asthma. Clin Exp Allergy. 1998;28:578-84.
12. Gupta V, Sarin BC, Changotra H, Sehaipal PK. Association of G-308A TNF-alpha polymorphism with bronchial asthma in North Indian population. J Asthma. 2005;42:839-41.
13. Tan EC, Lee BW, Tay AWN, Chew FT, Tay AHN. Asthma and TNF variants in Chinese and Malays. Allergy. 1999;54:402-3.
14. Louis R, Leyder E, Malaise M, Bartsch P, Louis E. Lack of association between adult asthma and the tumour necrosis factor alpha-308 polymorphism gene. Eur Respir J. 2000;16:604-8
15. Paul W. Interleukin-4: a prototypic immunoregulatory lymphokine. Blood. 1999;77:1859-70.
16. Schleimer RP, Strebinsky SA, Kaiser J, Bichel CA, Klunk DA, Tomioka K, Newman W, Luscinskas FW, Jr Gimbrone MA, McIntyre BW. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1. J Immunol. 1992;148:1086-92.
17. Gelder CM, Thomas PS, Yates DH, Adcoch IM, Morrison JF, Barnes PJ. Cytokine expression in normal, atopic, and asthmatic subjects using the combination of sputum induction and the polymerase chain reaction. Thorax. 1995;50:1033-7.
18. Walker C, Bode E, Boer L, Hansel TT, Blaser K, Virchow JC jr. Allergic and non allergic asthmatics have distinct patterns of T-cell activation and cytokine production peripheral blood and bronchoalveolar lavage. Am Rev Respir Dis. 1992;146:109-15.
19. Rosenwasser LJ, Klemm DJ, Dresback JK. Promoter Polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exp Allergy. 1995;2 Suppl 2: S74-8; discussion 95-6.
20. Beghe B, Barton S, Rorke S, Peng Q, Sayers I, Gaunt T, Keiths TP, Clough JB, Holgate ST, Holloway JW. Polymorphisms in the interleukin-4 and interleukin-4 receptor α chain genes confer susceptibility to asthma and atopy in a Caucasian population. Clin Exp Allergy. 2003;33:1111-7.
21. Noguchi EM, Shibasaki T, Arinami K, Takeda Y, Yokouchi T, Kawashima H, Yanagi A, Matsui, Hamaguchi H. Association of asthma and the interleukin-4 promoter gene in Japanese. Clin Exp Allergy. 1998;28:449-53.
22. Walley AJ, Cookson WOCM. Investigation of an interleukin-4 promoter polymorphism for association with asthma and atopy. J Med Genet. 1996;33:689-692.
23. National Institutes of Health. Global initiative for asthma. Natl Heart Lung Blood Inst Publ. No. 95-3659. Bethesda, MD: NHLBI 1995;6,.
24. American Thoracic Society. Standardization of spirometry: 1987 update. Am Rev Respir Dis. 1987;136:1285-98.
25. Drazen J, Weinberger SE. Approach to the patient with disease of the respiratory system. In: Braunwald E, Kasper DL, Hauser SL, Fauci A, Longo DL, Jameson JL, editors. Harrison's principles of internal medicine. New York: McGraw-Hill; 2001. p.1443-1453.
26. Olerup O, Zetterquist H. HLA-DR typing by PCR amplification with sequence specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens. 1992;39:225-35.
27. Verjans GM, Brinkman BM, Van Doornik CE, Kijlstra, A, Verweij CL. Polymorphism of tumour necrosis factor-alpha (TNF-alpha) at position -308 in relation to ankylosing spondylitis. Clin Exp Immunol. 1994;97:45-7.
28. Kawashima T, Noguchi E, Arinami T, Yamakawa-Kobayashi K, Nakagawa H, Otsuka F, Hamaguchi H. Linkage and association of an interleukin 4 gene Polymorphism with atopic dermatitis in Japanese families. J Med Genet. 1998;35:502-4.
29. Jacob CO, Fronek Z, Levis GD, Koo M, Hansen JA, McDevit HO. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci USA. 1990;87:1233-7.
30. Skoog T, Van't Hooft FM, kallim B, Jovinge S, Boquist S, Nillson J, Eriksson P, Hamsten A. A common functional polymorphism (C→A substitution position -863) in the promoter region of the tumor necrosis factor-α (TNF-α) gene associated with reduced circulating levels of TNF-α. Hum Mol Genet. 1999;8:1443-9.
31. Esteban G, Burchard EG, Silverman EK, Rosenwasser LJ. Association between a sequence variant in the IL-4 gene promoter and FEV1 in asthma. Am J Respir Crit Care Med. 1999;160:919-22.
32. Shome GP, Stames JD, Shearer M, Kennedy R, Way A, Arif A, Prabhakar S. Exhaled nitric oxide in asthma: variability, relation to asthma severity, and peripheral blood lymphocyte cytokine expression. J Asthma. 2006;43:95-9.
33. Borger P, Ten Hacken NH, Vellenga E, Kauffman HF, Postma DS. Peripheral blood T lymphocytes from asthmatic patients are primed for enhanced expression of interleukin (IL)-4 and IL-5 mRNA: associations with lung function and serum IgE. Clin Exp Allergy. 1999;29:772-9.